Results 61 to 70 of about 116,555 (410)

Aspirin induces Nrf2‐mediated transcriptional activation of haem oxygenase‐1 in protection of human melanocytes from H2O2‐induced oxidative stress

open access: yesJournal of Cellular and Molecular Medicine, 2016
The removal of hydrogen peroxide (H2O2) by antioxidants has been proven to be beneficial to patients with vitiligo. Aspirin (acetylsalicylic acid, ASA) has antioxidant activity and has great preventive and therapeutical effect in many oxidative stress ...
Z. Jian   +8 more
semanticscholar   +1 more source

Interferon-gamma Inhibits Melanogenesis and Induces Apoptosis in Melanocytes: A Pivotal Role of CD8+ Cytotoxic T Lymphocytes in Vitiligo.

open access: yesActa Dermato-Venereologica, 2015
Increased expression of the cytokine interferon (IFN)-γ plays a pivotal role in vitiligo-induced depigmentation. However, the major source of IFN-γ in vitiligo patients and the mechanisms underlying melanocyte destruction are unknown.
Lili Yang   +6 more
semanticscholar   +1 more source

Association between melanocytic neoplasms and seborrheic keratosis: more than a coincidental collision?

open access: yesDermatology Practical & Conceptual, 2012
Clinical observations and an expanding knowledge of cell-to-cell communication have led us to speculate that the finding of a melanocytic nevus in conjunction with a seborrheic keratosis is more than a coincidental collision of two lesions.
Jennifer DeFazio   +4 more
doaj   +1 more source

Treatment of stable vitiligo using cultured and non-cultured autologous melanocytes from hair follicle outer root sheath cell suspension

open access: yesJournal of the Egyptian Women’s Dermatologic Society, 2020
Background Several surgical treatment methods have been proposed for the treatment of stable vitiligo, but they remain inadequate in terms of patient satisfaction.
Heba A Gad   +4 more
doaj   +1 more source

Melanocytes as Instigators and Victims of Oxidative Stress

open access: yesJournal of Investigative Dermatology, 2014
Epidermal melanocytes are particularly vulnerable to oxidative stress due to the pro-oxidant state generated during melanin synthesis, and to intrinsic antioxidant defences that are compromised in pathologic conditions.
Laurence Denat   +4 more
semanticscholar   +1 more source

Human cutaneous interfollicular melanocytes differentiate temporarily under genotoxic stress

open access: yesiScience, 2022
Summary: DNA-damage response of cutaneous interfollicular melanocytes to fractionated radiotherapy was investigated by immunostaining of tissue sections from punch biopsies collected before, during, and after the treatment of patients for breast cancer ...
Per Fessé   +5 more
doaj  

A Comparative Analysis of Transfer Learning-based Techniques for the Classification of Melanocytic Nevi [PDF]

open access: yesarXiv, 2022
Skin cancer is a fatal manifestation of cancer. Unrepaired deoxyribo-nucleic acid (DNA) in skin cells, causes genetic defects in the skin and leads to skin cancer. To deal with lethal mortality rates coupled with skyrocketing costs of medical treatment, early diagnosis is mandatory.
arxiv  

The usefulness of c-Kit in the immunohistochemical assessment of melanocytic lesions [PDF]

open access: yes, 2011
C-Kit (CD117), the receptor for the stem cell factor, a growth factor for melanocyte migra- tion and proliferation, has shown differential immunostaining in various benign and malig- nant melanocytic lesions. The purpose of this study is to compare c-Kit
Atzori L   +9 more
core   +1 more source

Melanocyte Mitogens Induce Both Melanocyte Chemokinesis and Chemotaxis

open access: yesJournal of Investigative Dermatology, 1995
It is believed that during repigmentation of vitiligo, inactive melanocytes in the outer root sheath of the hair follicle become activated, proliferate, and migrate into the depigmented skin. However, the mechanisms controlling melanocyte migration remain to be elucidated.
Jeffrey B. Travers   +5 more
openaire   +3 more sources

Liquid Crystalline Networks Hamper the Malignancy of Cancer Cells

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Liquid Crystalline Networks are used as scaffolds for the growth of A375 melanoma cells demonstrating to affect their malignancy. Indeed, only by contact, these materials reduces cell proliferation and colony formation capacity, while increasing the number of senescent cells and promoting the mesenchymal to epithelial transition.
Daniele Martella   +9 more
wiley   +1 more source

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