Results 121 to 130 of about 34,175 (279)

Membrane microdomains in hepatocytes: potential target areas for proteins involved in canalicular bile secretion

Journal of Lipid Research, 2005
The formation of hepatic bile requires that water be transported across liver epithelia. Rat hepatocytes express three aquaporins (AQPs): AQP8, AQP9, and AQP0. Recognizing that cholesterol and sphingolipids are thought to promote the assembly of proteins
P. Tietz, J. Jefferson, R. Pagano, N.F. LaRusso   +3 more
doaj   +1 more source

Interfacial Proton‐Relay Microenvironment Enables Self‐Driven Singlet Oxygen Generation under Neutral Conditions

Advanced Science, EarlyView.
An interfacial proton‐relay microenvironment at MoS2‐CuCl heterostructures enables selective O2 activation to 1O2 under neutral conditions. Electron‐deficient sulfur sites mediate proton transfer to Cu‐bound O2, accelerating *OOH hydrogenation while suppressing O─O bond cleavage, achieving stable, efficient pollutant removal.
Qiaoyu Gao, Xiaohui Dai, Jian Ye, Lili Li, Chenxiao Yu, Yuehan Jiang, Jiangdong Dai, Xiaohua Tian, Jun Zhao, Jianming Pan   +9 more
wiley   +1 more source

Partitioning into ER membrane microdomains impacts autophagic protein turnover during cellular aging

Scientific Reports
Eukaryotic membranes are compartmentalized into distinct micro- and nanodomains that rearrange dynamically in response to external and internal cues. This lateral heterogeneity of the lipid bilayer and associated clustering of distinct membrane proteins ...
Simon Prokisch, Sabrina Büttner
doaj   +1 more source

Stiffness‐Activated Stellate Cells Drive Pancreatic Cancer Liver Colonization via GMFG‐TNS4 Signaling

Advanced Science, EarlyView.
Fibrotic liver stiffness activates hepatic stellate cells through Piezo1‐dependent calcium influx and ER stress, promoting EV‐associated GMFG release. Delivered GMFG engages TNS4 in pancreatic cancer cells, triggering FAK/AKT signaling, adhesion, and fatty acid synthesis.
Biwen Zhu, Jian Wan, Xue Zhang, Jiashuai Yan, Xi Chen, Xiaoqi Guan, Qianqian Ren, Tao Yang, Di Wu, Qingsong Guo, Yibing Guo, Yuhua Lu   +11 more
wiley   +1 more source

Natural Anionic Interfacial Reconstruction for Suppressing Pitting Corrosion Enables Durable Seawater Zinc‐Ion Batteries

Advanced Energy Materials, EarlyView.
In situ electrochemically induced molecular sieve‐alginate interface layer can suppress chloride‐induced pitting corrosion, hydrogen evolution, and dendrite growth, while regulating zinc ion transport and deposition, thereby protecting the zinc anode in seawater electrolyte.
Yunpeng Zhong, Xuhuan Xiao, Xueru Shi, Haochen Li, Zeshi Li, Zhaohan Wu, Ivan P. Parkin, Guanjie He   +7 more
wiley   +1 more source

T lymphocyte costimulation mediated by reorganization of membrane microdomains

, 1999
Although dispensable, costimulation through CD28 facilitates activation of naïve T lymphocytes. CD28 engagement led to the redistribution and clustering of membrane and intracellular kinase-rich raft microdomains at the site of T cell receptor (TCR ...
Lanzavecchia, A, Sakakibara, Y, S. Schroeder, Susanne Schroeder, Antonio Lanzavecchia, Viola, A, Schroeder, S, Y. Sakakibara, A. Lanzavecchia, Antonella Viola, A. Viola, Yoichi Sakakibara   +11 more
core   +1 more source

Biomarkers of Sarcopenia: Current Status and Future Perspectives

AGING MEDICINE, EarlyView.
In this review, we summarize the various biomarkers discovered in recent years, including biochemical, imaging, and physical testing markers. We analyze their advantages and disadvantages and propose potential ways to improve the diagnostic accuracy of biomarkers, as well as future research directions.
Bijin Luo, Wenhan Li, Yi Zhang, Mengchen Liu, Kemeng Zhang, Sui Huang, Ping He   +6 more
wiley   +1 more source

Hypothesis: could the signalling function of membrane microdomains involve a localized transition of lipids from liquid to solid state?

BMC Cell Biology, 2004
Background Over the past decade, it has become apparent that specialised membrane microdomains, commonly called rafts, where lipids like sphingolipids and cholesterol are arranged compactly in a liquid ordered phase are involved in cell signalling ...
Joly Etienne
doaj   +1 more source

Virus Assembly on a Membrane is Facilitated by Membrane Microdomains

, 2014
For many viruses assembly and budding occur simultaneously during virion formation. Understanding the mechanisms underlying this process could promote biomedical efforts to block viral propagation and enable use of capsids in nanomaterials applications.
Ruiz-Herrero, Teresa, Hagan, Michael F.
openaire   +2 more sources

Role of Glycosphingolipids in Formation and Function of Membrane Microdomains

Trends in Glycoscience and Glycotechnology, 2001
Recent years have been characterized by a huge interest in the structure and function of mammalian cell membrane lipid domains. The interest in this subject grew further, when their participation in important membrane-associated events such as signal transmission, cell adhesion and lipid/protein sorting was postulated. A common feature of cell membrane
M. Masserini, D. Ravasi, S. Sonnino
openaire   +2 more sources