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Melatonin interacts in multiple ways with microglia, both directly and, via routes of crosstalk with astrocytes and neurons, indirectly. These effects of melatonin are of relevance in terms of antioxidative protection, not only concerning free-radical detoxification, but also in prevention of processes that cause, promote, or propagate oxidative stress
Hardeland, Rüdiger+1 more
openaire +3 more sources
Melatonin and Melatonin-Rich Foods
Vegetables and fruits are found in the most popular diets. And they are considered as rich sources of vitamins and minerals. Vitamin and mineral deficiency are one of the major causes of various diseases that are common nowadays. Especially vitamins which are known to affect directly on various hormones in our body.
İhsan ŞAT, Halil İbrahim BİNİCİ
openaire +4 more sources
Melatonin is the principal hormone secreted by the pineal gland, produced in humans with a circadian rhythm characterized by elevated blood levels during the night. It is involved in the regulation of several rhythmic functions in various vertebrates, and participates in the processing of photoperiodic information.
MOR, Marco+3 more
+8 more sources
In the present study, we created the weight gain models with Min and Yorkshire pigs and conducted the metagenomics and metabolomics of colon contents and transcriptomics of colon tissue. Further, we revealed the characteristics and functions of the colonic microbiota in Min and Yorkshire pigs and analyzed their interactions with the host. Overall, this
Xiaoyu Huang+6 more
wiley +1 more source
Throughout the history of melatonin research, almost exclusive focus has been on nocturnally-generated pineal melatonin production, which accounts for its circadian rhythm in the blood and cerebrospinal fluid; these light/dark melatonin cycles drive the ...
Dun-Xian Tan+3 more
doaj +1 more source
To what extent does photoperiod affect cattle reproduction? Clinical perspectives of melatonin administration [PDF]
The seasonality of reproduction in most mammals is dictated by photoperiod, temperature and nutrition. Melatonin, mainly synthesized in the pineal gland, is generally accepted as the active mediator of photoperiod responses including reproduction.
De Rensis, F.+3 more
core +1 more source
Melatonin Alters Age-Related Changes in Transcription Factors and Kinase Activation [PDF]
Male mice were fed 40 ppm melatonin for 2 months prior to sacrifice at age 26 months, and compared with both 26 and 4 month-old untreated controls. The nuclear translocation of NF-κB increased with age in both brain and spleen and this was reversed by ...
A Jagota+35 more
core +4 more sources
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various preclinical epilepsy research disciplines.
Laura Bindila+11 more
wiley +1 more source
From implantation to birth: insight into molecular melatonin functions [PDF]
Melatonin is a lipophilic hormone synthesized and secreted mainly in the pineal gland, acting as a neuroendocrine transducer of photoperiodic information during the night.
Carlomagno, Gianfranco+3 more
core +1 more source
Melatonin modulates inflammatory response and suppresses burn-induced apoptotic injury [PDF]
Introduction: Melatonin, the principal secretory product of the pineal gland, has antioxidant functions as a potent antioxidant and free radical scavenger.
Atanasova, Milena+3 more
core +6 more sources