Results 21 to 30 of about 58,466 (172)

Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation. [PDF]

, 2001
Recent studies indicate that insulin stimulation of glucose transporter (GLUT)4 translocation requires at least two distinct insulin receptor-mediated signals: one leading to the activation of phosphatidylinositol 3 (PI-3) kinase and the other to the ...
Chiang, SH, Kanzaki, M, Macara, IG, Mora, S, Pessin, JE, Saltiel, AR, Shigematsu, S, Watson, RT   +7 more
core   +3 more sources

Role of mitochondrial raft-like microdomains in the regulation of cell apoptosis [PDF]

, 2015
Lipid rafts are envisaged as lateral assemblies of specific lipids and proteins that dissociate and associate rapidly and form functional clusters in cell membranes.
A Al-Saif, A Bertoni, A Cossarizza, A Ferri, A Israelson, A Raturi, A Valencia, A Valencia, AA Rowland, AE Rusinol, AL Nishimura, AL Wozniak, Alberto Ferri, AM Giammarioli, AO Hueber, B Kornmann, C Barbat, C Brooks, C Dall’Armi, C Frezza, C Gajate, C Garcia-Ruiz, C Garcia-Ruiz, C Martel, C Steinmann, C Vande Velde, CB Pickett, CD Austin, CH Chou, CL Schengrund, D Naon, D Scheel-Toellner, D Scheel-Toellner, DF Legler, DF Suen, DT Browman, E Bossy-Wetzel, E Lai, E Szegezdi, EM Lynes, EM Lynes, F Korobova, F Mollinedo, G Csordas, G Szabadkai, GC Shore, GM Cereghetti, H Grassmè, H Yano, I Annunziata, I Poggiolini, J Faitova, J Katz, J Stiban, JC Martinou, JC Wanson, JE Vance, JL Herrera, JR Friedman, JT Vollrath, K Banki, K Simons, K Simons, KF Ferri, KR Pitts, L Ciarlo, L Ciarlo, L Dupuis, L Scorrano, LA Lewis, M Cozzolino, M Cozzolino, M Degli Esposti, M Degli Esposti, M Fujimoto, M Hamasaki, M Hamasaki, M Karbowski, M Lutter, M Satoh, M Sorice, M Sorice, M Sorice, M Sorice, M Sorice, M Vey, Maria Grasso, Maurizio Sorice, ME Soriano, MG Martín, MM Young, MR Rippo, MT Dimanche-Boitre, N Myhill, N Naslavsky, N Zurgil, NT Watt, OM Brito de, OM Brito de, P Matarrese, P Matarrese, P Matarrese, P Pizzo, P Pizzo, P Pizzo, PA Parone, PJ Meier, R Rizzuto, R Rizzuto, R Sano, R Stoica, RG Burns, RM Siegel, Roberta Misasi, S Ayala-Peña, S Cipolat, S Eda, S Hoppins, S Montessuit, S Orrenius, S Ouasti, S Sonnino, SB Prusiner, SW Ahn, SY Gilady, T Garofalo, T Garofalo, T Gutierrez, T Hayashi, T Hayashi, T Hayashi, T Hayashi, T Kuwana, T Simmen, T Simmen, Tina Garofalo, UP Shirendeb, V Lallemand-Breitenbach, V Mattei, V Mattei, V Mattei, Valeria Manganelli, Vincenzo Mattei, W Hu, W Malorni, W Song, W Song, X Guo, Y Higuchi, Y Yoon, Y Zhang, YJ Lee, Z Sui, Z Wieslaw   +153 more
core   +1 more source

Reversible Dissolution of Microdomains in Detergent-Resistant Membranes at Physiological Temperature. [PDF]

PLoS ONE, 2015
The formation of lipid microdomains ("rafts") is presumed to play an important role in various cellular functions, but their nature remains controversial.
Andrea Cremona, Francesco Orsini, Paola A Corsetto, Bart W Hoogenboom, Angela M Rizzo   +4 more
doaj   +1 more source

Evidence for the involvement of lipid rafts localized at the ER-mitochondria associated membranes in autophagosome formation [PDF]

, 2016
Mitochondria-associated membranes (MAMs) are subdomains of the endoplasmic reticulum (ER) that interact with mitochondria. This membrane scrambling between ER and mitochondria appears to play a critical role in the earliest steps of autophagy.
Faggioni, Alberto, Gambardella, Lucrezia, Garofalo, Tina, Malorni, Walter, Manganelli, Valeria, Marconi, Matteo, Matarrese, Paola, Misasi, Roberta, Sorice, Maurizio, Tinari, Antonella   +9 more
core   +2 more sources

Nanoclustering as a dominant feature of plasma membrane organization [PDF]

, 2014
Early studies have revealed that some mammalian plasma membrane proteins exist in small nanoclusters. The advent of super-resolution microscopy has corroborated and extended this picture, and led to the suggestion that many, if not most, membrane ...
Cambi, Alessandra, García-Parajo, María F., Jacobson, Ken, Thomoson, Nancy, Torreño-Piña, Juan A.   +4 more
core   +5 more sources

T cell Ca2+ microdomains through the lens of computational modeling

Frontiers in Immunology, 2023
Cellular Ca2+ signaling is highly organized in time and space. Locally restricted and short-lived regions of Ca2+ increase, called Ca2+ microdomains, constitute building blocks that are differentially arranged to create cellular Ca2+ signatures ...
Diana C. Gil Montoya, Roberto Ornelas-Guevara, Björn-Philipp Diercks, Andreas H. Guse, Geneviève Dupont   +4 more
doaj   +1 more source

Use of dansyl-cholestanol as a probe of cholesterol behavior in membranes of living cells[S]

Journal of Lipid Research, 2010
While plasma membrane cholesterol-rich microdomains play a role in cholesterol trafficking, little is known about the appearance and dynamics of cholesterol through these domains in living cells.
Huan Huang, Avery L. McIntosh, Barbara P. Atshaves, Yoshiko Ohno-Iwashita, Ann B. Kier, Friedhelm Schroeder   +5 more
doaj   +1 more source

Glycosphingolipid GM3 is localized in both exoplasmic and cytoplasmic leaflets of Plasmodium falciparum malaria parasite plasma membrane

Scientific Reports, 2021
Lipid rafts, sterol-rich and sphingolipid-rich microdomains on the plasma membrane are important in processes like cell signaling, adhesion, and protein and lipid transport.
Shiomi Koudatsu, Tatsunori Masatani, Rikako Konishi, Masahito Asada, Hassan Hakimi, Yuna Kurokawa, Kanna Tomioku, Osamu Kaneko, Akikazu Fujita   +8 more
doaj   +1 more source

Caveolin is present in intestinal cells: role in cholesterol trafficking?

Journal of Lipid Research, 1998
It was postulated that specialized microdomains of the plasma membrane, consistent with caveolae, might play a role in cholesterol trafficking in intestinal cells.
F. Jeffrey Field, Ella Born, Shubha Murthy, Satya N. Mathur   +3 more
doaj   +1 more source

Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes [PDF]

, 2016
Desmosomes are adhesion plaques that mediate cell-cell adhesion in many tissues, including the epidermis, and generate mechanical resistance to tissues. The extracellular domains of desmosomal cadherin proteins, desmogleins and desmocollins, are required
Ali, Jawahir, Banning, Antje, Eming, Rüdiger, Exner, Yvonne, Hertl, Michael, Kurrle, Nina, Tikkanen, Ritva, Völlner, Frauke   +7 more
core   +1 more source