Results 81 to 90 of about 22,084,160 (163)

Bidirectional Two-Sample Mendelian Randomization Analysis Reveals Causal Associations Between Modifiable Risk Factors and Fibromyalgia [PDF]

Wei Zu,1,* Shaojiong Zhou,2,* Tao Du,1 Chenyanwen Zhu,3 Siyue Nie,4 Hongwei Zhu1 1Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Neurology & Innovation ...
Nie S, Du T, Zhou S, Zu W, Zhu H, Zhu C
core  

Sensitivity analysis for the univariable Mendelian randomization.

Sensitivity analysis for the univariable Mendelian randomization.
Qiu Zhang (239441), Yang Li (7082)
core   +1 more source

Neuroticism and posttraumatic stress disorder: A Mendelian randomization analysis

Brain and Behavior
AbstractObjectiveEpidemiological studies revealed an unestablished association between neuroticism and posttraumatic stress disorder (PTSD) and we conducted mendelian randomization (MR) analyses to examine whether neuroticism clusters of worry, depressed affect, and sensitivity to environmental stress and adversity (SESA) were involved in the ...
Zifan You, Shanshan Chen, Jinsong Tang
openaire   +3 more sources

Genetically predicted ankylosing spondylitis increases the risk of heart failure: a Mendelian randomization study

Frontiers in Cardiovascular Medicine
BackgroundObservational studies have indicated a potential association between ankylosing spondylitis and elevated cardiovascular disease (CVD) risk. However, it remains uncertain whether this association reflects a causal association.
Chennan Liu, Chennan Liu, Laicheng Wang, Mei Lin, Mei Lin, Jing You, Jing You, Xuan Zheng, Xuan Zheng, Ailing Wang, Ailing Wang, Yunchai Lin, Yunchai Lin, Feng Peng, Feng Peng, Dan Hu   +15 more
doaj   +1 more source

Proteome-Wide Mendelian Randomization Analysis to Identify Potential Plasma Biomarkers and Therapeutic Targets for Epithelial Ovarian Cancer Subtypes [PDF]

Qianhan Lin,1 Jiajia Li,1 Yating Sun,1 Zulimire Abudousalamu,1 Mengyang Xue,1 Liangqing Yao,2 Mo Chen1 1Department of Gynecologic Oncology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, 200011, People’s Republic of China; 2Department of
Yao L, Lin Q, Li J, Chen M, Xue M, Abudousalamu Z, Sun Y   +6 more
core  

Sensitivity analysis for the multivariable Mendelian randomization.

Sensitivity analysis for the multivariable Mendelian randomization.
Qiu Zhang (239441), Yang Li (7082)
core   +1 more source

Causal and mediating effects of lipid and facial aging: association study integrating GWAS, eQTL, mQTL, and pQTL data

Lipids in Health and Disease
Background Increasing evidence suggests a potential causal association between lipid levels and facial aging. The aim of this study was to investigate the relationship between levels of specific lipids and facial aging via Mendelian randomization methods.
Mingjian Zhao, Zhanchen He, Lukuan Liu, Yichen Wang, LinQi Gao, Yuxuan Shang, Mengru Zhu   +6 more
doaj   +1 more source

Proteome‐Wide Mendelian Randomization Identifies Therapeutic Targets for Abdominal Aortic Aneurysm

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The proteome is a key source of therapeutic targets. We conducted a comprehensive Mendelian randomization analysis across the proteome to identify potential protein markers and therapeutic targets for abdominal aortic aneurysm (AAA).
Ka Zhang, Yuan Liu, Aiqin Mao, Changzhu Li, Li Geng, Hao Kan   +5 more
doaj   +1 more source

Arachidonic acid and colorectal adenoma risk: a Mendelian randomization study

, 2018
Chelsea A Isom,1 Martha J Shrubsole,2,3 Qiuyin Cai,2 Walter E Smalley,4,5 Reid M Ness,5 Wei Zheng,2,3 Harvey J Murff3,6 1Department of General Surgery, Vanderbilt University Medical Center, Nashville, TN, USA; 2Division of Epidemiology, Vanderbilt ...
Murff HJ, Cai Q, Isom CA, Shrubsole MJ, Smalley WE, Ness RM, Zheng W   +6 more
core  

Gut microbiota, blood metabolites, & pan-cancer: a bidirectional Mendelian randomization & mediation analysis

AMB Express
We propose using Mendelian randomization analysis on GWAS data and MetaboAnalyst to model gut microbiota, metabolic pathways, blood metabolites, and cancer risk. We examined 473 gut microbiota, 205 pathways, 1400 metabolites, and 8 cancers.
Biqing Luan, Yang Yang, Qizhi Yang, Zhiqiang Li, Zhihui Xu, Yaqin Chen, Meiting Wang, Wenlin Chen, Fei Ge   +8 more
doaj   +1 more source