Results 171 to 180 of about 104,326 (289)

The interactive Factor H-atypical hemolytic uremic syndrome mutation database and website: update and integration of membrane cofactor protein and Factor I mutations with structural models [PDF]

, 2006
Rebecca E. Saunders, Cynthia Abarrategui-Garrido, Véronique Frémeaux‐Bacchi, Elena Goicoechea de Jorge, Timothy H.J. Goodship, Margarita López‐Trascasa, Marina Noris, Isabel María Ponce Castro, Giuseppe Remuzzi, Santiago Rodrı́guez de Córdoba, Pilar Sánchez‐Corral, Christine Skerka, Peter F. Zipfel, Stephen J. Perkins   +13 more
openalex   +1 more source

Copper‐Doped Prussian Blue Nanozymes With Hyaluronic Acid‐Mediated Targeting Alleviate Oxidative Stress and Regulate Cholesterol Handling for Atherosclerosis Therapy

Advanced Science, EarlyView.
CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...
Jianliang Ou, Ruihua Ji, Qinglu Zang, Mingkang Wang, Lingling Zhou, Yingliang Wei, Di Yang, Yue Wu, Hongxu Zhu, Jianrong Wu, Xiaojun Cai, Wenxian Du, Junjie Cheng, An Zeng, Yuehua Li   +14 more
wiley   +1 more source

Membrane cofactor protein (CD46) is a keratinocyte receptor for the M protein of the group A streptococcus.

, 1995
Nobuhiko Okada, M. Kathryn Liszewski, John Atkinson, Michael G. Caparon   +3 more
openalex   +1 more source

From Circuits to Symphonies: A Systems‐Engineering Blueprint for Multimicrobial Synthetic Biology

Advanced Science, EarlyView.
Engineering synthetic microbial consortia requires moving beyond intracellular genetic circuits toward coordinated multicellular design. A modular systems‐engineering framework is presented that integrates communication, temporal coordination, ecological structuring, and predictive modeling to guide application‐dependent consortium design ...
Miguel Fernández‐Niño, Ludger A. Wessjohann, José Manuel Guillamón, Daniela Burgos‐Toro, Silvia Moriano‐Gutiérrez, Giacomo Di Matteo, Zia‐ul Islam, Rinke van van Tatenhove‐Pel, Vanessa Rossetto Marcelino, Rodrigo Ledesma‐Amaro   +9 more
wiley   +1 more source

Metabolic Labeling and Visualization of Isoprenoids Using Alkyne‐Modified DMAPP Analogs in Bacillus subtilis

Angewandte Chemie, EarlyView.
Fluorescence‐based visualization and targeted mass–spectrometric enrichment of membrane‐embedded isoprenoids in Bacillus subtilis via cell‐permeant, alkynylated DMAPP analogs. ABSTRACT Isoprenoids are a chemically and functionally diverse class of metabolites that underlie essential bacterial physiology including respiration and cell envelope ...
Zackary N. Hulsey, Dillon P. McBee, Claudia L. Dolan, Francis M. Rossi, Neil A. Truslow, Allyson R. Taylor, Thomas N. Trybala, Joshua A. Baccile   +7 more
wiley   +2 more sources

Integrative approaches for the structure-based functional understanding of the ethylene response in plants. [PDF]

Plant J
Kersten LS, Eberle RJ, Groth G, Gohlke H.   +3 more
europepmc   +1 more source

SEPARATION OF SELF FROM NON-SELF IN THE COMPLEMENT SYSTEM: A ROLE FOR MEMBRANE COFACTOR PROTEIN AND DECAY ACCELERATING FACTOR

, 1991
John P. Atkinson, T J Oglesby, David J. White, E A Adams, Megan K. Liszewski   +4 more
openalex   +1 more source

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

Advanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu, Yundi Wu, Shuai Zhang, Hongjuan Zhao, Jiping Zheng, Shiyang Shao, Jianqiang Chen, Xilong Wu   +7 more
wiley   +1 more source

Beyond Canonical CO Oxidation: Structural and Evolutionary Insights Into a Non‐Canonical Carbon Monoxide Dehydrogenase

Angewandte Chemie, EarlyView.
Clade B carbon monoxide dehydrogenases (CODHs) remain enigmatic, diverging from canonical CODHs in structure and function. Here, we present the first characterization of Ruminococcus flavefaciens CODH (RfCODH), revealing occluded substrate pathways and attenuated CO oxidation activity.
Maximilian Böhm, Vivek Srinivas, Benjamin Wiseman, Ping Huang, Moritz Senger, Martin Högbom, Henrik Land   +6 more
wiley   +2 more sources

Chemical Proteomics Reveal the Inventory of Pyrroloquinoline Quinone Binding Proteins in Bacteria. [PDF]

J Am Chem Soc
Wang T, Mühlhofer R, Lei E, Ding W, Klein AS, Zeymer C, Sieber SA.   +6 more
europepmc   +1 more source