Results 31 to 40 of about 118,918 (292)

Melatonin metabolism, signaling, and possible roles in plants.

The Plant Journal, 2020
Melatonin is a multifunctional biomolecule found in both animals and plants. In this review, the biosynthesis, levels, signaling, and possible roles of melatonin and its metabolites in plants is summarized. Tryptamine 5-hydroxylase (T5H), which catalyzes
K. Back
semanticscholar   +1 more source

Melatonin distribution reveals clues to its biological significance in basal metazoans.

PLoS ONE, 2012
Although nearly ubiquitous in nature, the precise biological significance of endogenous melatonin is poorly understood in phylogenetically basal taxa.
Modi Roopin, Oren Levy
doaj   +1 more source

Melatonin suppresses sympathetic vasomotor tone through enhancing GABAA receptor activity in the hypothalamus

Frontiers in Physiology, 2023
Introduction: Melatonin (5-methoxy-N-acetyl-tryptamine) is a circadian hormone synthesized and secreted by the pineal gland. In addition to regulating circadian rhythms of many physiological functions, melatonin is involved in regulating autonomic ...
Qiyao Yu, Qiyao Yu, Qi Guo, Qi Guo, Sheng Jin, Chao Gao, Peiru Zheng, De-Pei Li, Yuming Wu, Yuming Wu   +9 more
doaj   +1 more source

Melatonin Reverses the Warburg-Type Metabolism and Reduces Mitochondrial Membrane Potential of Ovarian Cancer Cells Independent of MT1 Receptor Activation

Molecules, 2022
Ovarian cancer (OC) is the most lethal gynecologic malignancy, and melatonin has shown various antitumor properties. Herein, we investigated the influence of melatonin therapy on energy metabolism and mitochondrial integrity in SKOV-3 cells and tested ...
Maira Smaniotto Cucielo, Roberta Carvalho Cesário, Henrique Spaulonci Silveira, Letícia Barbosa Gaiotte, Sérgio Alexandre Alcantara dos Santos, Debora Aparecida Pires de Campos Zuccari, Fábio Rodrigues Ferreira Seiva, Russel J. Reiter, Luiz Gustavo de Almeida Chuffa   +8 more
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Melatonin: Pharmacology, Functions and Therapeutic Benefits

Current Neuropharmacology, 2017
: Background: Melatonin synchronizes central but also peripheral oscillators (fetal adrenal gland, pancreas, liver, kidney, heart, lung, fat, gut, etc.), allowing temporal organization of biological functions through circadian rhythms (24-hour cycles) in
S. Tordjman, S. Chokron, R. Delorme, Annaëlle Charrier, É. Bellissant, N. Jaafari, C. Fougerou   +6 more
semanticscholar   +1 more source

Effects of long-term light, darkness and oral administration of melatonin on serum levels of melatonin

Biomedical Journal, 2016
Background: Continuous light or darkness has various effects on different systems. In the present research work, the effects of constant light and darkness exposure of male rats and oral administration of exogenous melatonin on the serum levels of ...
Naser Farhadi, Majid Gharghani, Zahra Farhadi   +2 more
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Melatonin regulates gene expressions through activating auxin synthesis and signaling pathways

Frontiers in Plant Science, 2022
BackgroundBoth melatonin and indole-3-acetic acid (IAA) are derived from tryptophan. And the most interesting and unsolved puzzle in melatonin research is that what is the relationship between melatonin and auxin?MethodsIn this study, we performed ...
Wei Wei, Jian-Jun Tao, Cui-Cui Yin, Shou-Yi Chen, Jin-Song Zhang, Jin-Song Zhang, Wan-Ke Zhang   +6 more
doaj   +1 more source

Analysis of melatonin content and gene expression in Chinese cherry leaves [PDF]

E3S Web of Conferences, 2020
To investigate the accumulation characteristics and mechanism of melatonin in cherry leaves of different leaf ages, the melatonin content and the expression of synthetic genes in cherry leaves of different leaf ages were measured. The results showed that
Wang Xin, Shen Tian, Zhang Xuefeng, Hu Peng, Tu Hongxia, Zhou Gui-hong, Liang Dong, Xia Hui   +7 more
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Melatonin Mitigates Chilling-Induced Oxidative Stress and Photosynthesis Inhibition in Tomato Plants

Antioxidants, 2020
Melatonin has been demonstrated to play a variety of roles in plants. Of particular importance is its role as a potent antioxidative agent. In the present study, we generated melatonin-deficient tomato plants using virus-induced gene silencing (VIGS ...
Meiling Wang, Shuoxin Zhang, Fei Ding
doaj   +1 more source

Molecular Regulation of Antioxidant Melatonin Biosynthesis by Brassinosteroid Acting as an Endogenous Elicitor of Melatonin Induction in Rice Seedlings

Antioxidants, 2022
Gibberellic acid (GA) was recently shown to induce melatonin synthesis in rice. Here, we examined whether brassinosteroids (BRs) also induce melatonin synthesis because BRs and GA show redundancy in many functions. Among several plant hormones, exogenous
Ok Jin Hwang, Kyoungwhan Back
doaj   +1 more source