Results 61 to 70 of about 710,495 (352)

Structures and functions of mitochondrial ABC transporters [PDF]

open access: yes, 2015
A small number of physiologically important ATP-binding cassette (ABC) transporters are found in mitochondria. Most are half transporters of the B group forming homodimers and their topology suggests they function as exporters.
Aller   +67 more
core   +2 more sources

Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids [PDF]

open access: yes, 2020
This is the pre-peer reviewed version of the following article: Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids, which has been published in final form at https://doi.org/10.1002/slct.201903835.
Carda, Miguel   +6 more
core   +1 more source

Vibrio natriegens as Host for Expression of Multisubunit Membrane Protein Complexes

open access: yesFrontiers in Microbiology, 2018
Escherichia coli is a convenient host for the expression of proteins, but the heterologous production of large membrane protein complexes often is hampered by the lack of specific accessory genes required for membrane insertion or cofactor assembly.
Lena Schleicher   +8 more
doaj   +1 more source

Protein Amphipathic Helix Insertion: A Mechanism to Induce Membrane Fission

open access: yesFrontiers in Cell and Developmental Biology, 2019
One of the fundamental features of biomembranes is the ability to fuse or to separate. These processes called respectively membrane fusion and fission are central in the homeostasis of events such as those related to intracellular membrane traffic ...
Mikhail A. Zhukovsky   +4 more
doaj   +1 more source

CD46 and Oncologic Interactions: Friendly Fire against Cancer

open access: yesAntibodies, 2020
One of the most challenging aspects of cancer therapeutics is target selection. Recently, CD46 (membrane cofactor protein; MCP) has emerged as a key player in both malignant transformation as well as in cancer treatments.
Michelle Elvington   +2 more
doaj   +1 more source

Crystallographic studies of the Escherichia coli quinol-fumarate reductase with inhibitors bound to the quinol-binding site [PDF]

open access: yes, 2002
The quinol-fumarate reductase (QFR) respiratory complex of Escherichia coli is a four-subunit integral-membrane complex that catalyzes the final step of anaerobic respiration when fumarate is the terminal electron acceptor.
Cecchini, Gary   +4 more
core   +1 more source

Reproductive Characteristic of Transgenic Massachusetts General Hospital Miniature Pigs for Xenotransplantation

open access: yesJournal of Animal Reproduction and Biotechnology, 2017
Pigs have been extensively used as mediators of xenotransplantation research. Specifically, the Massachusetts General Hospital (MGH) miniature pig was developed to fix major histocompatibility antigens for use in xenotransplantation studies. We generated
Soo-Jeong Ji   +8 more
doaj   +1 more source

Complement regulator CD46: Genetic variants and disease associations [PDF]

open access: yes, 2015
Membrane cofactor protein (MCP; CD46) is an ubiquitously expressed complement regulatory protein that protects host cells from injury by complement.
Atkinson, John P, Liszewski, M. Kathryn
core   +2 more sources

Current knowledge and recent advances in understanding metabolism of the model cyanobacterium Synechocystis sp. PCC 6803 [PDF]

open access: yes, 2020
Cyanobacteria are key organisms in the global ecosystem, useful models for studying metabolic and physiological processes conserved in photosynthetic organisms, and potential renewable platforms for production of chemicals.
Lea-Smith, David   +2 more
core   +2 more sources

Molecular cloning and chromosomal localization of human membrane cofactor protein (MCP). Evidence for inclusion in the multigene family of complement-regulatory proteins

open access: yesJournal of Experimental Medicine, 1988
Membrane cofactor protein (MCP), a regulatory molecular of the complement system with cofactor activity for the factor I-mediated inactivation of C3b and C4b, is widely distributed, being present on leukocytes, platelets, endothelial cells, epithelial ...
D. Lublin   +8 more
semanticscholar   +1 more source

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