Results 21 to 30 of about 47,795 (200)
BMC Evolutionary Biology, 2007 Background In membrane trafficking, the mechanisms ensuring vesicle fusion specificity remain to be fully elucidated. Early models proposed that specificity was encoded entirely by SNARE proteins; more recent models include contributions from Rab ...
Coulson Richard MR +3 more
doaj +1 more source
A distinct tethering step is vital for vacuole membrane fusion
eLife, 2014 Past experiments with reconstituted proteoliposomes, employing assays that infer membrane fusion from fluorescent lipid dequenching, have suggested that vacuolar SNAREs alone suffice to catalyze membrane fusion in vitro.
Michael Zick, William T Wickner
doaj +1 more source
Scientific Reports, 2017 Homotypic fusion of endoplasmic reticulum membranes is driven by atlastin GTPases; however, the underlying mechanism remains largely unknown. Here, using a FRET-based single-vesicle fusion assay with liposomes bearing the yeast atlastin Sey1p, we ...
Kyung Tae Kim +6 more
doaj +1 more source
The Golgin Family of Coiled-Coil Tethering Proteins
Frontiers in Cell and Developmental Biology, 2016 The golgins are a family of predominantly coiled-coil proteins that are localized to the Golgi apparatus. Golgins are present in all eukaryotes, suggesting an evolutionary conserved function.
Tomasz M Witkos, Martin eLowe
doaj +1 more source
CAPS and Munc13: CATCHRs that SNARE vesicles
Frontiers in Endocrinology, 2013 . CAPS (Calcium-dependent Activator Protein for Secretion, aka CADPS) and Munc13 (Mammalian Unc-13) proteins function to prime vesicles for Ca2+-triggered exocytosis in neurons and neuroendocrine cells.
Declan J James, Thomas F J Martin
doaj +1 more source
Armadillo motifs involved in vesicular transport. [PDF]
PLoS ONE, 2010 Armadillo (ARM) repeat proteins function in various cellular processes including vesicular transport and membrane tethering. They contain an imperfect repeating sequence motif that forms a conserved three-dimensional structure.
Harald Striegl +2 more
doaj +1 more source
Recent Advances in Membrane Shaping for Plant Autophagosome Biogenesis
Frontiers in Plant Science, 2020 Autophagy is an intracellular degradation process, which is highly conserved in eukaryotes. During this process, unwanted cytosolic constituents are sequestered and delivered into the vacuole/lysosome by a double-membrane organelle known as an ...
Cheuk-Ling Wun +2 more
doaj +1 more source
Direct observation of molecular arrays in the organized smooth endoplasmic reticulum
BMC Cell Biology, 2009 Background Tubules and sheets of endoplasmic reticulum perform different functions and undergo inter-conversion during different stages of the cell cycle.
Korkhov Vladimir M, Zuber Benoît
doaj +1 more source
Bioscience Reports, 2012 We have investigated the interaction between GH (growth hormone) and GHR (GH receptor). We previously demonstrated that a truncated GHR that possesses a transmembrane domain but no cytoplasmic domain blocks receptor signalling.
François Guesdon +8 more
doaj +1 more source
Frontiers in Endocrinology, 2013 Dysregulation of regulated exocytosis is linked to an array of pathological conditions, including neurodegenerative disorders, asthma and diabetes. Understanding the molecular mechanisms underpinning neuroexocytosis including the processes that allow ...
Andreas ePapadopulos +3 more
doaj +1 more source