Results 251 to 260 of about 177,226 (339)

Differential expression of complement regulatory proteins decay-accelerating factor (CD55), membrane cofactor protein (CD46) and CD59 during human spermatogenesis.

, 1994
K L Simpson, C H Holmes
openalex   +1 more source

Targeting GRP78 and the Proteostasis Network to Break the Therapeutic Ceiling in Neuroendocrine Prostate Cancer

iNew Medicine, EarlyView.
ABSTRACT HSPA5 (also known as GRP78/BiP) is a master regulator of the endoplasmic reticulum (ER) stress response and a key node in the proteostasis network. In neuroendocrine prostate cancer (NEPC), an aggressive, therapy‐refractory lineage that emerges under pressure from androgen receptor (AR) directed therapies, GRP78 is upregulated and co‐opted to ...
Amos Olalekan Akinyemi, Md Rakibul Alam, Mithu Howlader, Mohammad Esfini Farahani, Lixiang Gu, Chun Li, Chripus Ngule, Kevin Fulp, Bolaji Owoyemi, Xinyi Wang, Samuel Nwadialo, Fatemeh Selani, Makumba Esoe, Obaleye Oluwafunminiyi, Zhiguo Li   +14 more
wiley   +1 more source

A Review of Receptor Recognition Mechanisms in Coronaviruses. [PDF]

Viruses
Liu J, Luo W, Li J, Cai B, Lei Z, Lin S, Chen Z, Yue Z, Chen X, Li Y, Luo Z, Zhang Q, Chen X.   +12 more
europepmc   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source

Improving Cofactor Promiscuity of HMG-CoA Reductase from <i>Ruegeria pomeroyi</i> Through Rational Design. [PDF]

Biomolecules
Xue H, Huang Y, Shah AM, Wang X, Hu Y, Zhang L, Zhao ZK.   +6 more
europepmc   +1 more source

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

De novo design and evolution of an artificial metathase for cytoplasmic olefin metathesis. [PDF]

Nat Catal
Zou Z, Kalvet I, Lozhkin B, Morris E, Zhang K, Chen D, Ernst ML, Zhang X, Baker D, Ward TR.   +9 more
europepmc   +1 more source

Frequency and Associated Factors of Clotted and Hemolyzed Samples in South Gonder Hospitals, Ethiopia: A Multicenter Cross‐Sectional Study, 2023

Journal of Clinical Laboratory Analysis, EarlyView.
This study, conducted in South Gonder hospitals in Ethiopia, investigated the prevalence and causes of clotted and hemolyzed blood samples submitted for hematological testing. The findings revealed a high rate of sample quality issues, with significant associations identified between pre‐analytical factors like collection technique and sample integrity.
Birhanemaskal Malkamu, Getaneh Atikilt Yemata, Andargachew Almaw, Ayenew Assefa, Birhanu Getie, Teklehaimanot Kiros, Mulat Erkihun, Shewaneh Damtie, Tegenaw Tiruneh, Berhanu Abebaw Mekonnen, Meron Asmamaw Alemayehu, Abraham Teym, Abathun Temesgen, Gashaw Melkie Bayeh, Almaw Genet Yeshiwas, Rahel Mulatie Anteneh, Melkamu Aderajew Zemene, Tesfaneh Shimels, Chalachew Yenew, Wolde Melese Ayele, Ahmed Fentaw Ahmed, Assefa Andargie Kassa, Tilahun Degu Tsega, Chalachew Abiyu Ayalew, Sintayehu Simie Tsega, Zeamanuel Anteneh Yigzaw, Amare Genetu Ejigu, Wondimnew Desalegn Addis, Getasew Yirdaw, Kalaab Esubalew Sharew, Daniel Adane, Samuel Berihun Dagnew, Gebyaw Arega, Habitamu Mekonen   +33 more
wiley   +1 more source

Patterns of lipid profile and genetic variations in South Asians. [PDF]

Cardiovasc Diabetol Endocrinol Rep
Rahmanian M.
europepmc   +1 more source

Selenium biofortification: integrating one health and sustainability

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Selenium (Se) biofortification in crops has emerged as a promising strategy to address global Se deficiencies and enhance both agricultural productivity and human health. Increasing the Se content of crops through biofortification improves their resilience to abiotic and biotic stresses and boosts their nutritional value.
Silvia Estarriaga‐Navarro, Nieves Goicoechea, Daniel Plano, Carmen Sanmartín   +3 more
wiley   +1 more source