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Melatonin, originally discovered as a hormone of the pineal gland, is produced by bacteria, protozoa, plants, fungi, invertebrates, and various extrapineal sites of vertebrates, including gut, skin, Harderian gland, and leukocytes. Biosynthetic pathways seem to be identical.
Hardeland, Ruediger +2 more
europepmc +5 more sources
The pineal gland is a neuroendocrine organ that plays an important role in anti-inflammation through the hormone melatonin. The anti-inflammatory effects of melatonin and its derivatives have been reported in both in vitro and in vivo models.
Pimpichaya Sangchart +5 more
doaj +1 more source
Plants are a rich source of phytochemical compounds with antioxidant activity. Several studies have revealed that the consumption of plant polyphenols reduces the risk of diseases. Purple corn (Zea mays L.
Juthamat Ratha +8 more
doaj +1 more source
Mung bean (Vigna radiata L.) sprouts are increasingly consumed and have become part of a healthy diet. The sprouts are composed of proteins, carbohydrates, and biochemical compounds.
Pimolwan Siriparu +7 more
doaj +1 more source
Melatonin is the principal hormone secreted by the pineal gland, produced in humans with a circadian rhythm characterized by elevated blood levels during the night. It is involved in the regulation of several rhythmic functions in various vertebrates, and participates in the processing of photoperiodic information.
M. MOR +3 more
+8 more sources
Effect of N-Amide Substitution on Antioxidative Activities of Melatonin Derivatives
Five N-amide substituted melatonin (MLT) derivatives were synthesized and evaluated for antioxidative activities, and compounds 9−12 showed higher electron spin resonance (ESR) response than MLT. 4-Bromobenzoyl and naphthoyl derivatives (10 and 11)
Panyada Panyatip +4 more
doaj +1 more source
The effects of melatonin treatment on oxidative stress induced by ovariohysterectomy in dogs
Background As one of the most common surgeries performed in veterinary medicine, ovariohysterectomy (OHE) can induce oxidative stress in dogs. The antioxidant properties of melatonin have been confirmed in various studies. This study aimed to investigate
Sina Salavati +4 more
doaj +1 more source
Throughout the history of melatonin research, almost exclusive focus has been on nocturnally-generated pineal melatonin production, which accounts for its circadian rhythm in the blood and cerebrospinal fluid; these light/dark melatonin cycles drive the ...
Dun-Xian Tan +3 more
doaj +1 more source
Background Ovariohysterectomy (OHE) induces inflammation and stress in female dogs. The anti‐inflammatory effects of melatonin have been reported in several studies.
Sina Salavati +4 more
doaj +1 more source
As one of the cash crops, cotton is facing the threat of abiotic stress during its growth and development. It has been reported that melatonin is involved in plant defense against salt stress, but whether melatonin can improve cotton salt tolerance and ...
Yuexin Zhang +16 more
doaj +1 more source

