Supplementary movie 1. Meningeal lymphatic vessels in close proximity to blood vessels. Lymphatic vessels are visualized in green color and blood vessels in red color.
Reidun Torp (608577) +3 more
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Photodynamic therapy of brain tumors and novel optical coherence tomography strategies for in vivo monitoring of cerebral fluid dynamics [PDF]
Photodynamic therapy (PDT) is a promising tool for least-invasive alternative methods for the treatment of brain tumors. The newly discovered PDT-induced opening of the blood–brain barrier (BBB) permeability open novel strategies for drug-brain delivery ...
A. Abdurashitov +2 more
doaj +1 more source
Lymphatic vascular morphogenesis in development, physiology, and disease [PDF]
The lymphatic vasculature constitutes a highly specialized part of the vascular system that is essential for the maintenance of interstitial fluid balance, uptake of dietary fat, and immune response. Recently, there has been an increased awareness of the
Amélie Sabine +9 more
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Meningeal lymphatics and their role in CNS disorder treatment: moving past misconceptions
The central nervous system (CNS) was previously thought to lack lymphatics and shielded from the free diffusion of molecular and cellular components by the blood–brain barrier (BBB) and the blood–cerebrospinal fluid barrier (BCB).
Alexandra Melloni +8 more
doaj +1 more source
Advancing insights into in vivo meningeal lymphatic vessels with stereoscopic wide-field photoacoustic microscopy. [PDF]
AbstractMeningeal lymphatic vessels (mLVs) play a pivotal role in regulating metabolic waste from cerebrospinal fluid (CSF). However, the current limitations in field of view and resolution of existing imaging techniques impede understanding the stereoscopic morphology and dynamic behavior of mLVs in vivo.
Yang F +12 more
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Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures [PDF]
Insertion of bone substitution materials accelerates healing of osteoporotic fractures. Biodegradable materials are preferred for application in osteoporotic patients to avoid a second surgery for implant replacement. Degraded implant fragments are often
Vivien Kauschke +50 more
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Mapping meningeal vasculature in non-human primates
Background. The blood-brain barrier has been the focus of most prior work examining intracranial vasculature in the context of various brain diseases.1 Recently, meningeal vasculature has become more widely recognized as a key contributor to brain ...
Christopher Janson +4 more
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Optical coherent tomography and fluorescent microscopy for the study of meningeal lymphatic systems [PDF]
The development of novel technologies for the imaging of meningeal lymphatic vessels is one of the amazing trends of biophotonics thanks to discovery of brain lymphatics over several years ago.
Abdurashitov, Arkady S. +35 more
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Meningeal Lymphatics: A Review and Future Directions From a Clinical Perspective
The recent discovery of lymphatic vessels in the meningeal layers calls into question the known mechanisms of fluid and macromolecule homeostasis and immunoregulation within the central nervous system.
Korri S Hershenhouse +3 more
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Tumor-induced myeloid cell plasticity toward lymphatic endothelium [PDF]
Tumor-associated lymphangiogenesis contributes to tumor progression by regulating interstitial fluid pressure, transporting immune cells to the tumor site and providing a route for metastatic dissemination.
Baeriswyl, Vanessa
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