Meningeal lymphatic vessels regulate brain tumor drainage and immunity. [PDF]
Recent studies have shown that meningeal lymphatic vessels (MLVs), which are located both dorsally and basally beneath the skull, provide a route for draining macromolecules and trafficking immune cells from the central nervous system (CNS) into cervical
Hu X +21 more
europepmc +5 more sources
Evaluation of meningeal lymphatic vessels with delayed contrast enhanced vessel-wall MRI in cerebral infarction. [PDF]
Observation of the clearance of gadolinium-based contrast agents (GBCA) in patients with cerebral infarction and Moyamoya disease (MMD) using vessel-wall MRI (VW-MRI). This prospective study included 11 patients with recent cerebrovascular disorder and 6
Umehana M +19 more
europepmc +6 more sources
Overview of the meningeal lymphatic vessels in aging and central nervous system disorders. [PDF]
In the aging process and central nervous system (CNS) diseases, the functions of the meningeal lymphatic vessels (MLVs) are impaired. Alterations in MLVs have been observed in aging-related neurodegenerative diseases, brain tumors, and even ...
Jiang H +5 more
europepmc +5 more sources
Advancing insights into in vivo meningeal lymphatic vessels with stereoscopic wide-field photoacoustic microscopy. [PDF]
Meningeal lymphatic vessels (mLVs) play a pivotal role in regulating metabolic waste from cerebrospinal fluid (CSF). However, the current limitations in field of view and resolution of existing imaging techniques impede understanding the stereoscopic ...
Yang F +12 more
europepmc +5 more sources
Bidirectional roles of meningeal lymphatic vessels in brain metastases: friend and foe. [PDF]
Brain metastases constitute the most prevalent intracranial malignancies. Despite recent therapeutic advances, patient prognoses remain poor, largely due to significant treatment resistance and a highly restrictive tumor microenvironment. The rediscovery
Shao W, Zhu E, Chen D, Lu H.
europepmc +3 more sources
Brain lymphatic vessels accompanying meningeal arteries in the human
Introduction: Recent studies showed the connection between cerebrospinal fluid (CSF) and deep cervical lymph nodes (dCLN) via lymphatic vessels (LV)s. These LVs accompany dural sinuses, cranial nerves, and arteries.
Safiye Cavdar
exaly +4 more sources
The Interplay between Meningeal Lymphatic Vessels and Neuroinflammation in Neurodegenerative Diseases [PDF]
Abstract: Meningeal lymphatic vessels (MLVs) are essential for the drainage of cerebrospinal fluid, macromolecules, and immune cells in the central nervous system. They play critical roles in modulating neuroinflammation in neurodegenerative diseases. Dysfunctional MLVs have been demonstrated to increase neuroinflammation by horizontally blocking the ...
Weirong Li
exaly +4 more sources
Meningeal Lymphatic Vessels: A Drain of the Brain Involved in Neurodegeneration? [PDF]
Cheng Y, Wang YJ, Wang YJ.
europepmc +5 more sources
Inactivation of ERK1/2 signaling mediates dysfunction of basal meningeal lymphatic vessels in experimental subdural hematoma. [PDF]
Rationale: Meningeal lymphatic vessels (MLVs) are essential for the clearance of subdural hematoma (SDH). However, SDH impairs their drainage function, and the pathogenesis remains unclear.
Yuan J +17 more
europepmc +2 more sources
Distinct Role of Dural and Leptomeningeal Macrophages in Maintaining Cerebrospinal Fluid Drainage to Meningeal Lymphatic Vessels. [PDF]
Cerebrospinal fluid (CSF) drains along the perivascular space, known as the glymphatic system, to the meninges, where meningeal lymphatic vessels (MLVs) remove toxic products with excess CSF from the brain.
Lohat V +9 more
europepmc +2 more sources

