Results 161 to 170 of about 4,310,301 (302)
Prenatal alcohol exposure and childhood atopic disease: A Mendelian randomization approach [PDF]
, 2013 Seif O. Shaheen +6 more
openalex +1 more source
Spina bifida as a multifactorial birth defect: Risk factors and genetic underpinnings
Pediatric Discovery, EarlyView.Abstract Spina bifida is a birth defect resulting from abnormal embryonic development of the neural tube. Though spina bifida is divided into several subtypes, myelomeningocele—the most severe form of spina bifida often associated with a markedly diminished quality of life—accounts for a significant portion of cases.
Ethan S. Wong +13 more
wiley +1 more source
The causal effect of red blood cell folate on genome-wide methylation in cord blood: a Mendelian randomization approach [PDF]
, 2013 Alexandra M. Binder, Karin B. Michels
openalex +1 more source
PROTEOMICS, EarlyView.ABSTRACT Chronic kidney disease (CKD) poses a significant and growing global health challenge, making early detection and slowing disease progression essential for improving patient outcomes. Traditional diagnostic methods such as glomerular filtration rate and proteinuria are insufficient to capture the complexity of CKD.
Marta B. Lopes +9 more
wiley +1 more source
Big data and machine learning to tackle diabetes management
European Journal of Clinical Investigation, Volume 53, Issue 1, January 2023., 2023 Abstract Background Type 2 Diabetes (T2D) diagnosis is based solely on glycaemia, even though it is an endpoint of numerous dysmetabolic pathways. Type 2 Diabetes complexity is challenging in a real‐world scenario; thus, dissecting T2D heterogeneity is a priority. Cluster analysis, which identifies natural clusters within multidimensional data based on
Ana F. Pina +5 more
wiley +1 more source
Determining Origins and Causes of Childhood Obesity via Mendelian Randomization Analysis
, 2008 Eric L. Ding, Frank B. Hu
openalex +2 more sources
Pest Management Science, EarlyView.A cyantraniliprole‐resistant strain of Spodoptera frugiperda with I4790K mutation exhibited a resistance ratio of 3414‐fold and high cross‐resistance to other diamide insecticides. Abstract BACKGROUND Cyantraniliprole, a diamide insecticide, is widely used in Brazil to control sucking and defoliating pests, including the fall armyworm (Spodoptera ...
Leonardo V Thiesen +7 more
wiley +1 more source
A systems medicine strategy to predict the efficacy of drugs for monogenic epilepsies
Epilepsia, Volume 63, Issue 12, Page 3125-3133, December 2022., 2022 Abstract Objective Monogenic epilepsies are rare but often severe. Because of their rarity, they are neglected by traditional drug developers. Hence, many lack effective treatments. Treatments for a disease can be discovered more quickly and economically by computationally predicting drugs that can be repurposed for it.
Basel Taweel +2 more
wiley +1 more source
International Journal of COPDNanxin Chen,1 Xuejie Si,2 Jun Wang,2 Wenjing Chen2 1First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, 250014, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, The ...
Chen N, Si X, Wang J, Chen W
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United European Gastroenterology Journal, EarlyView.ABSTRACT Background and Objective With limited evidence connecting paradoxical inflammatory bowel disease (paradoxical IBD) to the newest biologics and Janus kinase inhibitors, our study aims to investigate the occurrence of paradoxical IBD induced by these agents in treating other immune‐mediated inflammatory diseases (IMIDs).
Zhi‐Qing Zhan +3 more
wiley +1 more source