Results 31 to 40 of about 78,152 (310)

Modulation of social behavior by the agouti pigmentation gene [PDF]

, 2014
Agouti is a secreted neuropeptide that acts as an endogenous antagonist of melanocortin receptors. Mice and rats lacking agouti (called non-agouti) have dark fur due to a disinhibition of melanocortin signaling and pigment deposition in the hair follicle.
Carola V, Gross CT, Novotny MV, Perlas E, Soini HA, Zonfrillo F   +5 more
core   +1 more source

circRNA18_46222157_46248185 inhibits melanogenesis by targeting miR-211/ pathway in goat melanocytes [PDF]

Animal Bioscience
Objective This study investigated the effects of circRNA18_46222157_46248185 (named circRNA18) on goat melanogenesis, which differs significantly in goat skins isolated from white and brown coat-colored skins.
Kai Yuan Ji, Xue Qing Zhang, Yi Wei Zhao, Chun E Liang, Xin Yuan, Yun Hai Zhang   +5 more
doaj   +1 more source

Obesity Induces Hypothalamic Endoplasmic Reticulum Stress and Impairs Proopiomelanocortin (POMC) Post-translational Processing [PDF]

, 2013
It was shown previously that abnormal prohormone processing or inactive proconverting enzymes that are responsible for this processing cause profound obesity.
Cakir, Isin, Cyr, Nicole E., Litvinov, Bogdan Patedakis, Nillni, Eduardo A., Perello, Mario, Romero, Amparo, Stuart, Ronald C.   +6 more
core   +1 more source

Gnaq and Gna11 in the Endothelin signaling pathway and melanoma

Frontiers in Genetics, 2016
In this article, we first briefly outline the function of G protein coupled receptors in cancer, and then specifically examine the roles of the seven transmembrane G protein coupled Endothelin B receptor (Ednrb) and the G proteins, GNAQ and GNA11, in ...
Oscar eUrtatiz, Catherine D Van Raamsdonk   +1 more
doaj   +1 more source

MicroRNAs in melanoma development and resistance to target therapy [PDF]

, 2017
microRNAs constitute a complex class of pleiotropic post-transcriptional regulators of gene expression involved in the control of several physiologic and pathologic processes.
Ascierto, Paolo Antonio, Ciliberto, Gennaro, Costantini, Susan, Croce, Carlo M, Fattore, Luigi, Malpicci, Debora, Mancini, Rita, Ruggiero, Ciro Francesco   +7 more
core   +1 more source

Frontiers in Pigment Cell and Melanoma Research

, 2018
We identify emerging frontiers in clinical and basic research of melanocyte biology and its associated biomedical disciplines. We describe challenges and opportunities in clinical and basic research of normal and diseased melanocytes that impact current ...
Birlea, Stanca, Bosenberg, Marcus W., Box, Neil F., Brash, Douglas, Cassidy, Pamela B., Chen, Suzie, D'Orazio, John August, Filipp, Fabian V., Fujita, Mayumi, Goh, Boon-Kee, Herlyn, Meenhard, Indra, Arup K., Larue, Lionel, Leachman, Sancy A., Liu-Smith, Feng, Manga, Prashiela, Montoliu, Lluis, Norris, David A., Poole, Caroline Le, Shellman, Yiqun, Smalley, Keiran S. M., Spritz, Richard A., Sturm, Richard A., Swetter, Susan M., Terzian, Tamara, Wakamatsu, Kazumasa, Weber, Jeffrey S.   +26 more
core   +1 more source

p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis. [PDF]

, 2013
The role of apoptosis in melanoma pathogenesis and chemoresistance is poorly characterized. Mutations in TP53 occur infrequently, yet the TP53 apoptotic pathway is often abrogated.
Akslen, Albino, Anissa Chikh, Antonio Costanzo, Arima, Arnoult, Avery-Kiejda, Avery-Kiejda, Azzola, Bae, Baisden, Bardeesy, Belmar-Lopez, Benchimol, Bourne, Brinck, Burford, Bártek, Catherine A. Harwood, Chan, Charlotte M. Proby, Chehab, Chipuk, Chipuk, Choi, Colombari, Daniele Bergamaschi, David Mesher, Dellavalle, Dhillon, Di Como, Dotto, el-Deiry, Fenouille, Flores, Flores, Francesca Moretti, Fukushima, Gembarska, Giovanna Chiorino, Glusac, Gomez-Monterrey, Gressner, Hameed, Harmes, Hibi, Hirao, Hocker, Hoek, Houben, Hu, Hussein, Ikawa, Irene M. Leigh, Jacobs, Ji, Kakudo, Kanner, Kanoko, Karst, Katoh, Keyes, Kilic, Knopf, Koga, Koster, Kulesz-Martin, Lassam, Leverrier, Li, Liefer, Little, MacPartlin, Mancini, Mangiulli, Manuela Graf, Marchenko, Marchini, Maria Scatolini, Massion, Matsuoka, McGregor, Merlino, Michaelis, Mihara, Mills, Moll, Morgan, Mundt, Muthusamy, Müller, Narahashi, Nemajerova, Oda, Okada, Osada, Paolo Sanza’, Perez-Losada, Petitjean, Polsky, Prince, Reis-Filho, Reis-Filho, Ribeiro-Silva, Riley, Rino Cerio, Rocca, Rocco, Rubeta N. Matin, Sakiz, Sansome, Sato, Satyamoorthy, Scatolini, Schilling, Seitz, Senoo, Senoo, Serber, Shieh, Shields, Smalley, Sparrow, Stephanie Law Pak Chong, Stretch, Suh, Tokuyasu, Tuve, Valentina Senatore, Vance, Verhaegen, Walerych, Walerych, Weiss, Westfall, Whitesell, Wäster, Yamamoto, Yamamoto, Yang, Yang, Yaziji, Zangen, Zerp   +143 more
core   +1 more source

Molecular and cellular pathogenesis of melanoma initiation and progression [PDF]

, 2013
Melanoma is a malignant tumour of melanocytes, which can spread to other organs of the body resulting in severe and/or lethal malignancies. Melanocytes are pigment producing cells found in deep layer of the epidermis and are originated from melanocytes ...
Regad, T
core   +1 more source

Recurrent laryngeal neuropathy secondary to nerve compression by melanomas - case report [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Recurrent laryngeal neuropathy (RLN) etiology can be acquired, iatrogenic or idiopathic. There are no previous reports of RLN caused by recurrent laryngeal nerve compression by melanomas.
J.M. Alonso, G.S. Rosa, A. Hataka, C.A. Hussni, M.L. Conceição, M.J. Watanabe, C.A. Rodrigues, A.L.G. Alves   +7 more
doaj   +2 more sources

A Comparative Study on Photo-Protective and Anti-Melanogenic Properties of Different Kadsura coccinea Extracts

Plants, 2021
Kadsura coccinea (KC), a beneficial plant for human health, has been used for centuries in China, Thailand, and Korea in folk medicine and food. There is evidence supporting the biological effects of highly bioactive ingredients in KC such as lignans ...
Joong Suk Jeon, He Mi Kang, Ju Ha Park, Jum Soon Kang, Yong Jae Lee, Young Hoon Park, Byoung Il Je, Sun Young Park, Young Whan Choi   +8 more
doaj   +1 more source