Results 181 to 190 of about 116,555 (410)

Requirements for Alternative In Vitro and In Silico Skin Models of Irritant and Allergic Contact Dermatitis

Contact Dermatitis, EarlyView.
ABSTRACT Contact dermatitis is an inflammatory disease characterised by skin redness and swelling, oozing of fluid or pus and pain, caused by direct skin contact with an irritant or allergen. Its prevalence has skyrocketed worldwide, probably because human skin is in daily contact with an increasing gamut of irritants and allergens, which should ...
Meital Portugal‐Cohen, Warangkana Lohcharoenkal, Evelyn Kelemen, Inge Kortekaas Krohn, Shauni De Vriese, Danuta Gutowska‐Owsiak, Ivone Jakasa, Dijana Furundžić, Anna Zalewska‐Janowska, Sandrine Dubrac   +9 more
wiley   +1 more source

New Anti‐Fibrotic Strategies for Keloids: Insights From Single‐Cell Multi‐Omics

Cell Proliferation, EarlyView.
Our research not only revealed the ubiquity and activity of POSTN‐positive mesenchymal fibroblasts in keloids but also discovered the predominant role of IGFBP2‐positive fibroblasts in normal skin and their potential significance in the process of anti‐fibrotic therapy.
Songyun Zhao, Jiaheng Xie, Qian Zhang, Tianyi Ni, Jinde Lin, Weicheng Gao, Liping Zhao, Min Yi, Liying Tu, Pengpeng Zhang, Dan Wu, Qikai Tang, Chenfeng Ma, Yucang He, Liqun Li, Guoping Wu, Wei Yan   +16 more
wiley   +1 more source

Dermoscopy Assisting Diagnosis of Dermal Melanocytosis Limited to the Hand [PDF]

Clin Case Rep
ABSTRACT Acquired dermal melanocytosis (ADM) is a skin disorder characterized by the presence of melanocytes in the dermis. The face is the most common site of ADM. ADM can be difficult to diagnose when it occurs in an unusual clinical setting.
Huang M, Huang W, Wang C, Li Q, Qin G.
europepmc   +2 more sources

Neural crest induction in Xenopus: evidence for a two-signal model [PDF]

, 1998
We have investigated the molecular interactions underlying neural crest formation in Xenopus. Using chordin overexpression to antagonize endogenous BMP signaling in whole embryos and explants, we demonstrate that such inhibition alone is insufficient to ...
Bronner-Fraser, Marianne, LaBonne, Carole   +1 more
core  

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Mechanism underlying synergic activation of Tyrosinase promoter by MITF and IRF4 [PDF]

, 2017
Background: The transcription factor interferon regulatory factor 4 (IRF4) was identified to be involved in human pigmentation by genome-wide association studies (GWASs).
Cai, Xinzhang, Chen, Hongsheng, Feng, Yong, He, Chufeng, Li, Jiada, Liu, Huadie, Liu, Xueming, Liu, Yalan, Mei, Lingyun, Peng, Zhen, Song, Jian, Vleminckx, Kris   +11 more
core   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan, Zhou Chen, Yuhua Zhang, Wenjie Sun, Lifei Li, Xia Huang   +5 more
wiley   +1 more source

Fundamental hair follicle biology and fine fibre production in animals

Animal, 2010
Hair ‘fine’ fibre is an important commercial product of farmed and certain wild animal species. The fibre is produced in follicles embedded in skin. These have properties in common with other tissues of the integument and have importance in determining ...
H. Galbraith
doaj  

Identification of α- and β-Melanocyte-Stimulating Hormone in Hog Posterior Pituitary Powder

, 1958
Teh H. Lee
openalex   +1 more source

Bioprinting of biomimetic skin containing melanocytes

Experimental Dermatology, 2018
D. Min, Wonhye Lee, I. Bae, T. R. Lee, Phillip Croce, S. Yoo   +5 more
semanticscholar   +1 more source