Results 51 to 60 of about 4,362,965 (333)

Exploring causal correlations between inflammatory cytokines and systemic lupus erythematosus: A Mendelian randomization

Frontiers in Immunology, 2023
Objectives Previous studies have reported that a few inflammatory cytokines have associations with systemic lupus erythematosus (SLE)—for example, IL-6, IL-17, and macrophage inflammatory protein (MIP).
Mengmeng Xiang, Yilun Wang, Zhanyan Gao, Jie Wang, Qian Chen, Zhanjuan Sun, Jun Liang, Jinhua Xu   +7 more
semanticscholar   +1 more source

Vitamin D supplementation in the prevention and management of major chronic diseases not related to mineral homeostasis in adults : research for evidence and a scientific statement from the European society for clinical and economic aspects of osteoporosis and osteoarthritis (ESCEO) [PDF]

, 2017
Introduction: Optimal vitamin D status promotes skeletal health and is recommended with specific treatment in individuals at high risk for fragility fractures.
Bertoldo, Francesco, Bischoff-Ferrari, Heike A, Brandi, Maria Luisa, Bruyere, Olivier, Cianferotti, Luisella, Cooper, Cyrus, Cutolo, Maurizio, Kanis, John A, Kaufman, Jean, Reginster, Jean-Yves, Rizzoli, Rene   +10 more
core   +6 more sources

Dairy consumption and cardiometabolic diseases: systematic review and updated meta-analyses of prospective cohort studies [PDF]

, 2018
Purpose of Review Dairy products contain both beneficial and harmful nutrients in relation to cardiometabolic diseases. Here, we provide the latest scientific evidence regarding the relationship between dairy products and cardiometabolic diseases by ...
A Hruby, A Lamri, A Tremblay, A Tremblay, AG Pittas, B Haring, B Lamarche, BJ Fuhrman, D Aune, D Gao, D Hu, D Kromhout, D Mozaffarian, D Mozaffarian, Daniel Lisko, DD Alexander, DI Givens, Doreen Gille, E Yu, EM Brouwer-Brolsma, F Rosqvist, FP Hartwig, G Buckland, GC Chen, Global Burden of Disease Risk Factors Collaborators, Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration, GW Dalmeijer, HEK Virtanen, HK Bergholdt, HK Bergholdt, HK Choi, I Sluijs, J Bodner-Montville, J Goede de, J Praagman, J Praagman, JA Nettleton, Jing Guo, JJ Dinicolantonio, JM Geleijnse, JP Drouin-Chartier, JP Drouin-Chartier, JP Higgins, JR Benatar, K Ge, KM Turner, L Brink, L Gijsbers, L Pimpin, L Schwingshackl, LA Mierlo van, LET Vissers, LM O'Connor, LQ Qin, M Chen, M Ding, M Kratz, M Talaei, M Talaei, M Talaei, M Talaei, MA Aerde van, MC Oliveira Otto de, ME Labonte, Mendelian Randomization of Dairy Consumption Working Group, MU Jakobsen, N Moslehi, NM Grantham, P Elwood, PC Elwood, Q Liu, Q Yang, R Villegas, S Greenland, S Parvez, Shuang Tian, SR Bauer, SS Lim, SS Soedamah-Muthu, SS Soedamah-Muthu, U Ericson, V Dilis, X Tong   +82 more
core   +6 more sources

Targeting inflammation to reduce cardiovascular disease risk: a realistic clinical prospect? [PDF]

