Results 31 to 40 of about 36,804 (221)

Distinct Role of Dural and Leptomeningeal Macrophages in Maintaining Cerebrospinal Fluid Drainage to Meningeal Lymphatic Vessels. [PDF]

Am J Pathol
Cerebrospinal fluid (CSF) drains along the perivascular space, known as the glymphatic system, to the meninges, where meningeal lymphatic vessels (MLVs) remove toxic products with excess CSF from the brain.
Lohat V, Ilyas R, Wei Q, Oo D, Xue J, Horsman I, Keane K, Stephens M, Weid PV, Liao S.   +9 more
europepmc   +4 more sources

The meningeal lymphatic vessels and the glymphatic system: Potential therapeutic targets in neurological disorders. [PDF]

J Cereb Blood Flow Metab, 2022
The recent discovery of the meningeal lymphatic vessels (mLVs) and glymphatic pathways has challenged the long-lasting dogma that the central nervous system (CNS) lacks a lymphatic system and therefore does not interact with peripheral immunity.
Li G, Cao Y, Tang X, Huang J, Cai L, Zhou L.   +5 more
europepmc   +4 more sources

Correction: Tian et al. The Underlying Role of the Glymphatic System and Meningeal Lymphatic Vessels in Cerebral Small Vessel Disease. Biomolecules 2022, 12, 748. [PDF]

Biomolecules, 2023
In the published publication [...].
Tian Y, Zhao M, Chen Y, Yang M, Wang Y.
europepmc   +4 more sources

Brain lymphatic vessels accompanying meningeal arteries in the human

Translational Research in Anatomy
Introduction: Recent studies showed the connection between cerebrospinal fluid (CSF) and deep cervical lymph nodes (dCLN) via lymphatic vessels (LV)s. These LVs accompany dural sinuses, cranial nerves, and arteries.
Safiye Çavdar, Damlasu Altınöz, Tevriz Dilan Demir, Acar Bayraktaroğlu, İlke Ali Gürses, Gülnihal Özcan   +5 more
doaj   +3 more sources

Serotype-specific tropism of adeno-associated viruses in dorsal meningeal lymphatic vessels via intra-cisterna magna delivery. [PDF]

Front Immunol
Background Meningeal lymphatic vessels (mLVs) in the brain acts as the regulator that eliminates harmful macromolecules in post-cerebrospinal fluid (CSF) and facilitates immune cell migration to cervical lymph nodes. However, it still poses challenges on
Ren B, Li X, Lin X, Zhao W, Yang K, Zhang Y, Zheng W.   +6 more
europepmc   +4 more sources

Dorsal skull meningeal lymphatic vessels drain blood-solutes after intracerebral hemorrhage [PDF]

bioRxiv, 2021
Drainage of intraparenchymal hematoma is crucial for the treatment of intracerebral hemorrhage (ICH). We investigated here the possible function of the meningeal lymphatic vessels (mLVs) in ICH resolution.
Anaïs Virenque, Raz Balin, Francesco M. Noè   +2 more
semanticscholar   +3 more sources

Meningeal lymphatic vessel crosstalk with central nervous system immune cells in aging and neurodegenerative diseases

Neural Regeneration Research
Meningeal lymphatic vessels form a relationship between the nervous system and periphery, which is relevant in both health and disease. Meningeal lymphatic vessels not only play a key role in the drainage of brain metabolites but also contribute to ...
Minghuang Gao, Xinyue Wang, Shijie Su, Weicheng Feng, Yaona Lai, Kongli Huang, Dandan Cao, Qi Wang   +7 more
doaj   +4 more sources

Long-term exercise enhances meningeal lymphatic vessel plasticity and drainage in a mouse model of Alzheimer's disease [PDF]

Translational Neurodegeneration
Background Meningeal lymphatic drainage is crucial for the clearance of amyloid β (Aβ), supporting the maintenance of brain homeostasis. This makes it a promising therapeutic target for Alzheimer's disease (AD).
Yan Chen, Jiachen Cai, Yuzhu She, Xiaoxin He, Hu Feng, Xuewei Li, Yiran Wei, Yi Fan, Wen-e Zhao, Mengmei Yin, Linjuan Yuan, Yuxi Jin, Fengfei Ding, Chengyu Sheng, Junying Gao, Qian Li, Ming Xiao   +16 more
doaj   +4 more sources

Piezo1 agonist restores meningeal lymphatic vessels, drainage, and brain-CSF perfusion in craniosynostosis and aged mice

The Journal of Clinical Investigation, 2023
Skull development coincides with the onset of cerebrospinal fluid (CSF) circulation, brain-CSF perfusion, and meningeal lymphangiogenesis, processes essential for brain waste clearance.
Matt J. Matrongolo, Phillip S. Ang, Junbing Wu, Aditya Jain, Joshua K. Thackray, Akash Reddy, Chi Chang Sung, Gaëtan Barbet, Young-Kwon Hong, Max A. Tischfield   +9 more
doaj   +2 more sources

Abstract 1122‐000183: Assessing Meningeal Lymphatic MRI Biomarkers in Acute Large Vessel Occlusion Stroke Treated with Thrombectomy

Stroke: Vascular and Interventional Neurology, 2021
Introduction: Until recently, there was very little known about the brain’s waste removal system. Unlike the peripheral organ systems, the CNS lacked a clearly defined lymphatic vasculature and waste clearance mechanism.
Richard Pham, Rano Chatterjee
doaj   +2 more sources