Results 31 to 40 of about 92,933 (386)

A Comparison Between Phorbol 12 Myristate 13 Acetate and Phorbol 12, 13 Dibutyrate in Human Melanocyte Culture [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Melanocyte culture is an integral part of the studies of skin biology and cosmetic applications. After the introduction of selective medium for the culture of human melanocyte using Phorbol 12-myristate13-acetate (PMA) in 1982, a lot of ...
Divya Padma, Kumar M.R. Bhat
doaj   +1 more source

Super-High Magnification Dermoscopy in 190 Clinically Atypical Pigmented Lesions

Diagnostics, 2023
Super-high (×400) magnification dermoscopy (D400) is a new non-invasive imaging technique that has been shown to add information for the differential diagnosis of melanocytic lesions in a pilot study.
Elisa Cinotti, Vittoria Cioppa, Linda Tognetti, Jean Luc Perrot, Renato Rossi, Matteo Gnone, Alessandra Cartocci, Pietro Rubegni, Giulio Cortonesi   +8 more
doaj   +1 more source

An iterative genetic and dynamical modelling approach identifies novel features of the gene regulatory network underlying melanocyte development.

PLoS Genetics, 2011
The mechanisms generating stably differentiated cell-types from multipotent precursors are key to understanding normal development and have implications for treatment of cancer and the therapeutic use of stem cells.
Emma R Greenhill, Andrea Rocco, Laura Vibert, Masataka Nikaido, Robert N Kelsh   +4 more
doaj   +1 more source

Hyperactivation of Sympathetic Nerves Drives Melanocyte Stem Cell Depletion

Nature, 2019
Empirical and anecdotal evidence has associated stress with accelerated hair greying (formation of unpigmented hairs) 1 , 2 , but so far there has been little scientific validation of this link.
Bing Zhang, Sai Ma, I. Rachmin, Megan He, P. Baral, Sekyu Choi, W. Gonçalves, Y. Shwartz, E. Fast, Yiqun Su, L. Zon, A. Regev, Jason D. Buenrostro, Thiago M. Cunha, I. Chiu, D. Fisher, Y. Hsu   +16 more
semanticscholar   +1 more source

Innate lymphocyte-induced CXCR3B-mediated melanocyte apoptosis is a potential initiator of T-cell autoreactivity in vitiligo

Nature Communications, 2019
T-cells play a crucial role in progression of autoimmunity, including vitiligo, yet the initial steps triggering their activation and tissue damage remain unknown.
M. Tulic, E. Cavazza, Y. Cheli, A. Jacquel, C. Luci, N. Cardot-Leccia, Hanene Hadhiri-Bzioueche, P. Abbe, M. Gesson, L. Sormani, Claire Regazzetti, G. Beranger, Cédric Lerévérend, Caroline Pons, A. Khemis, R. Ballotti, C. Bertolotto, S. Rocchi, T. Passeron   +18 more
semanticscholar   +1 more source

Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation [PDF]

, 2013
Fascins, a family of actin-bundling proteins, are expressed in a spatially and temporally restricted manner during development and often in cancer.
Ackermann, Adams, Adams, Aratyn, Baxter, Borghese, Bravo-Cordero, Breitsprecher, Cant, Colombo, De Arcangelis, Delmas, Gillespie, Harris, Hashimoto, Hashimoto, Hashimoto, Hayashi, Hornyak, Jawhari, Jayo, Jayo, Jordan, Kim, Larue, Li, Li, Li, Lindsay, Loughna, Luciani, Machesky, Mackenzie, Migeotte, Mort, Nagy, Novak, Pelosi, Pla, Schoumacher, Sherr, Silver, Takemoto, Uyama, Vignjevic, Wang, Woolner, Xie, Xie, Yamakita, Yamakita, Yamashiro, Zanet   +52 more
core   +2 more sources

SIRT3-Dependent Mitochondrial Dynamics Remodeling Contributes to Oxidative Stress-Induced Melanocyte Degeneration in Vitiligo

Theranostics, 2019
Mitochondrial dysregulation has been implicated in oxidative stress-induced melanocyte destruction in vitiligo. However, the molecular mechanism underlying this process is merely investigated. Given the prominent role of nicotinamide adenine dinucleotide
X. Yi, Weinan Guo, Qiong Shi, Yuqi Yang, Weigang Zhang, Xuguang Chen, P. Kang, Jiaxi Chen, Tingting Cui, Jinyuan Ma, Huina Wang, Sen Guo, Yuqian Chang, Ling Liu, Z. Jian, Lin Wang, Qian Xiao, Shuli Li, T. Gao, Chunying Li   +19 more
semanticscholar   +1 more source

In vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cells [PDF]

, 2015
Oncogenic signaling in melanocytes results in oncogene-induced senescence (OIS), a stable cell-cycle arrest frequently characterized by a bi- or multinuclear phenotype that is considered as a barrier to cancer progression.
Bröcker, E.-B., Haferkamp, S., Hufnagel, A.L., Kneitz, S., Leikam, C., Meierjohann, S., Murphy, D.J., Mühling, B., Nanda, I., Otto, C., Schartl, M., Schmid, M., Wagner, T.U.   +12 more
core   +2 more sources

The First Live-Cell Based Product in The Iranian Drug List; ReColorCell® [PDF]

Cell Journal, 2023
Vitiligo is an autoimmune skin disorder that can significantly affect the quality of life in patients. However, currenttreatment strategies such as phototherapy, topical glucocorticosteroids, or systemic immunosuppressants canbe helpful in vitiligo ...
Mohammad Amin Shahrbaf, Leila Ataei Fashtami, Massoud Vosough   +2 more
doaj   +1 more source

Melanocytes are selectively vulnerable to UVA-mediated bystander oxidative signaling. [PDF]

, 2014
Long-wave UVA is the major component of terrestrial UV radiation and is also the predominant constituent of indoor sunlamps, both of which have been shown to increase cutaneous melanoma risk.
Rajadurai, A, Redmond, RW, Sviderskaya, EV, Tsao, H, Udayakumar, D   +4 more
core   +2 more sources