Results 11 to 20 of about 62,888 (340)

Vitiligo and the melanocyte reservoir

open access: yesIndian Journal of Dermatology, 2009
Repigmentation of vitiligo depends on available melanocytes from three possible sources: from the hair follicle unit which is the main provider of pigment cells, from the border of vitiligo lesions, and from unaffected melanocytes within depigmented ...
Falabella Rafael
doaj   +4 more sources

Melanocytes and Their Diseases [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2014
Human melanocytes are distributed not only in the epidermis and in hair follicles but also in mucosa, cochlea (ear), iris (eye), and mesencephalon (brain) among other tissues. Melanocytes, which are derived from the neural crest, are unique in that they produce eu-/pheo-melanin pigments in unique membrane-bound organelles termed melanosomes, which can ...
Vincent J. Hearing, Yuji Yamaguchi
openaire   +3 more sources

Melanocytic schwannoma [PDF]

open access: yesCancer, 1988
The clinical, histopathologic, immunohistochemical, and electron microscopic findings of two cases of melanocytic schwannoma are reported. One case, which occurred in the parotid gland, is believed to be the first reported in this location. The other case was located in the sacral spinal region.
Roberta M. Killeen   +2 more
openaire   +3 more sources

Super-High Magnification Dermoscopy in 190 Clinically Atypical Pigmented Lesions

open access: yesDiagnostics, 2023
Super-high (×400) magnification dermoscopy (D400) is a new non-invasive imaging technique that has been shown to add information for the differential diagnosis of melanocytic lesions in a pilot study.
Elisa Cinotti   +8 more
doaj   +1 more source

Melanocyte Function and Count of Leukotrichia in Vitiligo Using S100 Immunohistochemistry and Microphtalmia Associated Transcription Factor (MITF)

open access: yesBerkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2017
Background: Melanocyte of the hair follicle is one of the major sources of repigmentation in vitiligo. Leukotrichia is complete depigmentation with significant bleaching hair.
M. Yulianto Listiawan   +2 more
doaj   +1 more source

A Comparison Between Phorbol 12 Myristate 13 Acetate and Phorbol 12, 13 Dibutyrate in Human Melanocyte Culture [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: Melanocyte culture is an integral part of the studies of skin biology and cosmetic applications. After the introduction of selective medium for the culture of human melanocyte using Phorbol 12-myristate13-acetate (PMA) in 1982, a lot of ...
Divya Padma, Kumar M.R. Bhat
doaj   +1 more source

Detection of Cellular Senescence in Human Primary Melanocytes and Malignant Melanoma Cells In Vitro

open access: yesCells, 2022
Detection and quantification of senescent cells remain difficult due to variable phenotypes and the absence of highly specific and reliable biomarkers. It is therefore widely accepted to use a combination of multiple markers and cellular characteristics ...
Tom Zimmermann   +5 more
doaj   +1 more source

Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway [PDF]

open access: yes, 2009
Melanocortin-1 receptor (MC1R) and its ligands, a-melanocyte stimulating hormone (aMSH) and agouti signaling protein (ASIP), regulate switching between eumelanin and pheomelanin synthesis in melanocytes.
Abdel-Malek   +45 more
core   +2 more sources

An iterative genetic and dynamical modelling approach identifies novel features of the gene regulatory network underlying melanocyte development.

open access: yesPLoS Genetics, 2011
The mechanisms generating stably differentiated cell-types from multipotent precursors are key to understanding normal development and have implications for treatment of cancer and the therapeutic use of stem cells.
Emma R Greenhill   +4 more
doaj   +1 more source

The First Live-Cell Based Product in The Iranian Drug List; ReColorCell® [PDF]

open access: yesCell Journal, 2023
Vitiligo is an autoimmune skin disorder that can significantly affect the quality of life in patients. However, currenttreatment strategies such as phototherapy, topical glucocorticosteroids, or systemic immunosuppressants canbe helpful in vitiligo ...
Mohammad Amin Shahrbaf   +2 more
doaj   +1 more source

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