, 2017
Data from basic science experiments is overwhelmingly supportive of the causal role of immune-inflammatory response(s) at the core of atherosclerosis, and therefore the theoretical potential to manipulate the inflammatory response to prevent ...
Abbas, Agca, Ait-Oufella, Albert, Alexander, Alexander, Alexander, Alexander, Andersen, Aziz, Babelova, Bellosta, Bevilacqua, Bhaskar, Blom, Boekholdt, Boekholdt, Bostrom, Brånén, Bulgarelli, Bulgarelli, Burke, Cai, Cannon, Casas, Collins, Cronstein, Dahlman-Ghozlan, Danesh, Davenport, Davey Smith, Davidson, DeOliveira, Devlin, Dinarello, Duewell, Duivenvoorden, Eisenhardt, Elango, Elhage, Ettehad, Flood, Fraser, Freigang, Fulgoni, Galkina, Galkina, Garlanda, Grassia, Grassia, Greenberg, Hansson, Hauer, Herder, Holmes, Hu, Huang, Huber, Interleukin 1 Genetics Consortium, Ivandic, Kalliolias, Kaptoge, Kimura, Kinlay, Kirii, Kleinman, Koltsova, Kureishi, Kwak, Lee, Leite, Leite, Lewington, Liao, Libby, Libby, Macritchie, Maddaluno, Maeda, Maffia, Makheja, Margaritis, McInnes, Menu, Micha, Mihaylova, Mira, Mohler, Montezano, Mulhaupt, Murad, Myasoedova, Myung, Nakata, Nicholls, O'Donoghue, Ogdie, Ohta, Pauling, Peters, Qiao, Quarck, Rajamäki, Rastogi, Reiss, Rezaie-Majd, Ridker, Ridker, Rincón, Robertson, Romano, Rosenson, Rosenson, Roubille, Ryan, Rössig, Saeed, Sage, Sarwar, Sattar, Scalia, Schett, Schieffer, Schuett, Serruys, Sever, Sever, Shah, Shaposhnik, Singh, Sirtori, Sniderman, Soedamah-Muthu, Solomon, Southan, Souverein, Sprague, Srikakulapu, Strober, Sukovich, Swerdlow, Swirski, Talmud, Tay, Teng, Thompson, Tits, Toedter, Turunen, Tzellos, Walker, Wang, Wang, Watson, Weintraub, Welsh, Welsh, Welsh, Welsh, Weng, Wensley, White, Wilensky, Willeit, Willis, Wong, Woodward, Xanthoulea, Ye, Ye, Yilmaz, Youssef, Zalewski, Zhao   +173 more
core   +2 more sources

Smoking and stroke: A mendelian randomization study [PDF]

Annals of Neurology, 2019
We used the Mendelian randomization design to explore the potential causal association of smoking with ischemic stroke and intracerebral hemorrhage using summary statistics data for 34,217 ischemic stroke cases and 404,630 noncases, and 1,545 cases of intracerebral hemorrhage and 1,481 noncases.
Karl Michaëlsson, Stephen Burgess, Susanna C. Larsson, Susanna C. Larsson   +3 more
openaire   +6 more sources

Theoretical impact of insecticide-impregnated school uniforms on dengue incidence in Thai children. [PDF]

, 2013
BACKGROUND: Children carry the main burden of morbidity and mortality caused by dengue. Children spend a considerable amount of their day at school; hence strategies that reduce human-mosquito contact to protect against the day-biting habits of Aedes ...
Amaku, Marcos, Coutinho, Francisco Antonio Bezerra, Kittayapong, Pattamaporn, Massad, Eduardo, Wilder-Smith, Annelies   +4 more
core   +2 more sources

Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption

bioRxiv, 2017
Background Mendelian randomisation (MR) is being increasingly used as a strategy to improve causal inference in observational studies. Availability of summary data of genetic associations for a variety of phenotypes from large genome-wide association ...
F. Hartwig, G. Davey Smith, J. Bowden
semanticscholar   +1 more source

Study on the causal relationship between educational attainment and delirium: A two-sample Mendelian randomization study

Heliyon
This study aimed to investigate whether there is a causal relationship between educational attainment and delirium at the genetic level using the Mendelian randomization method, and provide new evidence for studies in this field.
Xianjie Wan, Hui Yu, Mingyi Yang, Weikun Hou, Jiale Xie, Ke Xu, Yujie Ma, Rui Ma, Fan Wang, Peng Xu   +9 more
doaj   +1 more source

Guidelines for performing Mendelian randomization investigations: update for summer 2023

Wellcome Open Research, 2019
This paper provides guidelines for performing Mendelian randomization investigations. It is aimed at practitioners seeking to undertake analyses and write up their findings, and at journal editors and reviewers seeking to assess Mendelian randomization ...
S. Burgess, G. D. Smith, N. Davies, F. Dudbridge, D. Gill, M. M. Glymour, F. Hartwig, Z. Kutalik, M. Holmes, C. Minelli, Jean V Morrison, W. Pan, C. Relton, E. Theodoratou, S. Swanson   +14 more
semanticscholar   +1 more source

Genetically predicted 486 blood metabolites in relation to risk of colorectal cancer: A Mendelian randomization study

Cancer Medicine, 2023
Metabolic disorders are a hallmark feature of cancer. However, the evidence for the causality of circulating metabolites to promote or prevent colorectal cancer (CRC) is still lacking.
Zhangjun Yun, Ziwei Guo, Xiao Li, Yang Shen, Mengdie Nan, Qing Dong, Li-qiong Hou   +6 more
semanticscholar   +1 more source