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Melatonin

The International Journal of Biochemistry & Cell Biology, 2006
Melatonin, originally discovered as a hormone of the pineal gland, is produced by bacteria, protozoa, plants, fungi, invertebrates, and various extrapineal sites of vertebrates, including gut, skin, Harderian gland, and leukocytes. Biosynthetic pathways seem to be identical.
Hardeland, Ruediger, Pandi-Perumal, Seithikurippu R., Cardinali, Daniel P.   +2 more
europepmc   +5 more sources

Melatonin mitigates autophagy: unlocking conditional resilience in sheep trophoblast cells exposed to a hypoxic environment [PDF]

Reproduction and Fertility
Melatonin is a key molecule in supporting pregnancy success in sheep, particularly under suboptimal conditions. In humans, melatonin is also known for its antioxidant properties.
Irene Viola, Paolo Accornero, Elisa Quarati, Isabella Manenti, Silvia Miretti, Francisco Canto, José Alfonso Abecia, Paola Toschi   +7 more
doaj   +2 more sources

Anti-Inflammatory Comparison of Melatonin and Its Bromobenzoylamide Derivatives in Lipopolysaccharide (LPS)-Induced RAW 264.7 Cells and Croton Oil-Induced Mice Ear Edema

Molecules, 2021
The pineal gland is a neuroendocrine organ that plays an important role in anti-inflammation through the hormone melatonin. The anti-inflammatory effects of melatonin and its derivatives have been reported in both in vitro and in vivo models.
Pimpichaya Sangchart, Panyada Panyatip, Teerasak Damrongrungruang, Aroonsri Priprem, Pramote Mahakunakorn, Ploenthip Puthongking   +5 more
doaj   +1 more source

Polyphenol and Tryptophan Contents of Purple Corn (Zea mays L.) Variety KND and Butterfly Pea (Clitoria ternatea) Aqueous Extracts: Insights into Phytochemical Profiles with Antioxidant Activities and PCA Analysis

Plants, 2023
Plants are a rich source of phytochemical compounds with antioxidant activity. Several studies have revealed that the consumption of plant polyphenols reduces the risk of diseases. Purple corn (Zea mays L.
Juthamat Ratha, Chawalit Yongram, Panyada Panyatip, Patcharapol Powijitkul, Pimolwan Siriparu, Suthida Datham, Aroonsri Priprem, Tarapong Srisongkram, Ploenthip Puthongking   +8 more
doaj   +1 more source

Effect of Germination and Illumination on Melatonin and Its Metabolites, Phenolic Content, and Antioxidant Activity in Mung Bean Sprouts

Plants, 2022
Mung bean (Vigna radiata L.) sprouts are increasingly consumed and have become part of a healthy diet. The sprouts are composed of proteins, carbohydrates, and biochemical compounds.
Pimolwan Siriparu, Panyada Panyatip, Thanawat Pota, Juthamat Ratha, Chawalit Yongram, Tarapong Srisongkram, Bunleu Sungthong, Ploenthip Puthongking   +7 more
doaj   +1 more source

Melatonin

Current Medicinal Chemistry, 1999
Melatonin is the principal hormone secreted by the pineal gland, produced in humans with a circadian rhythm characterized by elevated blood levels during the night. It is involved in the regulation of several rhythmic functions in various vertebrates, and participates in the processing of photoperiodic information.
M. MOR, P. V. PLAZZI, SPADONI, GILBERTO, TARZIA, GIORGIO   +3 more
  +8 more sources

Effect of N-Amide Substitution on Antioxidative Activities of Melatonin Derivatives

Scientia Pharmaceutica, 2020
Five N-amide substituted melatonin (MLT) derivatives were synthesized and evaluated for antioxidative activities, and compounds 9−12 showed higher electron spin resonance (ESR) response than MLT. 4-Bromobenzoyl and naphthoyl derivatives (10 and 11)
Panyada Panyatip, Nutjaree Pratheepawanit Johns, Aroonsri Priprem, Kouichi Nakagawa, Ploenthip Puthongking   +4 more
doaj   +1 more source

The effects of melatonin treatment on oxidative stress induced by ovariohysterectomy in dogs

BMC Veterinary Research, 2021
Background As one of the most common surgeries performed in veterinary medicine, ovariohysterectomy (OHE) can induce oxidative stress in dogs. The antioxidant properties of melatonin have been confirmed in various studies. This study aimed to investigate
Sina Salavati, Asghar Mogheiseh, Saeed Nazifi, Atefeh Amiri, Behrooz Nikahval   +4 more
doaj   +1 more source

Melatonin attenuates oxidative stress and modulates inflammatory response after experimental burn trauma [PDF]

, 2018
Introduction. Thermal injury activates an inflammatory response. Melatonin possesses anti-oxidant and anti-inflammatory properties. The objective of the present work was to study melatonin effects on the inflammatory response under ...
Atanasova, Milena, Bekyarova, Ganka, Hristova, Minka, Tzaneva, Maria   +3 more
core   +6 more sources

Melatonin combined with endoplasmic reticulum stress induces cell death via the PI3K/Akt/mTOR pathway in B16F10 melanoma cells. [PDF]

PLoS ONE, 2014
This study investigated B16F10 melanoma cell death induced by melatonin combined with endoplasmic reticulum (ER) stress through the PI3K/Akt/mTOR pathway.
Han Sung Kim, Tack-Joong Kim, Yeong-Min Yoo   +2 more
doaj   +1 more source