Results 61 to 70 of about 22,084,160 (163)

Adding Mendelian randomization to a meta-analysis—a burgeoning opportunity

Tumor Biology, 2015
Current literature is teeming with tens of thousands of meta-analyses, but only a small fraction made seminal contributions to enriching our understanding of the mechanisms of carcinogenesis, possibly due to chance, bias, confounding, or reverse causality.
Wenquan, Niu, Mingliang, Gu
openaire   +2 more sources

Associations of 35 Serum and Urine Biomarkers With Vascular Dementia—A Mendelian Randomization Study

Brain and Behavior
Background The relationship between serum and urine biomarkers with vascular dementia (VD) has been increasingly highlighted by observational studies. Yet, the causal nature underlying these associations remains elusive.
Xiaomin Zhu, Yanan Hu, Jieshuang Lin, Guifeng Zhuo, Yingrui Huang, Yulan Fu, Ying Zhang, Lin Wu, Wei Chen   +8 more
doaj   +1 more source

Genetic Markers as Instrumental Variables [PDF]

The use of genetic markers as instrumental variables (IV) is receiving increasing attention from epidemiologists, economists, statisticians and social scientists.
Frank Windmeijer, Carol Propper, Stephanie von Hinke Kessler Scholder, George Davey Smith, Debbie A. Lawlor   +4 more
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Results of Mendelian randomization analysis of PAS on intelligence.

, 2023
Results of Mendelian randomization analysis of PAS on intelligence.
Tianmin Zhu (2206318), Furong Zhang (5690462), Yushan Shi (16440272), Zhangmeng Xu (16726372), Guorong Qiu (16726375), Duoduo Yu (16726378), Guogang Dai (9228115)   +6 more
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Mendelian randomization: Principles and methods [PDF]

Mendelian randomization (MR) is a methodology for evaluating causality in observational studies. MR tries to find the fact that genotypes are not susceptible to reverse causation and confounding based on Mendel's law of inheritance.
WenJun Zhang
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Association between Lp(a) and T2D: a Mendelian randomization study

Introduction Blood lipoprotein(a) (Lp(a)) levels have been observed to be inversely correlated with type 2 diabetes (T2D). In this Mendelian randomization (MR) study, the causal impact of genetically predicted Lp(a) on T2D was assessed.
Tadeusz Osadnik, Mateusz Lejawa, Jacek Jóźwiak, Marek Gierlotka, Marcin Goławski, Maciej Banach   +5 more
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Cardiovascular diseases and depression: A meta-analysis and Mendelian randomization analysis

Molecular Psychiatry
Depression is a common psychiatric symptom among patients with cardiovascular disease (CVD), adversely affecting their health. Despite the identification of various contributing factors, the precise mechanisms linking CVD and depression remain elusive.
Jun Zeng, Yuting Qiu, Chengying Yang, Xinrong Fan, Xiangyu Zhou, Chunxiang Zhang, Sui Zhu, Yang Long, Kenji Hashimoto, Lijia Chang, Yan Wei   +10 more
openaire   +2 more sources

Mendelian Randomization Dictionary

, 2019
pdf of Lawlor DA, Wade K, et al. A Mendelian Randomization dictionary: Useful definitions and descriptions for undertaking, understanding and interpreting Mendelian Randomization ...
Professor Deborah A Lawlor
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Assessment of relationships between epigenetic age acceleration and multiple sclerosis: a bidirectional mendelian randomization study

Epigenetics & Chromatin
Background The DNA methylation-based epigenetic clocks are increasingly recognized for their precision in predicting aging and its health implications. Although prior research has identified connections between accelerated epigenetic aging and multiple ...
Hongwei Liu, Hanqing Zhang, Zhaoxu Yin, Miaomiao Hou   +3 more
doaj   +1 more source

Mendelian Randomization Analysis Supports a Causal Relationship Between Circulating Inflammatory Proteins and Basal Cell Carcinoma [PDF]

Zhi-da Fu,1,2,* Yao Wang,3,* Hong-li Yan,2 Jian-hua Wu1 1Department of Dermatology, Changhai Hospital, Naval Medical University, Shanghai, People’s Republic of China; 2Center for Reproductive Medicine, Changhai Hospital, Naval Medical University,
Yan HL, Fu ZD, Wang Y, Wu JH
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