Results 41 to 50 of about 34,570 (162)

Photodynamic therapy of brain tumors and novel optical coherence tomography strategies for in vivo monitoring of cerebral fluid dynamics [PDF]

Journal of Innovative Optical Health Sciences, 2020
Photodynamic therapy (PDT) is a promising tool for least-invasive alternative methods for the treatment of brain tumors. The newly discovered PDT-induced opening of the blood–brain barrier (BBB) permeability open novel strategies for drug-brain delivery ...
A. Abdurashitov, V. Tuchin, O. Semyachkina-Glushkovskaya   +2 more
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The role of the meningeal lymphatic system in local meningeal inflammation and trigeminal nociception

Scientific Reports, 2022
A system of lymphatic vessels has been recently characterized in the meninges, with a postulated role in ‘cleaning’ the brain via cerebral fluid drainage.
Nikita Mikhailov, Anaïs Virenque, Kseniia Koroleva, Elisa Eme-Scolan, Matei Teleman, Ali Abdollahzadeh, Raisa Giniatullina, Oleg Gafurov, Georgii Krivoshein, Tarja Malm, Riikka H. Hämäläinen, Alejandra Sierra, Jussi Tohka, Rejane Rua, Francesco M. Noe, Rashid Giniatullin   +15 more
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Meningeal lymphatics and their role in CNS disorder treatment: moving past misconceptions

Frontiers in Neuroscience, 2023
The central nervous system (CNS) was previously thought to lack lymphatics and shielded from the free diffusion of molecular and cellular components by the blood–brain barrier (BBB) and the blood–cerebrospinal fluid barrier (BCB).
Alexandra Melloni, Alexandra Melloni, Longsha Liu, Longsha Liu, Vivek Kashinath, Reza Abdi, Khalid Shah, Khalid Shah, Khalid Shah   +8 more
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Mapping meningeal vasculature in non-human primates

Veins and Lymphatics, 2022
Background. The blood-brain barrier has been the focus of most prior work examining intracranial vasculature in the context of various brain diseases.1 Recently, meningeal vasculature has become more widely recognized as a key contributor to brain ...
Christopher Janson, Kyle Hauser, Scott Muller, Jeffrey H. Kordower, Liudmila Romanova   +4 more
doaj   +1 more source

Meningeal Lymphatics: A Review and Future Directions From a Clinical Perspective

Neuroscience Insights, 2019
The recent discovery of lymphatic vessels in the meningeal layers calls into question the known mechanisms of fluid and macromolecule homeostasis and immunoregulation within the central nervous system.
Korri S Hershenhouse, Orr Shauly, Daniel J Gould, Ketan M Patel   +3 more
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The lymphatic drainage systems in the brain: a novel target for ischemic stroke?

Neural Regeneration Research, 2023
Recent studies have proposed three lymphatic drainage systems in the brain, that is, the glymphatic system, the intramural periarterial drainage pathway, and meningeal lymphatic vessels, whose roles in various neurological diseases have been widely ...
Ying-Jie Wang, Yan-Rong Sun, Yan-Hong Pei, Hao-Wen Ma, Ya-Kun Mu, Li-Hua Qin, Jun-Hao Yan   +6 more
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rTMS treatment for abrogating intracerebral hemorrhage‐induced brain parenchymal metabolite clearance dysfunction in male mice by regulating intracranial lymphatic drainage

Brain and Behavior, 2023
Background The discovery of the glymphatic system and meningeal lymphatic vessels challenged the traditional view regarding the lack of a lymphatic system in the central nervous system.
Yuheng Liu, Xuanhui Liu, Pengju Sun, Jing Li, Meng Nie, Junjie Gong, Anqi He, Mingyu Zhao, Chen Yang, Zengguang Wang   +9 more
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Abstract 1122‐000183: Assessing Meningeal Lymphatic MRI Biomarkers in Acute Large Vessel Occlusion Stroke Treated with Thrombectomy

Stroke: Vascular and Interventional Neurology, 2021
Introduction: Until recently, there was very little known about the brain’s waste removal system. Unlike the peripheral organ systems, the CNS lacked a clearly defined lymphatic vasculature and waste clearance mechanism.
Richard Pham, Rano Chatterjee
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Meningeal lymphatic vessel crosstalk with central nervous system immune cells in aging and neurodegenerative diseases

Neural Regeneration Research
Meningeal lymphatic vessels form a relationship between the nervous system and periphery, which is relevant in both health and disease. Meningeal lymphatic vessels not only play a key role in the drainage of brain metabolites but also contribute to ...
Minghuang Gao, Xinyue Wang, Shijie Su, Weicheng Feng, Yaona Lai, Kongli Huang, Dandan Cao, Qi Wang   +7 more
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Significance of developmental meningeal lymphatic dysfunction in experimental post-traumatic injury

Brain, Behavior, & Immunity - Health, 2022
Understanding the pathological mechanisms unfolding after chronic traumatic brain injury (TBI) could reveal new therapeutic entry points. During the post-TBI sequel, the involvement of cerebrospinal fluid drainage through the meningeal lymphatic vessels ...
Anaïs Virenque, Hennariikka Koivisto, Salli Antila, Emma Zub, Erin Jane Rooney, Diana Miszczuk, Adrian Müller, Enija Stoka, Nicola Marchi, Kari Alitalo, Heikki Tanila, Francesco Mattia Noe   +11 more
doaj   +1 more source