Results 61 to 70 of about 123,035 (391)
Skin melanocytes: biology and development
Advances in Dermatology and Allergology, 2013 In the human skin, melanocytes are present in the epidermis and hair follicles. The basic features of these cells are the ability to melanin production and the origin from neural crest cells.
M. Cichorek +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Antioxidants, 2021 Exposure to sun and especially to ultraviolet radiation (UVR) exerts well known detrimental effects on skin which are implicated in malignancy. UVR induces production of cyclobutane pyrimidine dimers (CPDs), immediately during exposure and even hours ...
Mikel Portillo-Esnaola +6 more
doaj +1 more source
Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis. [PDF]
, 2019 Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic ...
Hao, Hongyan +4 more
core +2 more sources
Acta Dermato-Venereologica, 2015 Increased expression of the cytokine interferon (IFN)-γ plays a pivotal role in vitiligo-induced depigmentation. However, the major source of IFN-γ in vitiligo patients and the mechanisms underlying melanocyte destruction are unknown.
Lili Yang +6 more
semanticscholar +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Shedding light on melanins within in situ human eye melanocytes using 2-photon microscopy profiling techniques. [PDF]
, 2019 Choroidal melanocytes (HCMs) are melanin-producing cells in the vascular uvea of the human eye (iris, ciliary body and choroid). These cranial neural crest-derived cells migrate to populate a mesodermal microenvironment, and display cellular functions ...
Cherepanoff, Svetlana +6 more
core
Bio‐Friendly Artificial Muscles Based on Carbon Nanotube Yarns and Eutectogel Derivatives
Advanced Functional Materials, EarlyView.Solid‐state artificial muscles based on coiled commercial carbon nanotube yarns coated with eutectogel derivatives exhibit unipolar actuation through selective ion intercalation. Combining polyanionic and polycationic gels enables enhanced contractile stroke and high energy density.
Gabriela Ananieva +6 more
wiley +1 more source
Differentiation of cultured hair follicle neural crest stem cells into functional melanocytes
HeliyonMany autologous melanocytes are required for surgical treatment of depigmentation diseases such as vitiligo. However, primary cultured melanocytes have a limited number of in vitro passages.
Hongjuan Wang +7 more
doaj +1 more source
Primary oral malignant melanoma: Clinicopathological series of four cases
Dental Research Journal, 2012 Melanoma of the oral cavity is a rare malignant disease. On account of the presence at relatively obscure areas in the oral cavity, most of oral malignant melanomas are diagnosed at a late stage.
Ajay Kumar +3 more
doaj +1 more source