Results 61 to 70 of about 11,542 (237)
Melanopsin signalling in mammalian iris and retina [PDF]
Nature, 2011 Non-mammalian vertebrates have an intrinsically photosensitive iris and thus a local pupillary light reflex (PLR). In contrast, it is thought that the PLR in mammals generally requires neuronal circuitry connecting the eye and the brain. Here we report that an intrinsic component of the PLR is in fact widespread in nocturnal and crepuscular mammals. In
Xue, T. +15 more
openaire +3 more sources
Traceless Regulation of Genetic Circuitry
Advanced Science, EarlyView.Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley +1 more source
Frontiers in Cellular Neuroscience, 2018 Intrinsically photosensitive retinal ganglion cells (ipRGCs) mediate not only image-forming vision like other ganglion cells, but also non-image-forming physiological responses to light such as pupil constriction and circadian photoentrainment.
Melanie M. Schroeder +12 more
doaj +1 more source
eLife, 2023 Melanopsin signaling within intrinsically photosensitive retinal ganglion cell (ipRGC) subtypes impacts a broad range of behaviors from circadian photoentrainment to conscious visual perception.
Ely Contreras +4 more
doaj +1 more source
Distribution of melanopsin positive neurons in pigmented and albino mice: evidence for melanopsin interneurons in the mouse retina. [PDF]
, 2014 Here we have studied the population of intrinsically photosensitive retinal ganglion cells (ipRGCs) in adult pigmented and albino mice. Our data show that although pigmented (C57Bl/6) and albino (Swiss) mice have a similar total number of ipRGCs, their ...
Agudo-Barriuso, M +8 more
core
Medical management of hereditary optic neuropathies. [PDF]
, 2014 Hereditary optic neuropathies are diseases affecting the optic nerve. The most common are mitochondrial hereditary optic neuropathies, i.e., the maternally inherited Leber's hereditary optic neuropathy (LHON) and dominant optic atrophy (DOA).
Barboni, Piero +4 more
core +1 more source
Extraocular Photoreception in Optic Lobes, Suckers, and Skin of Octopus vulgaris
Integrative Zoology, EarlyView.Evidence of extra‐ocular photoreception in Octopus vulgaris (a) Diagram of the O. vulgaris different tissues considered: SPB, sucker proximal big; SPL, sucker proximal large; SM, sucker medium; SD, sucker distal; SK, skin; OL, optic lobes; RT, retina; (b‐d) Gene expression analysis of Ov‐GRK1 (red), Ov‐retinochrome (green), Ov‐rhodopsin (blue) mRNA ...
Valeria Maselli +7 more
wiley +1 more source
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary The interplay of daily life factors, including mood, physical activity, or light exposure, influences sleep architecture and quality. Laboratory‐based studies often isolate these determinants to establish causality, thereby sacrificing ecological validity.
Anna M. Biller +8 more
wiley +1 more source
Alerting or Somnogenic Light: Pick Your Color. [PDF]
, 2016 In mammals, light exerts pervasive effects on physiology and behavior in two ways: indirectly through clock synchronization and the phase adjustment of circadian rhythms, and directly through the promotion of alertness and sleep, respectively, in diurnal
Bourgin, P., Hubbard, J.
core +3 more sources
Robust visual cortex evoked potentials (VEP) in Gnat1 and Gnat2 knockout mice
Frontiers in Cellular Neuroscience, 2022 Intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment melanopsin, imparting to themselves the ability to respond to light in the absence of input from rod or cone photoreceptors.
Michael D. Flood +6 more
doaj +1 more source