Results 61 to 70 of about 62,888 (340)

Designing the Next Generation of Biomaterials through Nanoengineering

Advanced Materials, EarlyView.
Nanoengineering enables precise control over biomaterial interactions with living systems by tuning surface energy, defects, porosity, and crystallinity. This review highlights how these nanoscale design parameters drive advances in regenerative medicine, drug delivery, bioprinting, biosensing, and bioimaging, while outlining key translational ...
Ryan Davis Jr., Ishaan Duggal, Nicholas A. Peppas, Akhilesh K. Gaharwar   +3 more
wiley   +1 more source

A Simple Drug Delivery System for Platelet-Derived Bioactive Molecules, to Improve Melanocyte Stimulation in Vitiligo Treatment

Nanomaterials, 2020
Vitiligo is the most common depigmentation disorder of the skin. Currently, its therapy focuses on the halting of the immune response and stimulation of the regenerative processes, leading to the restoration of normal melanocyte function.
Karolina Vocetkova, Vera Sovkova, Matej Buzgo, Vera Lukasova, Radek Divin, Michala Rampichova, Pavel Blazek, Tomas Zikmund, Jozef Kaiser, Zdenek Karpisek, Evzen Amler, Eva Filova   +11 more
doaj   +1 more source

Identification of a Potentially Functional circRNA-miRNA-mRNA Regulatory Network in Melanocytes for Investigating Pathogenesis of Vitiligo

Frontiers in Genetics, 2021
CircRNAs have been reported to play essential roles in regulating immunity and inflammation, which may be an important regulatory factor in the development of vitiligo.
Lili Li, Zhi Xie, Xiliang Qian, Tai Wang, Minmin Jiang, Jinglin Qin, Chen Wang, Rongqun Wu, Canling Song   +8 more
doaj   +1 more source

A modelling approach towards Epidermal homoeostasis control

, 2007
In order to grasp the features arising from cellular discreteness and individuality, in large parts of cell tissue modelling agent-based models are favoured.
Barthel, Bashir, Bauer, Benoit, Bettelheim, Brilliantov, Byrne, Carvalho, Chenevert, Chu, Cickovski, Dallon, Dormann, Drasdo, Drasdo, Edelsbrunner, Ferreira, Fletcher, Freyer, Freyer, Galle, Galle, Gardner, Gatenby, Gernot Schaller, Gershenfeld, Graner, Hertz, Hoath, Johnson, Johnson, Joos, Kasting, Kreft, Kreft, Kreft, Landau, Livingston, Louzoun, Mahaffy, Maniotis, Meineke, Meyer-Hermann, Michael Meyer-Hermann, Montagna, Moy, Newman, Norlen, Picioreanu, Potten, Press, Savill, Schaller, Schaller, Schaller, Schwindt, Smolle, Tang, Tuchin, Turner, Verdier, von Neumann, Wehrle, Weliky, Weliky   +64 more
core   +1 more source

Biology of melanocytes in mammals

Frontiers in Cell and Developmental Biology, 2023
Melanocytes, which originate from the neuroectoderm, are specialized cells responsible for producing pigments and possessing a dendritic morphology. These cells migrate to the epidermis and follicles, contributing to skin and hair pigmentation during embryonic development.
Ying-Zhe Cui, Xiao-Yong Man
openaire   +3 more sources

Evolution of Ocular Organ‐On‐Chip Systems for Disease Modelling and Drug Testing: Where are We Now?

Advanced Therapeutics, EarlyView.
The rise in ophthalmic diseases due to aging, screen use, and environmental factors has driven demand for better ocular models. Traditional systems fall short, encouraging the development of organ‐on‐chip devices. These microfluidic platforms replicate eye tissue architecture, enable drug screening, and simulate ocular diseases.
Sara Trujillo
wiley   +1 more source

Identification of Melanin in the Mantle of the Pacific Oyster Crassostrea gigas

Frontiers in Marine Science, 2022
The Pacific oyster, Crassostrea gigas, is widely distributed and is substantially important to shellfish cultivation. Oysters with melanin-colored shells and soft parts are increasingly popular and are of high economic value.
Yijing Han, Chaoyi Xie, Nini Fan, Hongce Song, Xiaomei Wang, Yanxin Zheng, Meiwei Zhang, Yaqiong Liu, Baoyu Huang, Lei Wei, Xiaotong Wang   +10 more
doaj   +1 more source

Obesity Induces Hypothalamic Endoplasmic Reticulum Stress and Impairs Proopiomelanocortin (POMC) Post-translational Processing [PDF]

, 2013
It was shown previously that abnormal prohormone processing or inactive proconverting enzymes that are responsible for this processing cause profound obesity.
Cakir, Isin, Cyr, Nicole E., Litvinov, Bogdan Patedakis, Nillni, Eduardo A., Perello, Mario, Romero, Amparo, Stuart, Ronald C.   +6 more
core   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

Melanocyte progenitor cells reside in human subcutaneous adipose tissue.

PLoS ONE, 2021
Based on the assumption that some progenitor cells in an organ might reside in neighboring adipose tissue, we investigated whether melanocyte progenitor cells reside in human subcutaneous adipose tissue.
Yuri Ikeda, Akino Wada, Toshio Hasegawa, Mutsumi Yokota, Masato Koike, Shigaku Ikeda   +5 more
doaj   +1 more source