Results 61 to 70 of about 666,510 (287)
OSBP-related protein family in lipid transport over membrane contact sites [PDF]
, 2015 Peer ...
Olkkonen, V.M.
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Calcium signaling at ER membrane contact sites
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2015 Communication between organelles is a necessary consequence of intracellular compartmentalization. Membrane contact sites (MCSs) are regions where the membranes of two organelles come into close apposition allowing exchange of small molecules and ions including Ca²⁺.
Burgoyne, Thomas +2 more
openaire +2 more sources
Genome Structural-Functional Peculiarities Affecting Plant Epigenetic Variability and Evolution [PDF]
, 2010 There is an attempt to explain some evolutionary processes in plants such as saltatory changes on the base of multidimensionality of plant inherited information coding.
Evgenii Levites
core +1 more source
Tubular lipid binding proteins (TULIPs) growing everywhere [PDF]
, 2017 Tubular lipid binding proteins (TULIPs) have become a focus of interest in the cell biology of lipid signalling, lipid traffic and membrane contact sites.
Levine, TP, Wong, LH
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Peroxisome biogenesis, membrane contact sites, and quality control [PDF]
EMBO reports, 2018 Peroxisomes are conserved organelles of eukaryotic cells with important roles in cellular metabolism, human health, redox homeostasis, as well as intracellular metabolite transfer and signaling. We review here the current status of the different co-existing modes of biogenesis of peroxisomal membrane proteins demonstrating the fascinating adaptability ...
Jean‐Claude Farré +3 more
openaire +5 more sources
Communicative & Integrative Biology, 2017 Endoplasmic Reticulum (ER), spreading in the whole cell cytoplasm, is a central player in eukaryotic cell homeostasis, from plants to mammals. Beside crucial functions, such as membrane lipids and proteins synthesis and outward transport, the ER is able ...
Diana Molino +4 more
doaj +1 more source
VMP1 Establishes ER-Microdomains that Regulate Membrane Contact Sites and Autophagy. [PDF]
PLoS ONE, 2016 The endoplasmic reticulum (ER) regulates organelle dynamics through the formation of membrane contact sites (MCS). Here we describe that VMP1, a multispanning ER-resident protein involved in autophagy, is enriched in ER micro-domains that are in close ...
Luis-Carlos Tábara, Ricardo Escalante
doaj +1 more source
Vitronectin at sites of cell-substrate contact in cultures of rat myotubes [PDF]
, 1986 Affinity-purified antibodies to the serum glycoprotein, vitronectin, were used to study sites of cell-substrate contact in cultures of rat myotubes and fibroblasts.
Baetscher, Manfred +2 more
core +1 more source