Results 181 to 190 of about 85,786 (342)
A novel approach to target skin photodamage: Topical application of salt inducible kinase inhibitors
UV‐induced photodamage leads to increased DNA damage and elevated MMP levels, which degrade collagen and contribute to wrinkle formation. SLT‐001 and SLT‐008, novel cosmetic ingredients that target salt‐inducible kinase, help reverse this effect by enhancing DNA repair, reducing MMP expression and decreasing erythema, thereby mitigating photodamage ...
Inbal Rachmin+7 more
wiley +1 more source
Melanocytes and photosensory organs share a common ancestry that illuminates the origins of the neural crest. [PDF]
Fatieieva Y+5 more
europepmc +1 more source
The Role of Stromal Tumor Environment in Advancing Skin Cancer Diagnosis and Treatment
ABSTRACT The stromal tumor environment (STE) plays a vital yet often underrecognized role in cancer progression, shaping tumor development. It influences complex interactions among stromal cells, immune cells, extracellular matrix (ECM) components, and signaling molecules.
Frank Jing+3 more
wiley +1 more source
Specific oncogene activation of the cell of origin in mucosal melanoma. [PDF]
Babu S+22 more
europepmc +1 more source
Melanoma cells secrete follistatin, an antagonist of activin-mediated growth inhibition [PDF]
Bracke, Marc+5 more
core +2 more sources
ABSTRACT The incidence of melanoma is increasing worldwide, requiring early detection to improve survival rates. Although dermoscopy is the standard non‐invasive tool for diagnosing melanoma, it relies on experience and skill. Advances in optical imaging technologies and artificial intelligence have the potential to improve diagnostic accuracy.
Noémi Nóra Varga+8 more
wiley +1 more source
Melanocyte dysfunctions: future and promise of stem cells. [PDF]
Ali SA, Kassab G, Husain T.
europepmc +1 more source