Results 91 to 100 of about 2,522,691 (166)

Bilateral granulosa cell tumors: a novel malignant manifestation of multiple endocrine neoplasia 1 syndrome found in a patient with a rare menin in-frame deletion

The Application of Clinical Genetics, 2015
Michael J Hall,1 Julie Innocent,2 Christina Rybak,1 Colleen Veloski,3 Walter J Scott,4 Hong Wu,5 John A Ridge,4 John P Hoffman,4 Hossein Borghaei,2 Aruna Turaka,6 Mary B Daly1 1Department of Clinical Genetics, 2Department of Medical Oncology, 3Department
Hall MJ, Innocent J, Rybak C, Veloski C, Scott WJ, Wu H, Ridge JA, Hoffman JP, Borghaei H, Turaka A, Daly MB   +10 more
doaj  

Evaluating the role of MEN1 gene expression and its clinical significance in breast cancer patients. [PDF]

PLoS One, 2023
Massey S, Khan MA, Rab SO, Mustafa S, Khan A, Malik Z, Shaik R, Verma MK, Deo S, Husain SA.   +9 more
europepmc   +1 more source

A Novel Pathogenic MEN1 Gene Variant Identified in a Family With Multiple Pancreatic Neuroendocrine Tumors. [PDF]

JCEM Case Rep, 2023
Horikoshi H, Arita J, Hasegawa K, Makita N.   +3 more
europepmc   +1 more source

Two novel mutations in the MEN1 gene in subjects with multiple endocrine neoplasia-1

, 2006
Multiple endocrine neoplasia type 1 (MEN1) is characterized by parathyroid, enteropancreatic endocrine and pituitary adenomas as well as germline mutation of the MEN1 gene. We describe 2 families with MEN1 with novel mutations in the MEN1 gene.
Akdeniz, N., Ozturk, M., Chang, S. C., Hsa, C. Y., Jap, T. S., Chiu, C. Y., Jenq, S. F.   +6 more
core   +1 more source

Identification of somatic mutations of the MEN1 gene in sporadic endocrine tumours

, 2000
Endocrine tumours of the pancreas, anterior pituitary or parathyroids arise either sporadically in the general population, or as a part of inherited syndromes such as multiple endocrine neoplasia type 1 (MEN 1).
S Grimmond, C Boothroyd, M Walters, Palmer, J., L Bergman, N Hayward, Hartley, L, Walters, M., Hayward, N., Hayward, N, Teh, B, J Shepherd, Boothroyd, C, Hartley, L., Teh, B., Boothroyd, C., B Teh, Bergman, L., Grimmond, S., L Hartley, Palmer, J, Walters, M, Shepherd, J, Bergman, L, Grimmond, S, Shepherd, J., J Palmer   +26 more
core   +1 more source

PDP type brain tumor in association with multiple endocrine neoplasia type 1

Heliyon
Multiple endocrine neoplasia type 1 (MEN1) is a rare autosomal dominant syndrome caused by inactivating pathogenic variants in the tumor suppressor gene menin 1 on chromosome 11q13 (Falchetti et al., 2009).
Halldór Bjarki Einarsson, Anja Lisbeth Frederiksen, Inge Soekilde Pedersen, Marianne Schmidt Ettrup, Martin Wirenfeldt, Henning Boldt, Nina Nguyen, Marianne Skovsager Andersen, Carsten Reidies Bjarkam, Frantz Rom Poulsen   +9 more
doaj   +1 more source

MEN1 gene alterations do not correlated with the pèhenotype of sporadic primary hyperparathyroidism

, 2002
: Loss of heterozygosity (LOH) in the MEN1 region on chromosome 11q13 and MEN1 gene mutations have been found in a subset of sporadic parathyroid tumors.
VIGNALI E., CIANFEROTTI, LUISELLA, MICCOLI, PAOLO, CETANI F., PINCHERA, ALDO, AMBROGINI E., PARDI, ELENA, PICONE, ANGELO, BORSARI, SIMONA, MARCOCCI, CLAUDIO   +9 more
core  

A MEN1 syndrome with a paraganglioma.

, 2014
International audienceGermline mutations of the MEN1 gene cause multiple endocrine neoplasia type 1 (MEN1), an autosomal dominant disorder characterized by tumors of the parathyroids, the pancreas, and the anterior pituitary.
Stéphanie Lopez, Marie-Pierre Teissier, Stéphanie, Lopez, Manuela Delage-Corre, Jamilloux, Yvan, Morgane Pertuit, Anne Barlier, Françoise Archambeaud, Pertuit, Morgane, Barlier, Anne,, Barlier, Anne, A., Muriel Mathonnet, Sophie Galinat, Archambeaud, Françoise, Yvan Jamilloux, Favier, Judith, Judith Favier, Delage-Corre, Manuela, Mathonnet, Muriel, Galinat, Sophie, Teissier, Marie-Pierre   +20 more
core   +1 more source

The European Consortium on MEN1. Mapping of the gene encoding the B56β subunit of protein phosphatase 2A (PPP2R5B) to a 0.5-Mb region of chromosome 11q13 and its exclusion as a candidate gene for multiple endocrine neoplasia type 1 (MEN1)

, 1997
The multiple endocrine neoplasia type 1 (MEN1) locus has been previously localised to 11q13 by combined tumour deletion mapping and recombination studies, and a 0.5-Mb region, flanked by PYGM and D11S449, has been defined. In the course of constructing a
Höppener, JW, Harding, B, Forbes, SA, Wooding, C, Gaudray, P, Anand, R, Weber, G, Thakker, RV, Larsson, C, Calender, A, Bassett, JHD, Lips, CJM, Zhang, CX, Höppener, JWM, Thakker, Rajesh, Lips, CJ, Bassett, JH, Butler, R, Ogilvie, D, Pannett, AAJ, Pannett, AA, Kas, K   +21 more
core   +1 more source

Menin orchestrates corticogenesis via regulation of chromatin accessibility and activation of

Cell Reports
Summary: The development of the mammalian cerebral cortex is tightly regulated by epigenetic mechanisms. However, the role of epigenetic modifications in gene regulation and their impact on neocortical function remain poorly understood.
Shuzhong Wang, Kai Zhuang, Liurong Chen, Dan Can, Huifang Li, Li Zhong, Yibo Qu, Jie Zhang   +7 more
doaj   +1 more source