Results 191 to 200 of about 104,326 (289)

Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome

, 2003
Anna Richards, Elizabeth J. Kemp, M. Kathryn Liszewski, Judith A. Goodship, Anne Katrin Lampe, Ronny Decorte, M. Hamza Müslümanogğlu, Salìh Kavukçu, Guido Filler, Yves Pirson, Leana S. Wen, John P. Atkinson, Timothy H.J. Goodship   +12 more
openalex   +2 more sources

Characterization of a protein cofactor that mediates protein kinase A regulation of the renal brush border membrane Na(+)-H+ exchanger. [PDF]

, 1995
E. J. Weinman, Deborah Steplock, Yibin Wang, Shirish Shenolikar   +3 more
openalex   +1 more source

Unraveling A4GALT Mechanism and Its Modulation With Adamantyl‐Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies

Angewandte Chemie, EarlyView.
A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster, Òscar Vidal‐Gironès, Rowan de Graaf, Ken Kok, Lindsey T. Lelieveld, Jackelien Hoogervorst, Maria J. Ferraz, José Pablo Rivas‐Fernández, Rob F. Lammers, Herman S. Overkleeft, Johannes M. F. G. Aerts, Rolf G. Boot, Carme Rovira, Marta Artola   +13 more
wiley   +2 more sources

Decoding the Factor H-Related Proteins: Gatekeepers of Complement Dysregulation in AMD. [PDF]

Eur J Immunol
Tang J, Zgoda N, Clark SJ.
europepmc   +1 more source

Nanosecond Structure of Radical Pair Intermediates from High-Frequency Quantum Oscillations: Insight into the Q_A^•- to Q_B Electron Transfer Step in Purple Bacterial Photosynthesis. [PDF]

J Phys Chem B
Matsuoka H, Link G, Heinen U, Poluektov OG, Utschig LM, Thurnauer MC, Weber S, Kothe G.   +7 more
europepmc   +1 more source

SLC25A3 exports mitochondrial copper to metalate cytochrome <i>c</i> oxidase and prevent cuproptosis. [PDF]

Proc Natl Acad Sci U S A
Zulkifli M, Farid I, Oldfather LE, Shanbhag VC, Leary SC, Petris MJ, Cobine PA, Gohil VM.   +7 more
europepmc   +1 more source

The Role of Iron in Neuronal Homeostasis: A Double-Edged Sword. [PDF]

Cells
Sgalletta B, Agostini F, Bisaglia M.
europepmc   +1 more source

Small Heat Shock Protein Hsp17.8 Functions as an AKR2A Cofactor in the Targeting of Chloroplast Outer Membrane Proteins in Arabidopsis    

, 2011
Dae Heon Kim, Zheng‐Yi Xu, Yun Jeong Na, Yun-Joo Yoo, Junho Lee, Eun‐Ju Sohn, Inhwan Hwang   +6 more
openalex   +1 more source

A cell-free system for 1,6-hexanediamine synthesis using bulk chemical caprolactam as the feedstock. [PDF]

Synth Syst Biotechnol
Liu R, Li C, Zhang Y, Li G, Deng Y.
europepmc   +1 more source

Conformational Dynamics of Na⁺-Pumping NADH-Quinone Oxidoreductase during Na⁺ Translocation from AlphaFold-Facilitated Markov State Modeling. [PDF]

J Chem Inf Model
Seki T, Ohnuki J, Okazaki KI.
europepmc   +1 more source