Scientific Reports, 2022 A system of lymphatic vessels has been recently characterized in the meninges, with a postulated role in ‘cleaning’ the brain via cerebral fluid drainage.
Nikita Mikhailov +15 more
doaj +1 more source
Meningeal lymphatic vessels in the human head: Examples of in vivo visualization with high-resolution 3T MRI [PDF]
, 2020 Felix Scholkmann, Tanja Restin
openalex +2 more sources
Meningeal lymphatics and their role in CNS disorder treatment: moving past misconceptions
Frontiers in Neuroscience, 2023 The central nervous system (CNS) was previously thought to lack lymphatics and shielded from the free diffusion of molecular and cellular components by the blood–brain barrier (BBB) and the blood–cerebrospinal fluid barrier (BCB).
Alexandra Melloni +8 more
doaj +1 more source
Pathogenetical significance of porencephalic lesions associated with intracerebral inoculation of sheep with the bovine spongiform encephalopathy (BSE) agent [PDF]
, 2009 Decreased rates of transmission of transmissible spongiform encephalopathies (TSEs) to sheep have been attributed to some polymorphisms of the prion protein (PrP) and to a ‘species barrier’ on interspecies experiments.
Card +21 more
core +1 more source
Remarkable preservation of brain tissues in an Early Cretaceous iguanodontian dinosaur [PDF]
, 2016 It has become accepted in recent years that the fossil record can preserve labile tissues. Here we report highly detailed mineralisation of soft tissues associated with a naturally occurring brain endocast of an iguanodontian dinosaur, found in ~133 Ma ...
Antcliffe, Jonathan B. +11 more
core +8 more sources
Mapping meningeal vasculature in non-human primates
Veins and Lymphatics, 2022 Background. The blood-brain barrier has been the focus of most prior work examining intracranial vasculature in the context of various brain diseases.1 Recently, meningeal vasculature has become more widely recognized as a key contributor to brain ...
Christopher Janson +4 more
doaj +1 more source
Editorial: tertiary lymphoid organs (TLOs): powerhouses of disease immunity [PDF]
, 2017 No abstract ...
Habenicht, Andreas J.R. +3 more
core +2 more sources
Brain interference: Revisiting the role of IFNγ in the central nervous system [PDF]
, 2017 Interferon gamma (IFN-gamma) is a pro-inflammatory cytokine, first described as a secreted molecule capable of interfering with viral replication. Since then, numerous other important actions in the context of the immune response to invading pathogens ...
Cerqueira, João José +4 more
core +1 more source
Intracellular uptake of macromolecules by brain lymphatic endothelial cells during zebrafish embryonic development [PDF]
, 2017 The lymphatic system controls fluid homeostasis and the clearance of macromolecules from interstitial compartments. In mammals brain lymphatics were only recently discovered, with significant implications for physiology and disease. We examined zebrafish
Hawkins, TA +5 more
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Meningeal Lymphatics: A Review and Future Directions From a Clinical Perspective
Neuroscience Insights, 2019 The recent discovery of lymphatic vessels in the meningeal layers calls into question the known mechanisms of fluid and macromolecule homeostasis and immunoregulation within the central nervous system.
Korri S Hershenhouse +3 more
doaj +1 more source