Results 11 to 20 of about 2,473,220 (258)

Occurrence of a bacterial membrane microdomain at the cell division site enriched in phospholipids with polyunsaturated hydrocarbon chains. [PDF]

J Biol Chem, 2012
Background: Phospholipids containing polyunsaturated hydrocarbon chains play important roles in various biological membranes. Results: Fluorescence microscopic analysis with a chemically synthesized fluorescent probe showed localization of phospholipids ...
Sato S, Kawamoto J, Sato SB, Watanabe B, Hiratake J, Esaki N, Kurihara T.   +6 more
europepmc   +2 more sources

Fluorescent probes for the visualization of membrane microdomain, deformation, and fusion [PDF]

Smart Molecules
The cell membrane, a fluid interface composed of self‐assembled phospholipid molecules, is a vital component of biological systems that maintains cellular stability and prevents the invasion of foreign toxins.
Pei‐Hong Tong, Tong‐Yuan Wu, Mingle Li, Hai‐Bin Wang, Feng Zheng, Lin Xu, Wei‐Tao Dou   +6 more
doaj   +2 more sources

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT. [PDF]

Nat Neurosci, 2011
Plasmalemmal neurotransmitter transporters (NTTs) regulate the level of neurotransmitters, such as dopamine (DA) and glutamate, after their release at brain synapses.
Cremona ML, Matthies HJ, Pau K, Bowton E, Speed N, Lute BJ, Anderson M, Sen N, Robertson SD, Vaughan RA, Rothman JE, Galli A, Javitch JA, Yamamoto A.   +13 more
europepmc   +2 more sources

Membrane-microdomain localization of amyloid β-precursor protein (APP) C-terminal fragments is regulated by phosphorylation of the cytoplasmic Thr668 residue. [PDF]

J Biol Chem, 2012
Background: Phosphorylation of amyloid β-precursor protein (APP) at Thr668 alters the conformation of its cytoplasmic domain. Results: Phosphorylation of APP C-terminal fragments (pCTFs) at Thr668 decreases membrane lipid binding.
Matsushima T, Saito Y, Elliott JI, Iijima-Ando K, Nishimura M, Kimura N, Hata S, Yamamoto T, Nakaya T, Suzuki T.   +9 more
europepmc   +2 more sources

Structural basis for membrane microdomain formation by a human Stomatin complex [PDF]

Nature Communications
Biological membranes are not just passive barriers—they actively sense and respond to mechanical forces, in part through specialized proteins embedded within them.
Jack Stoner, Shufang Li, Ziao Fu
doaj   +2 more sources

Low cholesterol triggers membrane microdomain-dependent CD44 shedding and suppresses tumor cell migration. [PDF]

J Biol Chem, 2011
CD44 is a cell surface adhesion molecule for hyaluronan and is implicated in tumor invasion and metastasis. Proteolytic cleavage of CD44 plays a critical role in the migration of tumor cells and is regulated by factors present in the tumor ...
Murai T, Maruyama Y, Mio K, Nishiyama H, Suga M, Sato C.   +5 more
europepmc   +2 more sources

Membrane microdomain switching: a regulatory mechanism of amyloid precursor protein processing. [PDF]

J Cell Biol, 2008
Neuronal activity has an impact on β cleavage of amyloid precursor protein (APP) by BACE1 to generate amyloid-β peptide (Aβ). However, the molecular mechanisms underlying this effect remain to be elucidated.
Sakurai T, Kaneko K, Okuno M, Wada K, Kashiyama T, Shimizu H, Akagi T, Hashikawa T, Nukina N.   +8 more
europepmc   +2 more sources

Membrane microdomain may be a platform for immune signaling. [PDF]

Plant Signal Behav, 2012
Qi Y, Katagiri F.
europepmc   +2 more sources

Primary alveolar epithelial cell surface membrane microdomain function is required for Pneumocystis β-glucan-induced inflammatory responses. [PDF]

Innate Immun, 2012
Evans SE, Kottom TJ, Pagano RE, Limper AH.   +3 more
europepmc   +2 more sources

Transforming potential of Src family kinases is limited by the cholesterol-enriched membrane microdomain. [PDF]

Mol Cell Biol, 2009
Oneyama C, Iino T, Saito K, Suzuki K, Ogawa A, Okada M.   +5 more
europepmc   +2 more sources