Results 41 to 50 of about 6,220 (169)

Evaluation of meningeal lymphatic vessels with delayed contrast enhanced vessel-wall MRI in cerebral infarction. [PDF]

Jpn J Radiol
Abstract Purpose Observation of the clearance of gadolinium-based contrast agents (GBCA) in patients with cerebral infarction and Moyamoya disease (MMD) using vessel-wall MRI (VW-MRI). Methods This prospective study ...
Umehana M, Fushimi Y, Okuchi S, Otani S, Yamamoto T, Sakata A, Nakajima S, Ikeda S, Ito S, Grinstead J, Ahn S, Mitsumoto K, Ueno K, Wu CH, Miura S, Maki T, Chihara H, Funaki T, Arakawa Y, Nakamoto Y.   +19 more
europepmc   +5 more sources

How Do Meningeal Lymphatic Vessels Drain the CNS? [PDF]

Trends Neurosci, 2016
The many interactions between the nervous and the immune systems, which are active in both physiological and pathological states, have recently become more clearly delineated with the discovery of a meningeal lymphatic system capable of carrying fluid, immune cells, and macromolecules from the central nervous system (CNS) to the draining deep cervical ...
Raper D, Louveau A, Kipnis J.
europepmc   +4 more sources

Piezo1 Regulates Meningeal Lymphatic Vessel Drainage and Alleviates Excessive Csf Accumulation

Nature Neuroscience
Piezo1 regulates multiple aspects of the vascular system by converting mechanical signals generated by fluid flow into biological processes. Here, we find that Piezo1 is necessary for the proper development and function of meningeal lymphatic vessels and
Zhou, Bin, Zhao, Luping, Lu, Renhao, Choi, Dongwon, Singhal, Dhruv, Hong, Young-Kwon, Lee, Sunju, Lee, Esak, Park, Eunkyung, Yu, James, Yu, Jin Suh, Kim, Chiyoon, Scallan, Joshua P, Koh, Chester J, Choi, Joshua, Nakashima, Brandon   +15 more
core   +3 more sources

Mapping meningeal vasculature in non-human primates

Veins and Lymphatics, 2022
Background. The blood-brain barrier has been the focus of most prior work examining intracranial vasculature in the context of various brain diseases.1 Recently, meningeal vasculature has become more widely recognized as a key contributor to brain ...
Christopher Janson, Kyle Hauser, Scott Muller, Jeffrey H. Kordower, Liudmila Romanova   +4 more
doaj   +1 more source

DSCR1 upregulation enhances dural meningeal lymphatic drainage to attenuate amyloid pathology of Alzheimer's disease

, 2021
Highly developed meningeal lymphatics remove waste products from the brain. Disruption of meningeal lymphatic vessels in a mouse model of amyloid pathology (5XFAD) accelerates the accumulation of amyloid plaques in the meninges and brain, and causes ...
Park, Jiyoung, Kim, Hyerin, Min, Kyung-Tai, Choi, Chiyeol, Park, Jiwon, Chang, Karen T   +5 more
core   +1 more source

Impaired meningeal lymphatic drainage in patients with idiopathic Parkinson’s disease

, 2021
Animal studies implicate meningeal lymphatic dysfunction in the pathogenesis of neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease (PD). However, there is no direct evidence in humans to support this role1–5. In this study, we
Ding, Xue Bing, Wang, Xin Xin, Liu, Han, Qin, Chi, Wang, Jiu Qi, Wang, Wei, Xia, Dan Hao, Ma, Ming Ming, Fu, Yu, Wu, Erxi, Teng, Jun Fang, Li, Jia Yi, Cao, Qin Chen, Tang, Bei Sha, Wang, Xue Jing, Chen, Yong Kang, Xiang, Zhi, Tian, Hai Yan, Zhang, Zhong Xian   +18 more
core   +1 more source

Additional file 1 of Immunohistochemical visualization of lymphatic vessels in human dura mater: methodological perspectives

, 2023
Supplementary movie 1. Meningeal lymphatic vessels in close proximity to blood vessels. Lymphatic vessels are visualized in green color and blood vessels in red color.
Reidun Torp (608577), Shreyas Balachandra Rao (15263522), César Luis Vera Quesada (15263519), Per Kristian Eide (3211218)   +3 more
core   +1 more source

Meningeal Lymphatics: A Review and Future Directions From a Clinical Perspective

Neuroscience Insights, 2019
The recent discovery of lymphatic vessels in the meningeal layers calls into question the known mechanisms of fluid and macromolecule homeostasis and immunoregulation within the central nervous system.
Korri S Hershenhouse, Orr Shauly, Daniel J Gould, Ketan M Patel   +3 more
doaj   +1 more source

Distinct Role of Dural and Leptomeningeal Macrophages in Maintaining Cerebrospinal Fluid Drainage to Meningeal Lymphatic Vessels. [PDF]

Am J Pathol
Cerebrospinal fluid (CSF) drains along the perivascular space, known as the glymphatic system, to the meninges, where meningeal lymphatic vessels (MLVs) remove toxic products with excess CSF from the brain. Macrophages are widely present in the leptomeninges and dura mater of meninges. However, whether leptomeningeal and dural macrophages play the same
Lohat V, Ilyas R, Wei Q, Oo D, Xue J, Horsman I, Keane K, Stephens M, Weid PV, Liao S.   +9 more
europepmc   +3 more sources

Additional file 2 of Immunohistochemical visualization of lymphatic vessels in human dura mater: methodological perspectives

, 2023
Supplementary movie 2. Meningeal lymphatic vessels in distance from blood vessels. Lymphatic vessels are visualized in green color.
Reidun Torp (608577), Shreyas Balachandra Rao (15263522), César Luis Vera Quesada (15263519), Per Kristian Eide (3211218)   +3 more
core   +1 more source