Results 121 to 130 of about 1,117,893 (276)

Virus Assembly on a Membrane is Facilitated by Membrane Microdomains

, 2014
For many viruses assembly and budding occur simultaneously during virion formation. Understanding the mechanisms underlying this process could promote biomedical efforts to block viral propagation and enable use of capsids in nanomaterials applications.
Ruiz-Herrero, Teresa, Hagan, Michael F.
openaire   +2 more sources

The Membrane Steps of Bacterial Cell Wall Synthesis as Antibiotic Targets [PDF]

, 2016
Peptidoglycan is the major component of the cell envelope of virtually all bacteria. It has structural roles and acts as a selective sieve for molecules from the outer environment. Peptidoglycan synthesis is therefore one of the most important biogenesis
Eefjan Breukink, Liu, Yao, Breukink, Eefjan, Yao Liu, Sub Membrane Biochemistry & Biophysics, Membrane Biochemistry and Biophysics   +5 more
core   +1 more source

Hypothesis: could the signalling function of membrane microdomains involve a localized transition of lipids from liquid to solid state?

BMC Cell Biology, 2004
Background Over the past decade, it has become apparent that specialised membrane microdomains, commonly called rafts, where lipids like sphingolipids and cholesterol are arranged compactly in a liquid ordered phase are involved in cell signalling ...
Joly Etienne
doaj   +1 more source

Unmasking Glycoforms: Lectin‐Based Profiling and Functional Implications of Targeted Glycosylation Knockouts in Chinese Hamster Ovary Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Monoclonal antibody (mAb) glycosylation is a critical quality attribute that is difficult to rationally engineer and rapidly assess during cell line development. Here, we investigate whether cell‐surface glycosylation can serve as a surrogate readout of mAb product glycosylation following targeted glycogene engineering in CHO cells.
Cristina Abascal Ruiz, Sheryl Li Yan Lim, Jacobus Brink, Sara Carillo, Eoin Casey, Jonathan Bones, Ioscani Jiménez del Val   +6 more
wiley   +1 more source

Detergent-resistant plasma membrane proteomes for elucidating microdomain functions in plant cells

Frontiers in Plant Science, 2013
Although proteins and lipids have been assumed to be distributed homogeneously in the plasma membrane (PM), recent studies suggest that the PM is non-uniform, forming a structure that includes a number of lateral domains enriched in specific components ...
Daisuke eTakahashi, Yukio eKawamura, Yukio eKawamura, Matsuo eUemura, Matsuo eUemura   +4 more
doaj   +1 more source

Role of Glycosphingolipids in Formation and Function of Membrane Microdomains

Trends in Glycoscience and Glycotechnology, 2001
Recent years have been characterized by a huge interest in the structure and function of mammalian cell membrane lipid domains. The interest in this subject grew further, when their participation in important membrane-associated events such as signal transmission, cell adhesion and lipid/protein sorting was postulated. A common feature of cell membrane
M. Masserini, D. Ravasi, S. Sonnino
openaire   +2 more sources

Tetraspanin‐ESCRT sorting drives miR‐29b packaging into extracellular vesicles to reverse fibrosis in intrauterine adhesions

BMEMat, EarlyView.
MiR‐29b is enriched in extracellular vesicles (EVs) via a tetraspanin transporter‐dependent endocytosis and sorting complex required for the endosomal transport (ESCRT)‐dependent pathway. These EVs target the 3′ untranslated region (3′UTR) of TGFB2, thereby inhibiting the TGF‐β/Smad3 signaling pathway and repairing endometrial damage in intrauterine ...
Lihao Chen, Jianfeng Wu, Shunhan Zhang, Siqi Huang, Yingjun Xie, Hongda Chen, Yinghong Yang, Lan Xiao, Ding Wang, Keke Wu, Xiaofang Sun   +10 more
wiley   +1 more source

Mitochondria‐endoplasmic reticulum organelle glue as maturation promoter for origination/dimensional dual‐cross cardiomyocytes

BMEMat, EarlyView.
Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang, Hao Sun, Chenqi Duan, Jiajia Chang, Yuxing Wang, Ming Zhao, Huiyue Zhao, Shan Lu, Yang Yang, Da Huo   +9 more
wiley   +1 more source

Biopolymer composites from agri‐food wastes and by‐products: valorization, fabrication, and food related applications

Food Biomacromolecules, EarlyView.
Agri‐food wastes and by‐products are transformed into sustainable biopolymer composites through extraction, modification, and advanced fabrication technologies. These value‐added materials exhibit enhanced mechanical, barrier, antimicrobial, and biodegradable properties, enabling applications in food packaging, edible coatings, and preservation systems
Samuel Ayofemi Olalekan Adeyeye, Blessing Rachael Adeyeye   +1 more
wiley   +1 more source

Plasma membrane microdomains in plants: for which physiological roles?

, 2007
International audienceA large body of evidence supports the existence, in membrane from animal and yeast cells, of functional microdomains playing important roles in protein sorting, signal transduction, or infection by pathogens (1). We demonstrated the
Simon-Plas, Françoise, Morel, Johanne, Mongrand, Sebastien, Vesa, Simona-Maria   +3 more
core   +1 more source