Results 21 to 30 of about 76,131 (358)

Melanocytes and Their Diseases [PDF]

Cold Spring Harbor Perspectives in Medicine, 2014
Human melanocytes are distributed not only in the epidermis and in hair follicles but also in mucosa, cochlea (ear), iris (eye), and mesencephalon (brain) among other tissues. Melanocytes, which are derived from the neural crest, are unique in that they produce eu-/pheo-melanin pigments in unique membrane-bound organelles termed melanosomes, which can ...
Vincent J. Hearing, Yuji Yamaguchi
openaire   +3 more sources

A Comparative Study on Photo-Protective and Anti-Melanogenic Properties of Different Kadsura coccinea Extracts

Plants, 2021
Kadsura coccinea (KC), a beneficial plant for human health, has been used for centuries in China, Thailand, and Korea in folk medicine and food. There is evidence supporting the biological effects of highly bioactive ingredients in KC such as lignans ...
Joong Suk Jeon, He Mi Kang, Ju Ha Park, Jum Soon Kang, Yong Jae Lee, Young Hoon Park, Byoung Il Je, Sun Young Park, Young Whan Choi   +8 more
doaj   +1 more source

Ocular manifestations of vitiligo: a systematic review

BMC Ophthalmology, 2023
Vitiligo is a disorder characterized by loss of epidermal melanocytes, resulting in depigmented macules and patches. While the relationship between ocular pathology and vitiligo has been demonstrated in conditions such as Vogt-Koyanagi-Harada and ...
Tessa LeWitt, Robert Tauscher, Gracious Obiofuma, Jonna Peterson, Ramez Haddadin, Roopal V. Kundu   +5 more
doaj   +1 more source

Type II Opsins in the Eye, the Pineal Complex and the Skin of Xenopus laevis: Using Changes in Skin Pigmentation as a Readout of Visual and Circadian Activity

Frontiers in Neuroanatomy, 2022
The eye, the pineal complex and the skin are important photosensitive organs. The African clawed frog, Xenopus laevis, senses light from the environment and adjusts skin color accordingly.
Gabriel E. Bertolesi, Nilakshi Debnath, Hannan R. Malik, Lawrence L. H. Man, Sarah McFarlane   +4 more
doaj   +1 more source

Melanocytic schwannoma [PDF]

Cancer, 1988
The clinical, histopathologic, immunohistochemical, and electron microscopic findings of two cases of melanocytic schwannoma are reported. One case, which occurred in the parotid gland, is believed to be the first reported in this location. The other case was located in the sacral spinal region.
Roberta M. Killeen, Carmel L. Davy Md and, Steven C. Bauserman   +2 more
openaire   +3 more sources

Melanoma Inhibitory Activity (MIA) Is Able to Induce Vitiligo-Like Depigmentation in an in vivo Mouse Model by Direct Injection in the Tail

Frontiers in Medicine, 2020
In the complex pathogenesis of vitiligo, the exact mechanism of the dermatosis is still to be clarified. We previously demonstrated that a protein called melanoma inhibitory activity (MIA) is present in non-segmental vitiligo skin and seems to cause the ...
Matteo Bordignon, Roberto Luisetto, Maria Luisa Valente, Marny Fedrigo, Chiara Castellani, Annalisa Angelini, Mauro Alaibac   +6 more
doaj   +1 more source

Melanocyte Function and Count of Leukotrichia in Vitiligo Using S100 Immunohistochemistry and Microphtalmia Associated Transcription Factor (MITF)

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2017
Background: Melanocyte of the hair follicle is one of the major sources of repigmentation in vitiligo. Leukotrichia is complete depigmentation with significant bleaching hair.
M. Yulianto Listiawan, Marina Rimadhani, Willy Sandhika   +2 more
doaj   +1 more source

Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway [PDF]

, 2009
Melanocortin-1 receptor (MC1R) and its ligands, a-melanocyte stimulating hormone (aMSH) and agouti signaling protein (ASIP), regulate switching between eumelanin and pheomelanin synthesis in melanocytes.
Abdel-Malek, Aberdam, Barsh, Bennett, Bennett, Bennett, Bertolotto, Buffey, Candille, Clément, Costin, Duhl, Englaro, Eves, Friedmann, García-Borrón, Graham, He, He, Hirobe, Ito, Ito, Ito, Ito, Jimbow, Land, Le Pape, Le Pape, Levy, McNulty, Millar, Mountjoy, Ollmann, Ozeki, Park, Robbins, Sakai, Sanchez-Mas, Slominski, Smalley, Sviderskaya, Sviderskaya, Sviderskaya, Sviderskaya, Tsatmali, Wakamatsu   +45 more
core   +2 more sources

An iterative genetic and dynamical modelling approach identifies novel features of the gene regulatory network underlying melanocyte development.

PLoS Genetics, 2011
The mechanisms generating stably differentiated cell-types from multipotent precursors are key to understanding normal development and have implications for treatment of cancer and the therapeutic use of stem cells.
Emma R Greenhill, Andrea Rocco, Laura Vibert, Masataka Nikaido, Robert N Kelsh   +4 more
doaj   +1 more source

Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour [PDF]

, 2016
The five-subunit WASH complex generates actin networks that participate in endocytic trafficking, migration and invasion in various cell types. Loss of one of the two subunits WASH or strumpellin in mice is lethal, but little is known about their role in
Insall, Robert H., Machesky, Laura M., Spence, Heather J., Strathdee, Douglas, Tyrrell, Benjamin J., Woodham, Emma F.   +5 more
core   +1 more source