Results 161 to 170 of about 51,589 (295)

CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer [PDF]

open access: hybrid, 2015
Deborah J. Thompson   +84 more
openalex   +1 more source

Telomere Length, Epigenetic Age Acceleration, and Mortality Risk in US Adult Populations: An Additive Bayesian Network Analysis

open access: yesAging Cell, EarlyView.
Epigenetic DNA methylation‐based (DNAm) clocks, particularly GrimAge epigenetic age acceleration, outperform telomere length in predicting mortality across three US cohorts. Using Additive Bayesian Networks, we uncovered complex links among biological aging markers, sex, race, and mortality risk, highlighting the utility of DNAm‐based biomarkers in ...
May A. Beydoun   +11 more
wiley   +1 more source

Outlier Detection in Mendelian Randomization. [PDF]

open access: yesStat Med
Mandl MM   +3 more
europepmc   +1 more source

The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

open access: gold, 2013
Tove Fall   +99 more
openalex   +2 more sources

Fetuin-A and risk of coronary heart disease: A Mendelian randomization analysis and a pooled analysis of AHSG genetic variants in 7 prospective studies [PDF]

open access: green, 2015
Lars Erik Laugsand   +14 more
openalex   +1 more source

Systematic Multi‐Trait Study of Genetic Correlation and Causality Relationships Between General Medical Conditions and Mental Disorders

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Increasing evidence has highlighted bidirectional associations between mental disorders and general medical conditions, with underlying causes ranging from lifestyle habits and side effects from medications to genetic contributions. Novel methods now provide a way to estimate the shared genetic underpinnings and the possibility of
Ron Nudel   +2 more
wiley   +1 more source

Expectations for papers performing Mendelian randomization analyses. [PDF]

open access: yesPLoS Genet
Williams SM   +10 more
europepmc   +1 more source

Genetic Determinants of the Familial Hypercholesterolaemia Phenotype

open access: yesAnnals of Human Genetics, EarlyView.
ABSTRACT Individuals with familial hypercholesterolaemia (FH) have severely elevated plasma concentrations of low‐density lipoprotein cholesterol (LDL‐C) from birth and as a consequence have an elevated morbidity and mortality due to the development of coronary heart disease (CHD).
Steve Eric Humphries, Marta Futema
wiley   +1 more source

Assessing the Genetic Predisposition of Education on Myopia: A Mendelian Randomization Study [PDF]

open access: green, 2015
Gabriel Cuéllar-Partida   +12 more
openalex   +1 more source

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