Results 61 to 70 of about 29,468 (254)

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

What controls melanogenesis? [PDF]

open access: yesExperimental Dermatology, 1998
The pigments eumelanin and pheomelanin are the visually most striking products of specialized neural crest‐derived cells (melanocytes), and provide color to both epidermis and hair shafts. While the intriguing and controversial biological functions of these multifaceted heteropolymers will be discussed in a later feature, here it is explored how their ...
K, Schallreuter   +4 more
openaire   +2 more sources

Occupational Exposure to Factory‐Derived Particulate Matter 2.5 Induces Cutaneous Toxicity in Workers and HaCaT Keratinocytes Through Oxidative Stress and Inflammation

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT This study aimed to evaluate the toxicological effects of occupational exposure to factory‐derived particulate matter (PM2.5) on human skin, emphasizing its role as a potential target organ of environmental toxicants. An epidemiological survey comparing factory and nonfactory workers was conducted by assessing their skin elasticity and color ...
Miku Tanaka   +7 more
wiley   +1 more source

ENZYME LOCALIZATION DURING MELANOGENESIS [PDF]

open access: yesThe Journal of Cell Biology, 1969
The DOPA-reaction was used to identify tyrosinase in the nucleus and cytoplasm of the neural crest melanoblast of Taricha torosa, the California newt. In this urodele there is a nuclear DOPA-positive response during the normal embryonic development from the late blastula stage to the nucleus of the early melanocyte.
openaire   +2 more sources

Comparative Evaluation of R134a and HFO‐1234ze Cryogen Spray Cooling Using a Mouse Model With Controllable Epidermal Pigmentation

open access: yesLasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives Cryogen spray cooling (CSC) is critical for protecting the epidermis during laser dermatologic procedures. The widely used cryogen, R134a, has a high global warming potential (GWP), motivating interest in environmentally favorable alternatives such as HFO‐1234ze.
Wangcun Jia   +13 more
wiley   +1 more source

Neobavaisoflavone Inhibits Melanogenesis through the Regulation of Akt/GSK-3β and MEK/ERK Pathways in B16F10 Cells and a Reconstructed Human 3D Skin Model

open access: yesMolecules, 2020
Previous studies have confirmed the anti-melanogenic effect of the aerial part of Pueraria lobata, however, due to its inherent color, P. lobata has limited commercial use. In this study, an extract (GALM-DC) of the aerial part of P.
Da Eun Kim   +4 more
doaj   +1 more source

Melanoma, Melanin, and Melanogenesis: The Yin and Yang Relationship

open access: yesFrontiers in Oncology, 2022
Melanin pigment plays a critical role in the protection against the harmful effects of ultraviolet radiation and other environmental stressors. It is produced by the enzymatic transformation of L-tyrosine to dopaquinone and subsequent chemical and ...
Radomir M. Slominski   +6 more
doaj   +1 more source

A rare case of melanosis of the hard palate mucosa in a patient with chronic myeloid leukemia [PDF]

open access: yes, 2015
Imatinib Mesylate, also known as Gleevec or ST1-571, is a tyrosine-kinase inhibitor used as the gold standard medication for the chronic myeloid leukemia (CML); Imatinib has indeed deeply revolutionized the CML therapy allowing most patients to have a ...
Bosco, Daniela   +4 more
core   +3 more sources

Bridging Psychological Stress and Skin Cellular Aging: Flavonoids as a Dual‐Action Therapeutic Strategy

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte   +3 more
wiley   +1 more source

Identification of Anti-Melanogenesis Constituents from Morus alba L. Leaves

open access: yesMolecules, 2018
The individual parts of Morus alba L. including root bark, branches, leaves, and fruits are used as a cosmetic ingredient in many Asian countries. This study identified several anti-melanogenesis constituents in a 70% ethanol extract of M.
Hong Xu Li   +7 more
doaj   +1 more source

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