Results 71 to 80 of about 335 (142)

Unsolved problems of cytoprotective therapy in patients with coronary heart disease

Терапевтический архив, 2015
The paper gives data on the proven efficiency of myocardial cytoprotection with the pFOX inhibitors trimetazidine and meldonium for coronary heart disease.
M E Statsenko, S V Turkina, A A Ermolenko   +2 more
doaj  

DETERMINATION OF MELDONIUM, γ-BUTYROBETAINE, AND CARNITINE IN BLOOD PLASMA BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY WITH MASS-SELECTIVE DETECTION

Разработка и регистрация лекарственных средств, 2019
A procedure for simultaneous quantitative determination of meldonium, L-carnitine, and γ-butyrobetaine in blood plasma by high-performance liquid chromatography with mass-selective detection and the isotopically labeled d9L-carnitine as internal standard
P. N. Sorokoumov, E. I. Savelieva, G. V. Karakashev, V. A. Kopeikin, A. S. Radilov   +4 more
doaj  

Use of meldonium in the combination treatment of patients with heart failure in the early post-infarction period

Терапевтический архив, 2014
AIM: To evaluate the impact of 10-14-day intravenous administration of meldonium as part of combination therapy in patients with chronic heart failure in the early post-infarction period on the recovery period, structural and functional parameters, and ...
M E Statsenko, N N Shilina, S V Turkina
doaj  

Mildronate (meldonium): First, do no harm

, 2020
Meldonium (Mildronate) is used as a cardioprotective drug; however, it has not been officially approved anywhere outside the former Soviet Union (SU). The supposed action mechanism is based on the carnitine (Lcarnitine) lowering effect in muscular and cardiac tissues.
openaire   +1 more source

Meldonium Inhibits Cell Motility and Wound-Healing in Trabecular Meshwork Cells and Scleral Fibroblasts: Possible Applications in Glaucoma. [PDF]

Pharmaceuticals (Basel), 2023
Minnelli C, Piva F, Cecati M, Armeni T, Mobbili G, Galeazzi R, Melecchi A, Cristaldi M, Corsaro R, Rusciano D.   +9 more
europepmc   +1 more source

Role of pFox inhibitors in the treatment of patients with acute myocardial ischemia

Терапевтический архив, 2014
AIM: To evaluate the anti-ischemic and anti-anginal efficacy of meldonium (Idrinol) in its short-term use as part of combination therapy in patients with chronic heart failure in the early post-infarction period/MATERIAL AND METHODS: The investigation ...
M E Statsenko, S V Turkina, N N Shilina
doaj  

The Effects of a Meldonium Pre-Treatment on the Course of the LPS-Induced Sepsis in Rats. [PDF]

Int J Mol Sci, 2022
Đurašević S, Ružičić A, Lakić I, Tosti T, Đurović S, Glumac S, Pejić S, Todorović A, Drakulić D, Stanković S, Jasnić N, Đorđević J, Todorović Z.   +12 more
europepmc   +1 more source

Protective Effects of Meldonium in Experimental Models of Cardiovascular Complications with a Potential Application in COVID-19. [PDF]

Int J Mol Sci, 2021
Vilskersts R, Kigitovica D, Korzh S, Videja M, Vilks K, Cirule H, Skride A, Makrecka-Kuka M, Liepinsh E, Dambrova M.   +9 more
europepmc   +1 more source

The unusual pharmacokinetics of meldonium: Implications for doping

Pharmacological Research, 2016
Edgars, Liepinsh, Maija, Dambrova
openaire   +2 more sources

Cardioprotective Activity of Pharmacological Agents Affecting NO Production and Bioavailability in the Early Postnatal Period after Intrauterine Hypoxia in Rats. [PDF]

Biomedicines, 2023
Popazova O, Belenichev I, Bukhtiyarova N, Ryzhenko V, Oksenych V, Kamyshnyi A.   +5 more
europepmc   +1 more source