Results 51 to 60 of about 22,084,160 (163)
Dietary factors and hypertension: A Mendelian randomization analysis
Food Science & NutritionAbstractThis research explores the causal link between dietary habits and hypertension through Mendelian randomization, providing distinct perspectives on the role of diet in addressing this worldwide health issue. Utilizing instrumental variables, we applied advanced statistical methods, including the weighted median, inverse variance weighted, and MR‐
Fanfan Li +6 more
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Modifiable factors for migraine prophylaxis: A mendelian randomization analysis
Frontiers in Pharmacology, 2023 Objective: To examine the causal effect of potentially modifiable risk factors contributing to migraine pathogenesis.Methods: We performed Mendelian randomization analyses and acquired data from United Kingdom Biobank, FinnGen Biobank, and the MRC IEU OpenGWAS data infrastructure.
Hui Zheng +4 more
openaire +3 more sources
Frontiers in NutritionBackgroundObservational studies indicate a correlation between food intake and allergic rhinitis. The potential interplay between the immune system and allergic rhinitis might contribute causally to both food intake and allergic rhinitis, providing ...
Zhi-qiang Zhang +6 more
doaj +1 more source
Diet and risk for hernia: a Mendelian randomization analysis
Frontiers in NutritionBackgroundThe relationship between dietary factors and hernias is currently unclear.MethodsThe UK Biobank was used to extract dietary factors that were used as exposures, including intake of alcohol, non-oily fish, beef, fresh fruit, oily fish, salad/raw vegetables, dried fruit, coffee, cereal, salt, tea, water, cooked vegetables, cheese, Lamb/mutton ...
Yanjiang Yang +3 more
openaire +3 more sources
Robust methods in Mendelian randomization [PDF]
, 2019 Mendelian randomization uses genetic variants as instrumental variables to estimate the causal effect of a risk factor on an outcome using observational data.
core +2 more sources
Results of Mendelian randomization analysis of intelligence on PAS.
, 2023 Results of Mendelian randomization analysis of intelligence on PAS.
Tianmin Zhu (2206318) +6 more
core +1 more source
Leukemia and risk of stroke: a Mendelian randomization analysis
BMC NeurologyObservational studies suggest an association between leukemia and stroke, but causality remains unclear. Certain leukemia types may increase stroke risk, but variations exist in stroke and mortality rates across leukemia subtypes. This study employed Mendelian randomization (MR) to investigate links between leukemia subtypes and stroke.We conducted a ...
Xiaoyao Yi +4 more
openaire +3 more sources
Mendelian randomization analyses explore the relationship between cathepsins and lung cancer
Communications Biology, 2023 Lung cancer, a major contributor to cancer-related fatalities worldwide, involves a complex pathogenesis. Cathepsins, lysosomal cysteine proteases, play roles in various physiological and pathological processes, including tumorigenesis.
Jialin Li +4 more
doaj +1 more source
BioWinfordMR: an online platform for comprehensive Mendelian randomization analysis
Frontiers in ImmunologyBackground Mendelian randomization (MR) has become a tool for the rapid and accurate identification of genetic relationships between phenotypes. However, owing to the lack of rigorous and standard analytical tools, many MR conclusions are unreproducible or controversial.
Wang, Yunfeng +4 more
openaire +2 more sources
Frontiers in Cellular and Infection MicrobiologyBackgroundRecent studies have shown that gut microbiota may be related to the occurrence of brain tumors, but direct evidence is lacking. This study used the Mendelian randomization study (MR) method to explore the potential causal link between gut ...
Jianyu Yang +7 more
doaj +1 more source