Results 101 to 110 of about 23,652,556 (316)
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Epilepsia Open, EarlyView.Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
Epigenetics & ChromatinBackground The DNA methylation-based epigenetic clocks are increasingly recognized for their precision in predicting aging and its health implications. Although prior research has identified connections between accelerated epigenetic aging and multiple ...
Hongwei Liu +3 more
doaj +1 more source
Frontiers in EndocrinologyBackgroundMendelian randomization is believed to attenuate the biases inherent in observational studies, yet a meta-analysis of Mendelian randomization studies in osteoporosis has not been conducted thus far.
Wenhao Ji +11 more
doaj +1 more source
Mendelian randomization analysis of MASLD-related diseases and VD.
Mendelian randomization analysis of MASLD-related diseases and VD.
Jing-Na Lin (2634634) +7 more
core +1 more source
Concept of Mendelian randomization.
, 2015 Concept of Mendelian randomization.
Albert Hofman (107303) +8 more
core +1 more source
Mendelian randomization analysis of female reproductive factors on osteoarthritis
MedicineEpidemiology shows women have a higher incidence of osteoarthritis (OA) than men. However, there is not enough evidence to suggest a direct correlation between female reproductive factors and OA. Therefore, this study will employ Mendelian randomization (MR) analysis to investigate whether there is a causal relationship between the 2. This study used a
Pang, Liang +4 more
openaire +2 more sources
Advanced Genetics, Volume 6, Issue 1, March 2025.This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley +1 more source
Dysglycemia in Depression: A Meta-Analysis of Variation and Mendelian Randomization Study
, 2022 Dysglycemia in Depression: A Meta-Analysis of Variation and Mendelian Randomization ...
Zhongming Zhao (40519) +5 more
core +1 more source
Mendelian randomization analysis of MASLD-related diseases and AD.
Mendelian randomization analysis of MASLD-related diseases and AD.
Jing-Na Lin (2634634) +7 more
core +1 more source