Results 31 to 40 of about 245,577 (122)
Spatially explicit non-Mendelian diploid model
, 2009 We introduce a spatially explicit model for the competition between type $a$ and type $b$ alleles. Each vertex of the $d$-dimensional integer lattice is occupied by a diploid individual, which is in one of three possible states or genotypes: $aa$, $ab ...
Lanchier, N., Neuhauser, C.
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Digital Health, 2023 Objective Inconsistent results were reported on the association of physical activity with ovarian cancer. However, given the limitations of confounders and inverse causation, the validity of the association remained unclear. Therefore, we conducted a two-
Jing Wang +3 more
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Theoretical impact of insecticide-impregnated school uniforms on dengue incidence in Thai children. [PDF]
, 2013 BACKGROUND: Children carry the main burden of morbidity and mortality caused by dengue. Children spend a considerable amount of their day at school; hence strategies that reduce human-mosquito contact to protect against the day-biting habits of Aedes ...
Amaku, Marcos +4 more
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Effects of epigenetic age acceleration on kidney function: a Mendelian randomization study
Clinical Epigenetics, 2023 Background Previous studies have reported cross-sectional associations between measures of epigenetic age acceleration (EAA) and kidney function phenotypes. However, the temporal and potentially causal relationships between these variables remain unclear.
Yang Pan +7 more
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A cyclical switch of gametogenic pathways in hybrids depends on the ploidy level
Communications BiologyThe cellular and molecular mechanisms governing sexual reproduction are conserved across eukaryotes. Nevertheless, hybridization can disrupt these mechanisms, leading to asexual reproduction, often accompanied by polyploidy. In this study, we investigate
Dmitrij Dedukh +6 more
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Nature Communications, 2021 Mendelian Randomization approaches are being increasingly refined, but certain statistical limitations hinder their application to GWAS. Here, the authors propose a new Mendelian Randomization method to estimate bi- directional causal effects and ...
Liza Darrous +2 more
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Wellcome Open Research, 2023 The MendelianRandomization package is a software package written for the R software environment that implements methods for Mendelian randomization based on summarized data.
Stephen Burgess +7 more
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An alternative to Kitcher's theory of conceptual progress and his account of the change of the gene concept [PDF]
, 2004 The present paper discusses Kitcher’s framework for studying conceptual change and progress. Kitcher’s core notion of reference potential is hard to apply to concrete cases.
Brigandt, Ingo
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Identification and analyses of exonic and copy number variants in spastic paraplegia
Scientific ReportsHereditary spastic paraplegias are a diverse group of degenerative disorders that are clinically categorized as isolated; with involvement of lower limb spasticity, or symptomatic, where spastic paraplegia is complicated by further neurological features.
Anum Shafique +8 more
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Molecular characterisation of integrated sequences of Banana streak virus in the banana plant genome [PDF]
, 2009 The genome of banana (Musa sp.) harbours multiple integrations of several species of Banana streak virus (BSV), certainly resulting from illegitimate recombination between host and viral DNA. Surprisingly, this pararetrovirus does not require integration
Baurens, Franc-Christophe +6 more
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