Results 21 to 30 of about 335 (142)

An Unusual Oxidative Rearrangement Catalyzed by a Divergent Member of the 2‐Oxoglutarate‐Dependent Dioxygenase Superfamily during Biosynthesis of Dehydrofosmidomycin

open access: yesAngewandte Chemie, Volume 134, Issue 30, July 25, 2022., 2022
DfmD is a highly divergent member of the 2‐oxoglutarate‐dependent dioxygenase superfamily that catalyzes desaturation, rearrangement and demethylation of its substrate. In vitro biochemical studies and homology modeling suggest that these transformations occur via novel chemistry.
Elizabeth I. Parkinson   +5 more
wiley   +2 more sources

New treatment options for a patient with chronic heart failure and chronic obstructive pulmonary disease

open access: yesМедицинский совет, 2022
Introduction. The number of  patients with chronic heart failure  (CHF) and chronic obstructive pulmonary disease  (COPD) is increasing every year. In both CHF and COPD, secondary mitochondrial dysfunction is observed.
M. E. Statsenko   +3 more
doaj   +1 more source

Meldonium: Pharmacological, toxicological, and analytical aspects [PDF]

open access: yesToxicology Research and Application, 2020
Meldonium is the active molecule from Mildronate® with similar chemical structure to an amino acid, and it is known as (3-(2,2,2-trimethylhydrazine) propionate) (CAS 76144-81-5). This pharmaceutical substance is approved in Eastern Europe for cerebral and myocardial ischemia and has been on the World Doping Association’s banned substances list since ...
Dener Gomes Berlato   +1 more
openaire   +1 more source

Dried blood spots for doping controls—Development of a comprehensive initial testing procedure with fully automated sample preparation

open access: yesBiomedical Chromatography, Volume 37, Issue 8, August 2023., 2023
Abstract Currently, primarily urine, whole blood and serum samples are analyzed for doping‐relevant substances in professional sports, but recently dried blood spots (DBS) have been introduced as complementary matrix, offering advantageous features, e.g. a minimally invasive sampling procedure.
Ann‐Marie Garzinsky   +5 more
wiley   +1 more source

COVID-19: the place of metabolic correctors in the therapy of patients with post-COVID syndrome

open access: yesЛечащий Врач, 2022
The frequency of post-COVID syndrome in patients treated on an outpatient basis ranges from 10% to 35%, while in patients who have had a severe disease requiring hospitalization, the frequency of post-COVID syndrome can reach 80%.
G. A. Baryshnikova   +4 more
doaj   +1 more source

Analysis of doping control samples using supercritical fluid chromatography‐tandem mass spectrometry: Ready for routine use

open access: yesJournal of Separation Science, Volume 46, Issue 7, April 2023., 2023
Supercritical fluid chromatography is proving to be a good separation and sample preparation tool for various analytical applications and, as such, has gained the attention of the anti‐doping community. Here, the applicability of supercritical fluid chromatography hyphenated to tandem mass spectrometry for routine doping control analysis was tested.
Bernhard Wuest   +5 more
wiley   +1 more source

Annual banned‐substance review—Analytical approaches in human sports drug testing 2021/2022–

open access: yesDrug Testing and Analysis, Volume 15, Issue 1, Page 5-26, January 2023., 2023
Detection assays for drugs and methods of sports doping published between 2021 and 2022 are critically reviewed and evaluated in context with the Prohibited List 2022 as established by the World Anti‐Doping Agency. Abstract Also in 2021/2022, considerable efforts were invested into advancing human sports drug testing programs, recognizing and taking ...
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

New opportunities in the treatment of asthenic symptoms after a new coronavirus infection

open access: yesМедицинский совет, 2022
Introduction. Asthenia is an urgent problem during the pandemic of new coronavirus infection (COVID-19) because of its high frequency regardless of the severity of the disease.The purpose of this subanalysis of data from the multicenter controlled ...
V. N. Shishkova, A. I. Martynov
doaj   +1 more source

Unassisted Switchable Dual-Photoelectrode Devices Utilizing p-n Carbon Quantum Dots as "Semiconductor Electrolytes": Optimization Between H<sub>2</sub>O<sub>2</sub> and Solar Electricity Production. [PDF]

open access: yesAdv Sci (Weinh)
p‐n type carbon quantum dots (N‐CQDs) are designed as a conceptually‐new “semiconductor electrolyte” to develop a self‐driven photoelectrochemical cell that can be switched to optimize between H2O2 production and electricity generation under visible‐light illumination with water and O2 as reaction reagents.
Duan HM   +8 more
europepmc   +2 more sources

Annual banned‐substance review: Analytical approaches in human sports drug testing 2020/2021

open access: yesDrug Testing and Analysis, Volume 14, Issue 1, Page 7-30, January 2022., 2022
Detection assays for drugs and methods of sports doping published between 2020 and 2021 are critically reviewed and evaluated in context with the Prohibited List 2021 as established by the World Anti‐Doping Agency. Abstract Most core areas of anti‐doping research exploit and rely on analytical chemistry, applied to studies aiming at further improving ...
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

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