Sphingolipids: membrane microdomains in brain development, function and neurological diseases [PDF]
Open Biology, 2017 Sphingolipids are highly enriched in the nervous system where they are pivotal constituents of the plasma membranes and are important for proper brain development and functions. Sphingolipids are not merely structural elements, but are also recognized as
Anne S. B. Olsen, Nils J. Færgeman
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Analysis of lipid-composition changes in plasma membrane microdomains[S] [PDF]
Journal of Lipid Research, 2015 Sphingolipids accumulate in plasma membrane microdomain sites, such as caveolae or lipid rafts. Such microdomains are considered to be important nexuses for signal transduction, although changes in the microdomain lipid components brought about by ...
Hideo Ogiso +2 more
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Revisiting Membrane Microdomains and Phase Separation: A Viral Perspective. [PDF]
Viruses, 2020 Sengupta P, Lippincott-Schwartz J.
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Analysis of Lipids, Fatty Acid, and Cholesterol in Membrane Microdomains. [PDF]
Methods Mol Biol, 2023 Agbaga MP, McClellan ME, Elliott MH.
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Exploring functional membrane microdomains in bacteria: an overview. [PDF]
Curr Opin Microbiol, 2017 Lopez D, Koch G.
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Anterior-enriched filopodia create the appearance of asymmetric membrane microdomains in polarizing <i>C. elegans</i> zygotes. [PDF]
J Cell Sci, 2019 Hirani N +6 more
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Spatio-temporal remodeling of functional membrane microdomains organizes the signaling networks of a bacterium. [PDF]
PLoS Genetics, 2015 Lipid rafts are membrane microdomains specialized in the regulation of numerous cellular processes related to membrane organization, as diverse as signal transduction, protein sorting, membrane trafficking or pathogen invasion.
Johannes Schneider +8 more
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The transmembrane region is responsible for targeting of adaptor protein LAX into "heavy rafts". [PDF]
PLoS ONE, 2012 BACKGROUND: The importance of membrane compartmentalization into specific membrane microdomains has been shown in many biological processes such as immunoreceptor signaling, membrane trafficking, pathogen infection, and tumor progression.
Matous Hrdinka +2 more
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The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains
eLife, 2021 Sigma 1 receptor (S1R) is a 223-amino-acid-long transmembrane endoplasmic reticulum (ER) protein. S1R modulates activity of multiple effector proteins and is a well-established drug target.
Vladimir Zhemkov +6 more
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Journal of Lipid Research, 2001 The hypothesis of lipid domains in cellular plasma membranes is well established. However, direct visualization of the domains has been difficult. Here we report direct visualization of plasma membrane cholesterol microdomains modulated by agents that ...
Howard S. Kruth +5 more
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