Results 61 to 70 of about 178,051 (334)

Bmcc1s, a novel brain-isoform of Bmcc1, affects cell morphology by regulating MAP6/STOP functions. [PDF]

PLoS ONE, 2012
The BCH (BNIP2 and Cdc42GAP Homology) domain-containing protein Bmcc1/Prune2 is highly enriched in the brain and is involved in the regulation of cytoskeleton dynamics and cell survival.
Jessica Arama, Anne-Cécile Boulay, Christophe Bosc, Christian Delphin, Damarys Loew, Philippe Rostaing, Edwige Amigou, Pascal Ezan, Laure Wingertsmann, Laurent Guillaud, Annie Andrieux, Christian Giaume, Martine Cohen-Salmon   +12 more
doaj   +1 more source

Expression of complement-related membrane proteins on lymphocytes and alveolar macrophages in bronchoalveolar lavage fluid

Allergology International, 1998
Interstitial lung disease (ILD) can be separated into two groups: (i) that in which the causes are known; and (ii) that in which the etiologies have not been determined.
Risa Nakahara, Shuhei Takemura, Hideki Onodera, Yoshihiro Kasamatsu, Nobuyuki Seto, Naoko Ichio, Takashi Doi, Sadanobu Nakanishi, Masayuki Okamoto, Kunio Yanagida, Masahiro Ueda, Masako Deguchi, Motoharu Kondo   +12 more
doaj   +1 more source

Demonstration and characterization of CD46, membrane cofactor protein, in stomach.

Japanese Journal of Clinical Immunology, 1996
CD46, membrane cofactor protein, is a glycoprotein widely present on the cell membranes and is different in molecular weight among organs or cells in the same individual. It acts as a cofactor of I of the complement system, which inactivates C3b bound to the autologous cells, and protects them from the attack of the complement.
N, Seto, S, Takemura, S, Nakanishi, T, Doi, N, Ichio, R, Nakahara, Y, Kasamatsu, K, Yanagida, M, Okamoto, H, Onodera, M, Kondo   +10 more
openaire   +3 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

CD46 Is a Protein Receptor for Human Adenovirus Type 64

Viruses
Certain species D human adenoviruses (HAdV-D19, -D37, and -D64) are causative agents of epidemic keratoconjunctivitis. HAdV-D37 has previously been shown to bind CD46 (membrane cofactor protein) and sialic acid as adhesion receptors.
Eugene Y. Wu, Alexander M. Robertson, Hanglin (Henry) Zhu, Corina Stasiak, Laura A. Murray-Nerger, Emily Romanoff, Jesse Woon, Beth A. Bromme, Jason G. Smith   +8 more
doaj   +1 more source

Intoxication of host cells by the T3SS phospholipase ExoU: PI(4,5)P2-associated, cytoskeletal collapse and late phase membrane blebbing. [PDF]

PLoS ONE, 2014
Pseudomonas aeruginosa is an opportunistic pathogen that is associated with hospital-acquired infections, ventilator-associated pneumonia, and morbidity of immunocompromised individuals. A subpopulation of P.
Hiromi Sato, Dara W Frank
doaj   +1 more source

Complement regulator CD46: Genetic variants and disease associations [PDF]

, 2015
Membrane cofactor protein (MCP; CD46) is an ubiquitously expressed complement regulatory protein that protects host cells from injury by complement.
Atkinson, John P, Liszewski, M. Kathryn
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Long‐term efficacy of encapsulated xenogeneic islet transplantation: Impact of encapsulation techniques and donor genetic traits

Journal of Diabetes Investigation
Aims/Introduction To investigate the long‐term efficacy of various encapsulated xenogeneic islet transplantation, and to explore the impact of different donor porcine genetic traits on islet transplantation outcomes.
Heon‐Seok Park, Eun Young Lee, Young‐Hye You, Marie Rhee, Jong‐Min Kim, Seong‐Soo Hwang, Poong‐Yeon Lee   +6 more
doaj   +1 more source

Rab11-FIP1C and Rab14 direct plasma membrane sorting and particle incorporation of the HIV-1 envelope glycoprotein complex. [PDF]

PLoS Pathogens, 2013
The incorporation of the envelope glycoprotein complex (Env) onto the developing particle is a crucial step in the HIV-1 lifecycle. The long cytoplasmic tail (CT) of Env is required for the incorporation of Env onto HIV particles in T cells and ...
Mingli Qi, Janice A Williams, Hin Chu, Xuemin Chen, Jaang-Jiun Wang, Lingmei Ding, Ehiole Akhirome, Xiaoyun Wen, Lynne A Lapierre, James R Goldenring, Paul Spearman   +10 more
doaj   +1 more source