Results 11 to 20 of about 76,131 (358)
BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation [PDF]
Nucleic Acids Research, 2017 Mutations in SOX10 cause neurocristopathies which display varying degrees of hypopigmentation. Using a sensitized mutagenesis screen, we identified Smarca4 as a modifier gene that exacerbates the phenotypic severity of Sox10 haplo-insufficient mice ...
Dawn E Watkins-Chow +2 more
exaly +2 more sources
Vitiligo and the melanocyte reservoir
Indian Journal of Dermatology, 2009 Repigmentation of vitiligo depends on available melanocytes from three possible sources: from the hair follicle unit which is the main provider of pigment cells, from the border of vitiligo lesions, and from unaffected melanocytes within depigmented ...
Falabella Rafael
doaj +4 more sources
eLife, 2023 Tissue-resident stem and progenitor cells are present in many adult organs, where they are important for organ homeostasis and repair in response to injury. However, the signals that activate these cells and the mechanisms governing how these cells renew
William Tyler Frantz +5 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2023 Melanoma is the deadliest form of skin cancer and develops from the melanocytes that are responsible for the pigmentation of the skin. The skin is also a highly regenerative organ, harboring a pool of undifferentiated melanocyte stem cells that ...
Esra Katkat +10 more
doaj +1 more source
The First Live-Cell Based Product in The Iranian Drug List; ReColorCell® [PDF]
Cell Journal, 2023 Vitiligo is an autoimmune skin disorder that can significantly affect the quality of life in patients. However, currenttreatment strategies such as phototherapy, topical glucocorticosteroids, or systemic immunosuppressants canbe helpful in vitiligo ...
Mohammad Amin Shahrbaf +2 more
doaj +1 more source
The neuropeptide alpha-melanocyte-stimulating hormone is critically involved in the development of cytotoxic CD8+ T cells in mice and humans. [PDF]
PLoS ONE, 2010 BACKGROUND: The neuropeptide alpha-melanocyte-stimulating hormone is well known as a mediator of skin pigmentation. More recently, it has been shown that alpha-melanocyte-stimulating hormone also plays pivotal roles in energy homeostasis, sexual function,
Karin Loser +10 more
doaj +1 more source
A Study of Normal Epidermal Melanocyte Distribution
International Journal of Dermatology and Venerology, 2021 . Objective:. To elucidate the epidermal melanocyte distribution according to sex, age, and body part with the goal of providing benchmark data for the diagnosis and therapeutic effect evaluation of pigmentary skin diseases. Methods:.
Kai-Lv Sun +4 more
doaj +1 more source
Melanogenesis and hypopigmentation: The case of vitiligo
Indian Journal of Dermatology, 2022 Melanocytes are highly specialized dendritic cells that synthesize and store melanin in subcellular organelles called melanosomes, before transfer to keratinocytes.
M Pilar Vinardell +2 more
doaj +1 more source
Coordinated regulation of chromatophore differentiation and melanogenesis during the ontogeny of skin pigmentation of Solea senegalensis (Kaup, 1858) [PDF]
, 2013 Abnormal pigmentation of Senegalese sole has been described as one problem facing the full exploitation of its commercial production. To improve our understanding of flatfish pigmentation of this commercially important species we have evaluated eleven ...
Alicia Estévez +6 more
core +10 more sources
Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish. [PDF]
PLoS Genetics, 2007 The establishment of a single cell type regeneration paradigm in the zebrafish provides an opportunity to investigate the genetic mechanisms specific to regeneration processes.
Chao-Tsung Yang +3 more
doaj +1 more source