Results 21 to 30 of about 36,804 (221)

The Interplay between Meningeal Lymphatic Vessels and Neuroinflammation in Neurodegenerative Diseases. [PDF]

Curr Neuropharmacol, 2022
Meningeal lymphatic vessels (MLVs) are essential for the drainage of cerebrospinal fluid, macromolecules, and immune cells in the central nervous system.
Chen J, Pan Y, Liu Q, Li G, Chen G, Li W, Zhao W, Wang Q.   +7 more
europepmc   +6 more sources

Overview of the meningeal lymphatic vessels in aging and central nervous system disorders. [PDF]

Cell Biosci, 2022
In the aging process and central nervous system (CNS) diseases, the functions of the meningeal lymphatic vessels (MLVs) are impaired. Alterations in MLVs have been observed in aging-related neurodegenerative diseases, brain tumors, and even ...
Jiang H, Wei H, Zhou Y, Xiao X, Zhou C, Ji X.   +5 more
europepmc   +7 more sources

Enhancing Th17 cells drainage through meningeal lymphatic vessels alleviate neuroinflammation after subarachnoid hemorrhage. [PDF]

J Neuroinflammation
Subarachnoid hemorrhage (SAH) is a severe cerebrovascular disorder primarily caused by the rupture of aneurysm, which results in a high mortality rate and consequently imposes a significant burden on society.
Gao D, Zou B, Zhu K, Bi S, Zhang W, Yang X, Lai J, Liang G, Pan P.   +8 more
europepmc   +7 more sources

Evaluation of meningeal lymphatic vessels with delayed contrast enhanced vessel-wall MRI in cerebral infarction. [PDF]

Jpn J Radiol
Observation of the clearance of gadolinium-based contrast agents (GBCA) in patients with cerebral infarction and Moyamoya disease (MMD) using vessel-wall MRI (VW-MRI). This prospective study included 11 patients with recent cerebrovascular disorder and 6
Umehana M, Fushimi Y, Okuchi S, Otani S, Yamamoto T, Sakata A, Nakajima S, Ikeda S, Ito S, Grinstead J, Ahn S, Mitsumoto K, Ueno K, Wu CH, Miura S, Maki T, Chihara H, Funaki T, Arakawa Y, Nakamoto Y.   +19 more
europepmc   +5 more sources

Ultrasmall inorganic nanoparticles repair damaged meningeal lymphatic vessels to boost Parkinson's disease therapy. [PDF]

Proc Natl Acad Sci U S A
Significance Meningeal lymphatic vessels (MLVs) play a crucial role in maintaining the health of the central nervous system (CNS). Targeted repair of the damaged MLV has emerged as an innovative and promising therapeutic strategy for treating these ...
Han M, Han Y, Jiang Z, Gao Y, Cao G, Zhang H, Wang T, Li Z.   +7 more
europepmc   +4 more sources

How Do Meningeal Lymphatic Vessels Drain the CNS? [PDF]

Trends Neurosci, 2016
The many interactions between the nervous and the immune systems, which are active in both physiological and pathological states, have recently become more clearly delineated with the discovery of a meningeal lymphatic system capable of carrying fluid, immune cells, and macromolecules from the central nervous system (CNS) to the draining deep cervical ...
Raper D, Louveau A, Kipnis J.
europepmc   +7 more sources

Application of optical coherence tomography for in vivo monitoring of the meningeal lymphatic vessels during opening of blood-brain barrier: mechanisms of brain clearing. [PDF]

J Biomed Opt, 2017
. The meningeal lymphatic vessels were discovered 2 years ago as the drainage system involved in the mechanisms underlying the clearance of waste products from the brain.
Semyachkina-Glushkovskaya O, Abdurashitov A, Dubrovsky A, Bragin D, Bragina O, Shushunova N, Maslyakova G, Navolokin N, Bucharskaya A, Tuchin V, Kurths J, Shirokov A.   +11 more
europepmc   +7 more sources

Meningeal Lymphatic Vessels: A Drain of the Brain Involved in Neurodegeneration? [PDF]

Neurosci Bull, 2020
Cheng Y, Wang YJ, Wang YJ.
europepmc   +7 more sources

Piezo1 agonist restores meningeal lymphatic vessels, drainage, and brain-CSF perfusion in craniosynostosis and aged mice. [PDF]

J Clin Invest, 2023
Skull development coincides with the onset of cerebrospinal fluid (CSF) circulation, brain-CSF perfusion, and meningeal lymphangiogenesis, processes essential for brain waste clearance.
Matrongolo MJ, Ang PS, Wu J, Jain A, Thackray JK, Reddy A, Sung CC, Barbet G, Hong YK, Tischfield MA.   +9 more
europepmc   +4 more sources

Inactivation of ERK1/2 signaling mediates dysfunction of basal meningeal lymphatic vessels in experimental subdural hematoma. [PDF]

Theranostics, 2023
Rationale: Meningeal lymphatic vessels (MLVs) are essential for the clearance of subdural hematoma (SDH). However, SDH impairs their drainage function, and the pathogenesis remains unclear.
Yuan J, Liu X, Nie M, Chen Y, Liu M, Huang J, Jiang W, Gao C, Quan W, Gong Z, Xiang T, Zhang X, Sha Z, Wu C, Wang D, Li S, Zhang J, Jiang R.   +17 more
europepmc   +4 more sources