Results 71 to 80 of about 29,523 (243)

The Role of Lipids in Retrovirus Replication

open access: yesViruses, 2010
Retroviruses undergo several critical steps to complete a replication cycle. These include the complex processes of virus entry, assembly, and budding that often take place at the plasma membrane of the host cell.
Abdul A. Waheed, Eric O. Freed
doaj   +1 more source

The Mitochondrial Ca(2+) Uniporter: Structure, Function, and Pharmacology. [PDF]

open access: yes, 2017
Mitochondrial Ca(2+) uptake is crucial for an array of cellular functions while an imbalance can elicit cell death. In this chapter, we briefly reviewed the various modes of mitochondrial Ca(2+) uptake and our current understanding of mitochondrial Ca(2+)
A Quintana   +167 more
core   +2 more sources

Mussel‐Inspired Molecular Strategies for Fabricating Functional Materials With Underwater Adhesion and Self‐Healing Properties

open access: yesAdvanced Materials, EarlyView.
This review systematically examines the nanomechanical mechanisms of mussel‐inspired molecular interactions, primarily investigated by direct force measurement techniques such as surface forces apparatus and atomic force microscopy. The macroscopic adhesive and self‐healing performances of mussel‐inspired functional materials, including coacervates ...
Pan Huang, Hongjian Zhang, Hongbo Zeng
wiley   +1 more source

Proteomic and Targeted Lipidomic Analyses of Fluid and Rigid Rubber Particle Membrane Domains in Guayule

open access: yesPlants
Rubber (cis-1,4-polyisoprene) is produced in cytosolic unilamellar vesicles called rubber particles (RPs), and the protein complex responsible for this synthesis, the rubber transferase (RTase), is embedded in, or tethered to, the membranes of these RPs.
Joshua J. Blakeslee   +7 more
doaj   +1 more source

Plant Sterol Clustering Correlates with Membrane Microdomains as Revealed by Optical and Computational Microscopy

open access: yesMembranes, 2021
Local inhomogeneities in lipid composition play a crucial role in the regulation of signal transduction and membrane traffic. This is particularly the case for plant plasma membrane, which is enriched in specific lipids, such as free and conjugated forms
Ling Tang   +4 more
doaj   +1 more source

The organisation and functions of local Ca2+ signals [PDF]

open access: yes, 2001
Calcium (Ca2+) is a ubiquitous intracellular messenger, controlling a diverse range of cellular processes, such as gene transcription, muscle contraction and cell proliferation.
Berridge, Michael J.   +2 more
core  

Acid Sphingomyelinase Regulates the Localization and Trafficking of Palmitoylated Proteins [PDF]

open access: yes, 2019
In human, loss of Acid Sphingomeylinase (ASM/SMPD1) causes Niemann-Pick Disease, type A. ASM hydrolyzes sphingomyelins to produce ceramides but protein targets of ASM remain largely unclear. ...
Kim, Yongsoon   +7 more
core   +2 more sources

Practical Considerations in the Design and Use of Non‐Crystalline Metal–Organic Frameworks

open access: yesAdvanced Materials, EarlyView.
This review explores the emerging field of non‐crystalline MOFs ‐ amorphous, liquid, and glassy forms ‐ highlighting how they differ from traditional crystalline MOFs. It discusses their unique synthesis strategies, fundamental principles, and diverse applications.
Hamidreza Mahdavi   +8 more
wiley   +1 more source

Phosphodiesterases 4B and 4D Differentially Regulate cAMP Signaling in Calcium Handling Microdomains of Mouse Hearts

open access: yesCells
The ubiquitous second messenger 3′,5′-cyclic adenosine monophosphate (cAMP) regulates cardiac excitation-contraction coupling (ECC) by signaling in discrete subcellular microdomains.
Axel E. Kraft   +7 more
doaj   +1 more source

Lck, membrane microdomains and TCR triggering machinery: defining the new rules of engagement

open access: yesFrontiers in Immunology, 2012
In spite of a comprehensive understanding of the schematics of T cell receptor (TCR) signaling, the mechanisms regulating compartmentalization of signaling molecules, their transient interactions and rearrangement of membrane structures initiated upon ...
Dominik eFilipp   +2 more
doaj   +1 more source

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