Results 21 to 30 of about 181,700 (339)
Melatonin synthesis in the human pineal gland [PDF]
Poster presentation: The mammalian pineal organ is a peripheral oscillator, depending on afferent information from the so-called master clock in the suprachiasmatic nuclei of the hypothalamus.
Ackermann, Katrin+4 more
core +1 more source
In vitro cytoprotective and in vivo anti-oral mucositis effects of melatonin and its derivatives [PDF]
According to our preliminary study, melatonin and its N-amide derivatives (N-(2-(1-4-bromobenzoyl-5-methoxy-1H-indol-3-yl)ethyl)acetamide (BBM) and 4-bromo-N-(2-(5-methoxy-1H-indol-3-yl)ethyl)benzamide (EBM)) inhibited the marker of acute inflammation in
Pramote Mahakunakorn+6 more
doaj +2 more sources
Ovarian cancer (OC) is the most lethal gynecologic malignancy, and melatonin has shown various antitumor properties. Herein, we investigated the influence of melatonin therapy on energy metabolism and mitochondrial integrity in SKOV-3 cells and tested ...
Maira Smaniotto Cucielo+8 more
doaj +1 more source
Urban-like night illumination reduces melatonin release in European blackbirds (Turdus merula): implications of city life for biological time-keeping of songbirds [PDF]
<p>Introduction: Artificial light-at-night is known to affect a broad array of behaviours and physiological processes. In urbanized bird species, light-at-night advances important biological rhythms such as daily cycles of activity/rest and timing
Dominoni, D.M.+3 more
core +2 more sources
Melatonin, originally discovered as a hormone of the pineal gland, is produced by bacteria, protozoa, plants, fungi, invertebrates, and various extrapineal sites of vertebrates, including gut, skin, Harderian gland, and leukocytes. Biosynthetic pathways seem to be identical.
Hardeland, Ruediger+2 more
openaire +3 more sources
Background Melatonin is considered to be a polyfunctional master regulator in animals and higher plants. Exogenous melatonin inhibits plant infection by multiple diseases; however, the role of melatonin in Cucumber green mottle mosaic virus (CGMMV ...
Ling-Ling Yang+10 more
doaj +1 more source
Cytoprotective effects of melatonin against amitriptyline-induced toxicity in isolated rat hepatocytes [PDF]
Purpose: Amitriptyline, one of the commonly used tricyclic antidepressants, caused rare but severe hepatotoxicity in patients who received it continuously. Previous findings showed that the intermediate metabolites of amitriptyline produced by CYP450 are
Dastmalchi, S.+3 more
core +1 more source
Melatonin is a new kind of plant growth regulator. The aim of this study was to figure out the effect of melatonin on arbuscular mycorrhizal (AM) symbiosis and heavy metal tolerance.
Xiangyu Zhang+4 more
doaj +1 more source
Melatonin for rapid eye movement sleep behavior disorder in Parkinson's disease : a randomised controlled trial [PDF]
Background Melatonin may reduce REM-sleep behavior disorder (RBD) symptoms in Parkinson's disease (PD), though robust clinical trials are lacking. Objective To assess the efficacy of prolonged-release (PR) melatonin for RBD in PD.
Coeytaux Jackson, Alessandra+10 more
core +1 more source
Effects of Duodenal 5-Hydroxytryptophan Perfusion on Melatonin Synthesis in GI Tract of Sheep
The purpose of this study is to investigate the potential effects of 5-hydroxytryptophan (5-HTP) duodenal perfusion on melatonin (MT) synthesis in the gastrointestinal (GI) tract of sheep.
Jun Pan+9 more
doaj +1 more source