Results 31 to 40 of about 2,522,691 (166)

Role of MEN1 in B cell acute lymphoblastic leukemia

, 2023
noneB Cell Acute Lymphoblastic Leukemias is a heterogenous group of hematological disorder resulting in an impaired hematopoiesis because of an aberrant proliferation and blocked differentiation of immature lymphocytic cells, causing bone marrow failure.
TELESE, STEFANO
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Genetic and Epigenetic Analysis in Korean Patients with Multiple Endocrine Neoplasia Type 1 [PDF]

Endocrinology and Metabolism, 2014
BackgroundMultiple endocrine neoplasia type 1 (MEN1) is a familial syndrome characterized by the parathyroid, pancreas and pituitary tumors. Parathyroid tumors are the most common clinical manifestations, occurring in more than 90% of MEN1 patients ...
Yoon Jung Chung, Sena Hwang, Jong Ju Jeong, Sun Yong Song, Se Hoon Kim, Yumie Rhee   +5 more
doaj   +1 more source

Multiple Endocrine Neoplasia Type 1 (MEN1)

, 2010
This chapter focuses on multiple endocrine neoplasia type 1 (MEN1) which is an autosomal dominantly inherited syndrome. The syndrome is characterized by the occurrence of tumors of the parathyroid glands, the pancreatic islets, the anterior pituitary ...
Cornelis J.M. Lips, van Nesselrooij, Bernadette P M, Höppener, Jo W M, van der Luijt, Rob B., Koen M.A. Dreijerink, Rob B. van der Luijt, Dreijerink, Koen M A, Jo W.M. Höppener, Lips, Cornelis J M, Bernadette P.M. van Nesselrooij   +9 more
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Diagnosis and Management of Multiple Endocrine Neoplasia Type 1 (MEN1)

Hereditary Cancer in Clinical Practice, 2005
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominantly inherited disorder, characterised by the occurrence of tumours of the parathyroid glands, the pancreatic islets, the pituitary gland, the adrenal glands and neuroendocrine carcinoid ...
Dreijerink Koen MA, Lips Cees JM
doaj   +1 more source

Allelic deletion of the MEN1 gene in duodenal gastrin and somatostatin cell neoplasms and their precursor lesions

, 2007
BACKGROUND: Patients with a multiple endocrine neoplasia type 1 (MEN1)-associated Zollinger-Ellison syndrome (ZES) show multifocal duodenal gastrinomas and precursor lesions.AIMS: To test these lesions for loss of heterozygosity (LOH) of the MEN1 gene ...
Gimm, O, Komminoth, P, Schmitt, A,, Perren, A,, Henopp, T, Anlauf, M, Weihe, E,, Dralle, H, Perren, Aurel, Knoefel, W T,, Raffel, A, Kloppel, G, Heitz, P. U, Garbrecht, N, Gimm, O,, Anlauf, M,, Rudolf, T,, Garbrecht, N,, Weihe, E, Klöppel, G,, Henopp, T,, Raffel, A,, Schmitt, A, Rudolf, T, Dralle, H,, Knoefel, W T, Heitz, Ph U,, Komminoth, P,   +27 more
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Novel association of MEN1 gene mutations with parathyroid carcinoma [PDF]

, 2017
Inactivating mutations of the multiple endocrine neoplasia 1 (MEN1) gene cause MEN1 syndrome, characterized by primary hyperparathyroidism (pHPT), and parathyroid and gastro-entero-pancreatic pituitary tumors.
Filomena Cetani, Cetani, Filomena, Hendy, Geoffrey N., Cinque, Luigia, Maiello, Evaristo, Geoffrey N. Hendy, Battista, Claudia, D'Agruma, Leonardo, Celeste Clemente, Chetta, Massimiliano, Angelo Sparaneo, Coco, Michelina, Luigia Cinque, Claudio Marcocci, Claudia Battista, Elena Pardi, Eliana Sanpaolo, Michelina Coco, MARCOCCI, CLAUDIO, Alfredo Scillitani, Evaristo Maiello, Massimiliano Chetta, Teresa Balsamo, David E.C. Cole, Sanpaolo, Eliana, PARDI, ELENA, Sparaneo, Angelo, Clemente, Celeste, Vito Guarnieri, Guarnieri, Vito, Cole, David E. C., Scillitani, Alfredo, Leonardo D'Agruma, Balsamo, Teresa   +33 more
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Characterisation of prostate cancer lesions in heterozygous Men1 mutant mice

BMC Cancer, 2010
Background Mutations of the MEN1 gene predispose to multiple endocrine neoplasia type 1 (MEN1) syndrome. Our group and others have shown that Men1 disruption in mice recapitulates MEN1 pathology.
Tong Wei-Ming, Lu Jieli, Carreira Christine, Fontanière Sandra, Seigne Christelle, Fontanière Bernard, Wang Zhao-Qi, Zhang Chang, Frappart Lucien   +8 more
doaj   +1 more source

Cutaneous lesions and other non-endocrine manifestations of Multiple Endocrine Neoplasia type 1 syndrome

Frontiers in Endocrinology, 2023
BackgroundMultiple Endocrine Neoplasia type 1 is a rare genetic syndrome mainly caused by mutations of MEN1 gene and characterized by a combination of several endocrine and non-endocrine manifestations.
Laura Pierotti, Elena Pardi, Elisa Dinoi, Paolo Piaggi, Simona Borsari, Simone Della Valentina, Chiara Sardella, Angela Michelucci, Maria Adelaide Caligo, Fausto Bogazzi, Claudio Marcocci, Claudio Marcocci, Filomena Cetani   +12 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Identification of the multiple endocrine neoplasia type 1 (MEN1) gene. The European Consortium on MEN1.

, 1997
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterised by tumours of the parathyroids, pancreas and anterior pituitary that represents one of the familial cancer syndromes.
Quincey, D, Höppener, JW, Gaudray, P, Weber, G, Calender, A, Thakker, RV, Lenoir, G, Bassett, JHD, Zhang, CX, Teh, BT, Parente, F, Thakker, Rajesh, Van de Ven, WJ, Hayward, N, DeWitte, K, De Witte, K, De Wit, MJ, Giraud, S, Farnebo, F, Wautot, V, Khodaei, S, Phelan, C, Hoppener, JWM, Forbes, SA, Larsson, C, Lips, CJM, Buisson, N, Pugeat, M, Grant, AL, Lips, CJ, DeWit, MJ, Lemmens, I, Kytölä, S, Pannett, AAJ, Salandre, J, Kas, K, VandeVen, WJM   +36 more
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