Results 91 to 100 of about 181,700 (339)

Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function

European Journal of Heart Failure, EarlyView.
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard, Mahmoud Abdellatif, Ioanna Andreadou, Christian Bär, Luc Bertrand, Bianca J.J.M. Brundel, Gemma Chiva‐Blanch, Sean M. Davidson, Dana Dawson, Fabio Di Lisa, Paul Evans, Zoltan Giricz, Derek J. Hausenloy, Petra Kleinbongard, Frank Lezoualc'h, Elisa Liehn, Christoph Maack, Ange Maguy, Elizabeth Murphy, Cinzia Perrino, Maurizio Pesce, Peter P. Rainer, Katrin Streckfuss‐Bömeke, Matthias Thielmann, Rong Tian, Carlo G. Tocchetti, Jolanda Van Der Velden, Sophie Van Linthout, Serena Zacchigna, Thomas Krieg   +29 more
wiley   +1 more source

Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]

, 2016
Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E., Calandra, Ricardo Saul, Micevych, P. E., Paredes, A. H., Rudolph, L. M., Tesone, Marta, Wu, T. J.   +6 more
core   +1 more source

Ambient technology in epilepsy clinical practice

Epilepsia Open, EarlyView.
Abstract The utilization of large language model‐based artificial intelligence (AI) in the field of neurology has gained attention as a viable tool to enhance and assist providers with processes ranging from scheduling patients to providing preliminary interpretations of testing results, pending orders, and documenting encounters. Epileptologists could
Haania Kakwan, Justin F. Rousseau, Lidia M. Moura, Irfan S. Sheikh   +3 more
wiley   +1 more source

Melatonin decreases excessive polyspermy for single oocyte in pigs through the MT2 receptor

Scientific Reports
Melatonin supplementation during in vitro maturation (IVM) improves porcine oocyte maturation and embryonic development by exerting antioxidative effects.
Jing-Tao Sun, Jia-Hui Liu, Lu Zhao, Hang-Yu Chen, Ren-Fei Wang, Yong-Jia Li, Xiao-Gang Weng, Zhong-Hua Liu, Qian Shen, Bao-Xiu Zhang, Jun-Xue Jin   +10 more
doaj   +1 more source

Melatonin as an anti-stress signal: effects on an acute stress model and direct actions on interrenal tissue in goldfish

Frontiers in Endocrinology
BackgroundMelatonin is a key hormone in regulation of circadian rhythms, and involved in many rhythmic functions, such as feeding and locomotor activity. Melatonin reportedly counteracts stress responses in many vertebrates, including fish.
Clara Azpeleta, Clara Azpeleta, Mª Jesús Delgado, Juriaan R. Metz, Gert Flik, Nuria de Pedro   +5 more
doaj   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Melatonin: Clinical Perspectives in Neurodegeneration

Frontiers in Endocrinology, 2019
Prevention of neurodegenerative diseases is presently a major goal for our Society and melatonin, an unusual phylogenetically conserved molecule present in all aerobic organisms, merits consideration in this respect.
Daniel P. Cardinali
doaj   +1 more source

Circadian clocks and breast cancer [PDF]

, 2016
Circadian clocks respond to environmental time cues to coordinate 24-hour oscillations in almost every tissue of the body. In the breast, circadian clocks regulate the rhythmic expression of numerous genes.
Blakeman, V, Meng, Q-J, Streuli, CH, Williams, JL   +3 more
core   +2 more sources

Food for Thought: A Systematic Review and Meta‐Analysis on the Effects of Ultra‐Processed Foods on Cognition in Children and Adolescents

Food Frontiers, EarlyView.
Across 35 studies, this systematic review and meta‐analysis explored the link between ultra‐processed foods (UPFs) and cognition. For children, higher consumption of UPFs was associated with poorer attention, executive functioning, fluid intelligence, and language; for adolescents, higher UPF consumption was associated with poorer executive functioning,
Lan Nguyen, Jared Walters, Bernadette Spies, Amelia Coppus, Jenaya Massie, Thamiris Penteado Bertonha   +5 more
wiley   +1 more source

Melatonin reduces intramuscular fat deposition by promoting lipolysis and increasing mitochondrial function

Journal of Lipid Research, 2019
In obesity and diabetes, intramuscular fat (IMF) content correlates markedly with insulin sensitivity, which makes IMF manipulation an area of therapeutic interest.
Kaiqing Liu, Wensai Yu, Wei Wei, Xinbao Zhang, Ye Tian, Melak Sherif, Xin Liu, Chao Dong, Wangjun Wu, Lifan Zhang, Jie Chen   +10 more
doaj