Results 11 to 20 of about 335 (142)
New data on well-known drug: focus on meldonium
Медицинский совет, 2021 The article reviews the efficacy of meldonium in patients with various diseases, which are based on secondary mitochondrial dysfunction. Mitochondria are complex cellular organelles that control many metabolic processes, including fatty acid oxidation ...
M. E. Statsenko +2 more
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Meldonium – A High Potential Drug. Literature Review
Quality in SportIntroduction and purpose: Meldonium is a long-established substance. Initially, the substance was only available in the former Soviet Union; now the drug can be obtained, for example, in Poland.
Michał Ochwat +7 more
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Meldonium and neuroprotection. Theory, experiment and clinical practice.
Medičnì Perspektivi, 2018 In this review the possibilities of correction of brain metabolism in cases of acute cerebral ischemia (ACI) under using meldonium were considered. The biochemical specificity of this remedy in Krebs cycle, influence on cerebral glycolysis, by activating
V. P. Muslin, O. V. Pohorielov
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MELDONIUM EFFICACY IN CHRONIC CEREBROVASCULAR DISEASES
Медицинский совет, 2016 The evidential base of meldonium in chronic cerebral ischemia is critically reviewed in the article.
M. A. DOMASHENKO, M. Yu. MAKSIMOVA
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MELDONIUM: EFFECTIVE ACTION POINTS
Кардиоваскулярная терапия и профилактика, 2013 The paper is focused on hypoxia and cell ischemia as universal pathogenetic mechanisms of disease development, which can be addressed by both etiotropic and pathogenetic therapy. The latter is represented by the so-called metabolic correctors. At present,
A. L. Vertkin +4 more
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Meldonium Supplementation in Professional Athletes: Career Destroyer or Lifesaver? [PDF]
CureusMeldonium is a substance with known anti-anginal effects demonstrated by numerous studies and human clinical trials; however, it does not possess marketing authorization within the European Union, only in ex-Soviet republics. Since 2016, meldonium has been included by the World Anti-doping Agency (WADA) on the S4 list of metabolic modulators.
Pușcaș A +8 more
europepmc +3 more sources
EFFICACY OF MELDONIUM IN ACUTE PERIOD OF ISCHEMIC STROKE
Alʹmanah Kliničeskoj Mediciny, 2016 Background: As long as systemic thrombolysis is indicated to not more than 10% of patients with ischemic stroke, the search for medical agents for basic treatment of stroke is an important problem of today’s neurology.Aim: To evaluate efficacy of ...
S. V. Kotov +4 more
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METABOLIC CARDIOPROTECTION: NEW CONCEPTS IN IMPLEMENTATION OF CARDIOPROTECTIVE EFFECTS OF MELDONIUM [PDF]
Research Results in Pharmacology, 2016 Recent studies confirm the need to find means to correct ischemic / reperfusion injury due to the hemodynamic medicine, which are already known do not have the proper cardioprotective effects.
Lyudmila Danilenko +3 more
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Left ventricular noncompaction cardiomyopathy and short QT syndrome due to primary carnitine deficiency. [PDF]
Ann Noninvasive Electrocardiol, 2023 A 13‐year‐old patient with palpitations and syncope was diagnosed with a rare, reversible cause of short QT syndrome (SQTS) and cardiomyopathy—primary carnitine deficiency (PCD) caused by a mutation in the SLC22A5 gene. Treatment with carnitine supplementation corrected her QT interval to within normal range, with significant improvement in ventricular
Hanington OP +4 more
europepmc +2 more sources
β-Hydroxy β-Methyl Butyric Acid (HMB) and Its Potential Doping Relevance: A Pilot Study on Its Urinary Excretion Profile. [PDF]
Drug Test Analβ‐hydroxy β‐methyl butyric acid (HMB), either as the free acid or in the form of its calcium salt, is a component of several dietary supplements marketed to enhance sports performance. We investigated the urinary excretion profile of HMB, also assessing the endogenous reference ranges of HMB in human urine samples from healthy volunteers (n = 20). Data
Camuto C +3 more
europepmc +2 more sources