Results 101 to 110 of about 60,478 (247)

General and central obesities were associated with increased risk of inflammatory bowel disease: A large‐scale prospective cohort study

VIEW, EarlyView.
Prior evidence suggested inconsistent findings in terms of the relationship between obesity and inflammatory bowel disease (IBD) occurrence. We demonstrated that both general and central obesities were associated with an increased risk of developing IBD, ulcerative colitis, and Crohn's disease in a large‐scale prospective cohort.
Qian Zhang, Yijun Chen, Shuang Yu, Si Liu, Shutian Zhang, Shanshan Wu   +5 more
wiley   +1 more source

Schizophrenia and Types of Stroke: A Mendelian Randomization Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Previous studies suggest an association between schizophrenia and stroke, but no studies have investigated stroke subtypes. We examined potential causal associations between schizophrenia and a range of atherosclerotic, embolic, and ...
Shinya Nakada, Frederick K. Ho, Carlos Celis‐Morales, Jill P. Pell   +3 more
doaj   +1 more source

Additional file 2 of Causal effects of serum lipid biomarkers on early age-related macular degeneration using Mendelian randomization

, 2023
Fenfen Li, Yuqin Wang, Lishuang Chen, Chong Chen, Qi Chen, Lue Xiang, Feng-Qin Rao, Lijun Shen, Qinxiang Zheng, Quanyong Yi, Xiu‐Feng Huang   +10 more
openalex   +1 more source

Mass spectrometry‐based mitochondrial proteomics for cancer biomarker discovery

VIEW, EarlyView.
Figure.1 Schematic diagram of MS‐based mitochondrial proteomics for cancer biomarker discovery. The workflow highlights the integration of advanced technological platforms in mitochondrial proteomics and their application in cancer biomarker discovery.
Zheng Cao, ZiKun Song, Weijie Zhou, Xiaohui Liu, Yanling Liu, Peng R. Chen, Kun Qian   +6 more
wiley   +1 more source

Mendelian randomization analysis of druggable gene expression in liver cancer risk and autoimmune hepatitis

Discover Oncology
Background Liver cancer remains one of the most prevalent and lethal malignancies worldwide, while autoimmune hepatitis is an immune-mediated inflammatory liver disease characterized by circulating autoantibodies and distinctive histopathological ...
Mingming Lian, Jun Yao
doaj   +1 more source

Additional file 3 of Assessment of bidirectional relationships between 98 genera of the human gut microbiota and amyotrophic lateral sclerosis: a 2-sample Mendelian randomization study

, 2022
Linjing Zhang, Zhenhuang Zhuang, Gan Zhang, Tao Huang, Dongsheng Fan   +4 more
openalex   +1 more source

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou, Shi Luo, Yu Xiao, Bin Liu, Xu‐Ping Xiao   +4 more
wiley   +1 more source

Circulating adipokines and major depressive disorder: a two-sample Mendelian randomization study [PDF]

Shuyi Qiu, Binjing Dou, Guo J, Jiahong Li, Chunmei Li, Ziyu Yuan, Xianglin Hu, Junxi Pan, Yong Duan   +8 more
openalex   +1 more source

Sex Hormones and the Risk of Nasal Polyps: A Two‐Sample Mendelian Randomization Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective The pathophysiological roles of sex hormones in airway inflammation have drawn much attention recently. We aimed to explore the causal effect of sex hormones on chronic rhinosinusitis (CRS) and nasal polyps (NP) via a Mendelian randomization (MR) study.
Ying Zhu, Jia‐Yao Zhou, Shi‐Yao Zhang, Ru Tang, Chun‐Yu Luo, Yue‐Long Gu, Zhi‐Peng Li, Wei‐Tian Zhang   +7 more
wiley   +1 more source

Chinese Guidelines for the Diagnosis and Surgical Treatment of Adult Obstructive Sleep Apnea (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Obstructive sleep apnea (OSA) is a common chronic disorder characterized by abnormal breathing during sleeping. OSA can damage various organs throughout the body and is burdensome, both socially and economically. Moreover, as OSA has been increasingly studied in recent years, new evidence‐based guidelines for its diagnosis and surgical ...
Working Group of Guideline for the Diagnosis and Surgical Treatment of Adult OSA, Subspecialty Group of Laryngopharyngology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association, Subspecialty Group of Voice, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery   +7 more
wiley   +1 more source