Results 51 to 60 of about 373,387 (179)

DSCR1 upregulation enhances dural meningeal lymphatic drainage to attenuate amyloid pathology of Alzheimer's disease

open access: yes, 2021
Highly developed meningeal lymphatics remove waste products from the brain. Disruption of meningeal lymphatic vessels in a mouse model of amyloid pathology (5XFAD) accelerates the accumulation of amyloid plaques in the meninges and brain, and causes ...
Park, Jiyoung   +5 more
core   +1 more source

The lymphatic drainage systems in the brain: a novel target for ischemic stroke?

open access: yesNeural Regeneration Research, 2023
Recent studies have proposed three lymphatic drainage systems in the brain, that is, the glymphatic system, the intramural periarterial drainage pathway, and meningeal lymphatic vessels, whose roles in various neurological diseases have been widely ...
Ying-Jie Wang   +6 more
doaj   +1 more source

rTMS treatment for abrogating intracerebral hemorrhage‐induced brain parenchymal metabolite clearance dysfunction in male mice by regulating intracranial lymphatic drainage

open access: yesBrain and Behavior, 2023
Background The discovery of the glymphatic system and meningeal lymphatic vessels challenged the traditional view regarding the lack of a lymphatic system in the central nervous system.
Yuheng Liu   +9 more
doaj   +1 more source

Application of optical coherence tomography for in vivo monitoring of the meningeal lymphatic vessels during opening of blood-brain barrier: mechanisms of brain clearing. [PDF]

open access: yesJ Biomed Opt, 2017
The meningeal lymphatic vessels were discovered 2 years ago as the drainage system involved in the mechanisms underlying the clearance of waste products from the brain.
Semyachkina-Glushkovskaya O   +11 more
europepmc   +2 more sources

Abstract 1122‐000183: Assessing Meningeal Lymphatic MRI Biomarkers in Acute Large Vessel Occlusion Stroke Treated with Thrombectomy

open access: yesStroke: Vascular and Interventional Neurology, 2021
Introduction: Until recently, there was very little known about the brain’s waste removal system. Unlike the peripheral organ systems, the CNS lacked a clearly defined lymphatic vasculature and waste clearance mechanism.
Richard Pham, Rano Chatterjee
doaj   +1 more source

DataSheet1_Widespread distribution of lymphatic vessels in human dura mater remote from sinus veins.PDF

open access: yes, 2023
Background and purpose: Previous experimental studies have shown that meningeal lymphatic vessels are located primarily along the walls of the dural sinus veins.
César Luis Vera Quesada (17004684)   +3 more
core   +1 more source

Significance of developmental meningeal lymphatic dysfunction in experimental post-traumatic injury

open access: yesBrain, Behavior, & Immunity - Health, 2022
Understanding the pathological mechanisms unfolding after chronic traumatic brain injury (TBI) could reveal new therapeutic entry points. During the post-TBI sequel, the involvement of cerebrospinal fluid drainage through the meningeal lymphatic vessels ...
Anaïs Virenque   +11 more
doaj   +1 more source

The Role of Meningeal Lymphatic Vessels in the CNS clearance

open access: yes, 2022
Faculty: Faculty of Biological and Environmental Sciences Degree programme: Master’s programme in Neuroscience Study track: Neuroscience Author: Enija Stoka Title: The Role of Meningeal Lymphatic Vessels in the CNS clearance Level: Master’s thesis
Stoka, Enija
core  

Neuroinflammation-Driven Lymphangiogenesis in CNS Diseases

open access: yesFrontiers in Cellular Neuroscience, 2021
The central nervous system (CNS) undergoes immunosurveillance despite the lack of conventional antigen presenting cells and lymphatic vessels in the CNS parenchyma. Additionally, the CNS is bathed in a cerebrospinal fluid (CSF).
Martin Hsu   +3 more
doaj   +1 more source

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

open access: yesAdvanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun   +12 more
wiley   +1 more source

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