Results 281 to 290 of about 710,495 (352)

Atypical hemolytic uremic syndrome: diagnosis, management, and discontinuation of therapy. [PDF]

Hematology Am Soc Hematol Educ Program
Java A.
europepmc   +1 more source

CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy

VIEW, EarlyView.
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma, Junxin Chen, Yuan Du, Zhihao Cao, Weizhi Ji, Yuyu Niu, Zebin Yang   +6 more
wiley   +1 more source

The SUV39 Family of H3K9 Methyltransferases in Skeletal Muscle Stem Cells

FASEB BioAdvances, EarlyView.
The SUV39 family members are well known for methylating the Lysine 9 of the histone H3 (H3K9) in order to compact the chromatin and contributing to gene repression. We describe their active role in proliferating and differentiating muscle stem cells, how they prevent from inflammation and fibrosis during muscle regeneration and the future avenues ...
Pauline Garcia, Slimane Ait‐Si‐Ali, Fabien Le Grand   +2 more
wiley   +1 more source

Microscopic basis of reaction center modulation in PsbA variants of photosystem II. [PDF]

Proc Natl Acad Sci U S A
Bhattacharjee S, Gordiy I, Sirohiwal A, Pantazis DA.   +3 more
europepmc   +1 more source

Is Deuterium Sequestering by Reactive Carbon Atoms an Important Mechanism to Reduce Deuterium Content in Biological Water?

FASEB BioAdvances, EarlyView.
Deuterium, a heavy isotope of hydrogen, is universal in nature, but it disrupts the mitochondrial ATPase pumps. One mechanism that biological organisms may use to reduce deuterium levels in the mitochondria is to sequester deuterium bound to carbon atoms in a small set of organic molecules that have a unique configuration to support such trapping ...
Stephanie Seneff, Greg Nigh, Anthony M. Kyriakopoulos   +2 more
wiley   +1 more source

Permeabilisation of the Outer Membrane of Escherichia coli for Enhanced Transport of Complex Molecules. [PDF]

Microb Biotechnol
Casas-Rodrigo I, Vornholt T, Castiglione K, Roberts TM, Jeschek M, Ward TR, Panke S.   +6 more
europepmc   +1 more source

Preparing for successful protein crystallization experiments

Acta Crystallographica Section F, EarlyView.
All crystal‐based structural biology methods, including X‐ray crystallography, serial synchrotron and serial femtosecond crystallography, and electron diffraction, require the preparation of biomolecular crystals. This article covers strategies for careful sample preparation in crystallization experiments to increase the chance of success.Crystal‐based
Gabrielle R. Budziszewski, Vivian Stojanoff, Sarah E. J. Bowman   +2 more
wiley   +1 more source

De novo biosynthesis of nylon 12 monomer ω-aminododecanoic acid. [PDF]

Nat Commun
Ge J, Wang T, Yu H, Ye L.
europepmc   +1 more source

Analysis of the Functional Role of TIMM29 in the Hepatitis B Virus Life Cycle

Microbiology and Immunology, Volume 69, Issue 4, Page 229-246, April 2025.
ABSTRACT Hepatitis B virus (HBV) causes chronic hepatitis B, which can progress to liver cirrhosis and hepatocellular carcinoma. HBV has complex interactions with various cell organelles and proteins that ensure effective progeny virus production. We previously reported that a mitochondrial protein, TIMM29, should regulate the HBV life cycle through ...
Limia Abueldahab, Yadarat Suwanmanee, Nelly Muriungi, Eriko Ohsaki, Masami Wada, Shihoko Kimura‐Ohba, Keiji Ueda   +6 more
wiley   +1 more source

The role of AdhE mutations in <i>Thermoanaerobacterium saccharolyticum</i>. [PDF]

J Bacteriol
Fabri JHTM, Pech-Canul A, Ziegler SJ, Burgin TE, Richardson ID, Maloney MI, Bomble YJ, Lynd LR, Olson DG.   +8 more
europepmc   +1 more source