Results 41 to 50 of about 335 (142)

Metformin Lowers Plasma Triacylglycerol Levels in Mice with Impaired Carnitine Biosynthesis and Fatty Liver

open access: yesSynBio
The antidiabetic drug metformin has a wide range of metabolic effects and may also reduce the risk of obesity-related diseases. The aim of the current study was to investigate if metformin could counteract meldonium-induced fatty liver.
Bodil Bjørndal   +4 more
doaj   +1 more source

Meldonium use by athletes at the Baku 2015 European Games [PDF]

open access: yesBritish Journal of Sports Medicine, 2016
BackgroundThe aim of this report was to estimate the prevalence of meldonium use in athletes competing in the Baku 2015 European Games to contribute to the surveillance of substances on the 2015 World Anti-Doping Agency (WADA) Monitoring Program. Meldonium is reported to be used by athletes to potentially enhance personal performance and shorten the ...
Mark, Stuart   +2 more
openaire   +2 more sources

Misuse of the metabolic modulator meldonium in sports

open access: yesJournal of Sport and Health Science, 2017
Meldonium is currently claimed to be a relatively safe agent in patients needing anti-ischaemic therapy, but there is no compelling evidence that it may be effective in improving athletic performance, nor that its administration may be safe in healthy subjects.
LIPPI, Giuseppe, MATTIUZZI, Camilla
openaire   +4 more sources

Fluorescence chemosensing of meldonium using a cross-reactive sensor array

open access: yesThe Analyst, 2020
Differential sensing of meldonium was achieved using fluorescent chemosensors.
Ergin Yalcin   +3 more
openaire   +4 more sources

Concepts for a New Rapid and Simple HPLC Method for Simultaneous Determination of Metoprolol and Meldonium in Pharmaceutical Dosage Forms

open access: yesScientia Pharmaceutica, 2022
Simultaneous determination of the tandem of drugs, like meldonium and metoprolol, with enormous polarity differences between them, requires thorough research and careful selection of chromatographic conditions.
Marjan Piponski   +8 more
doaj   +1 more source

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

open access: yesDrug Testing and Analysis, Volume 17, Issue 8, Page 1417-1442, August 2025.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis   +2 more
wiley   +1 more source

Meldonium: drug which brought disrepute to sport

open access: yesInternational Journal of Basic & Clinical Pharmacology, 2017
World of sports have been rocked by doping scandals every now and then and World Anti-Doping Agency(WADA) has banned several offending drugs at different times to counter this menace. Meldonium is the recent addition to the long list of drugs banned by WADA to prevent its misuse among the athletes.
Bikash Ranjan Meher   +2 more
openaire   +2 more sources

Crystallographic and Selectivity Studies on the Approved HIF Prolyl Hydroxylase Inhibitors Desidustat and Enarodustat

open access: yesChemMedChem, Volume 19, Issue 24, December 16, 2024.
Inhibitors of the 2‐oxoglutarate (2OG)‐dependent hypoxia‐inducible factor prolyl hydroxylases (PHDs) are used for anemia treatment. Structures of the clinical PHD inhibitors Desidustat and Enarodustat complexed with the 2OG oxygenase factor inhibiting hypoxia‐inducible factor‐α (FIH) provide a basis to guide future PHD/2OG oxygenase inhibitor ...
Thomas P. Corner   +9 more
wiley   +1 more source

ANTI-ISCHEMIC AND ANTIOXIDANT ACTIVITY OF MELDONIUM IN IHD PATIENTS WITH STABLE ANGINA

open access: yesМедицинский совет, 2016
(IHD), stable angina of effort of functional class II (43 persons) – III (39 persons) (53.3±7.5 y.o., men - 71, women - 11), with concomitant arterial hypertension – in 21 patient.
V. P. MIKHIN, P. Y. TYURIKOV
doaj   +1 more source

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