Results 31 to 40 of about 181,700 (339)
Melatonin distribution reveals clues to its biological significance in basal metazoans.
PLoS ONE, 2012 Although nearly ubiquitous in nature, the precise biological significance of endogenous melatonin is poorly understood in phylogenetically basal taxa.
Modi Roopin, Oren Levy
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Frontiers in Physiology, 2023 Introduction: Melatonin (5-methoxy-N-acetyl-tryptamine) is a circadian hormone synthesized and secreted by the pineal gland. In addition to regulating circadian rhythms of many physiological functions, melatonin is involved in regulating autonomic ...
Qiyao Yu +9 more
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Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety [PDF]
, 2010 <p>Background: Melatonin is extensively used in the USA in a non-regulated manner for sleep disorders. Prolonged release melatonin (PRM) is licensed in Europe and other countries for the short term treatment of primary insomnia in patients aged 55 ...
A Brzezinski +52 more
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Analysis of melatonin content and gene expression in Chinese cherry leaves [PDF]
E3S Web of Conferences, 2020 To investigate the accumulation characteristics and mechanism of melatonin in cherry leaves of different leaf ages, the melatonin content and the expression of synthetic genes in cherry leaves of different leaf ages were measured. The results showed that
Wang Xin +7 more
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Biomedical Journal, 2016 Background: Continuous light or darkness has various effects on different systems. In the present research work, the effects of constant light and darkness exposure of male rats and oral administration of exogenous melatonin on the serum levels of ...
Naser Farhadi +2 more
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Abnormal hippocampal melatoninergic system: a potential link between absence epilepsy and depression-like behavior in WAG/Rij rats? [PDF]
, 2018 Absence epilepsy and depression are comorbid disorders, but the molecular link between the two disorders is unknown. Here, we examined the role of the melatoninergic system in the pathophysiology of spike and wave discharges (SWDs) and depression-like ...
Battaglia, Giuseppe +8 more
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The role of melatonin in the development of postmenopausal osteoporosis
Frontiers in Pharmacology, 2022 Melatonin is an important endogenous hormone that modulates homeostasis in the microenvironment. Recent studies have indicated that serum melatonin levels are closely associated with the occurrence and development of osteoporosis in postmenopausal women.
Keda Yang +3 more
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Salivary melatonin onset in youth at familial risk for bipolar disorder [PDF]
, 2019 Melatonin secretion and polysomnography (PSG) were compared among a group of healthy adolescents who were at high familial risk for bipolar disorder (HR) and a second group at low familial risk (LR).
Armitage, Roseanne +13 more
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Nutrition Reviews, 2009 Once thought to be exclusively a molecule of the animal kingdom, melatonin has now been found to exist in plants as well. Among a number of actions, melatonin is a direct free radical scavenger and an indirect antioxidant. Melatonin directly detoxifies the hydroxyl radical (OH), hydrogen peroxide, nitric oxide, peroxynitrite anion, peroxynitrous acid ...
Russel J. Reiter +3 more
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Melatonin regulates gene expressions through activating auxin synthesis and signaling pathways
Frontiers in Plant Science, 2022 BackgroundBoth melatonin and indole-3-acetic acid (IAA) are derived from tryptophan. And the most interesting and unsolved puzzle in melatonin research is that what is the relationship between melatonin and auxin?MethodsIn this study, we performed ...
Wei Wei +6 more
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