Results 71 to 80 of about 11,542 (237)

The Effects of Neurosteroids, such as Pregnenolone Sulfate and its receptor, TrpM3 in the Retina. [PDF]

open access: yes, 2019
Pregnenolone sulfate (PregS) is the precursor to all steroid hormones and is produced in neurons in an activity dependent manner. Studies have shown that PregS production is upregulated during certain critical periods of development, such as in the first
Webster, Corey Michael
core  

A Method to Evaluate the Stimulation of a Real World Field of View by Means of a Spectroradiometric Analysis [PDF]

open access: yes, 2015
Stimulation elicited by a real world field of view is related to the color, the intensity and the direction of the information reaching the eye: different spectral power distributions of light trigger different responses. An evaluation of the stimulation
Barbalace, Monica   +7 more
core   +2 more sources

Melanopsin Stimulation Modulates Blackness Induction

open access: yesColor Research &Application, Volume 51, Issue 1, January/February 2026.
Spectral power distributions of (A) the surround and (B) the center stimuli. The stimulus intensity to melanopsin cells of the surround was modulated from 0.51 to 1.21 (#1; 0.51, #2; 0.65, #3; 0.78, #4; 0.93, #5; 1.09, #6; 1.21, #7; 0.51, #8; 0.67, #9; 0.95, #10; 1.21) in the melanopic/photopic ratio (M/P ratio) under both the 700 cd/m2 and 375 cd/m2 ...
Masahiko Yamakawa   +2 more
wiley   +1 more source

Melanopsin Driven Light Responses Across a Large Fraction of Retinal Ganglion Cells in a Dystrophic Retina

open access: yesFrontiers in Neuroscience, 2020
Intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment melanopsin and project to central targets, allowing them to contribute to both image-forming and non-image forming vision.
Cyril G. Eleftheriou   +5 more
doaj   +1 more source

Evolution and functional characterisation of melanopsins in a deep-sea chimaera (elephant shark, Callorhinchus milii). [PDF]

open access: yesPLoS ONE, 2012
Non-visual photoreception in mammals is primarily mediated by two splice variants that derive from a single melanopsin (OPN4M) gene, whose expression is restricted to a subset of retinal ganglion cells.
Wayne I L Davies   +9 more
doaj   +1 more source

Reduced Neuronal Self‐Avoidance in Mouse Starburst Amacrine Cells With Only One Pcdhg Isoform

open access: yesDevelopmental Neurobiology, Volume 86, Issue 1, January 2026.
ABSTRACT The clustered protocadherins (cPcdhs) are a family of ∼60 homophilic cell adhesion molecules expressed across three gene clusters (Pcdha, Pcdhb, and Pcdhg) with a variety of essential roles in the developing nervous system. Some of these roles rely on specific isoforms, whereas others are more consistent with a model of isoform redundancy or a
Cathy M. McLeod   +4 more
wiley   +1 more source

Retrograde Melanopsin Signaling Increases With Age in Retinal Degenerate Mice Lacking Rods and the Majority of Cones [PDF]

open access: yes, 2016
PURPOSE: Following on from reports of retrograde retinal signaling in mice, we sought to investigate the influence of age and retinal location on this phenomenon using mice that lack rods and the majority of cones. METHODS: We used functional anatomy for
Coffey, P, Gias, C, Semo, M, Vugler, A
core   +1 more source

Melanopsin Tristability for Sustained and Broadband Phototransduction [PDF]

open access: yesNeuron, 2015
Mammals rely upon three ocular photoreceptors to sense light: rods, cones, and intrinsically photosensitive retinal ganglion cells (ipRGCs). Rods and cones resolve details in the visual scene. Conversely, ipRGCs integrate over time and space, primarily to support "non-image" vision. The integrative mechanisms of ipRGCs are enigmatic, particularly since
Emanuel, Alan Joseph   +1 more
openaire   +2 more sources

Seasonal Variations in Adults with and without Cataracts [PDF]

open access: yes, 2017
Seasonal adaptation is a ubiquitous behavior seen in many species on both global hemispheres and is conveyed by changing photoperiods. In humans this seasonal adaptation is less apparent, in part because changes in daylength are masked by the use of ...
Hashemi, Kattayoon   +4 more
core   +1 more source

Infrared Neural Stimulation Elicits Distinct Molecular Pathways in Astrocytes Based on Laser Pulse Parameters

open access: yesAdvanced Biology, Volume 9, Issue 12, December 2025.
Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams   +7 more
wiley   +1 more source

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