Results 31 to 40 of about 373,387 (179)

Spatiotemporal dynamic changes of meningeal microenvironment influence meningeal lymphatic function following subarachnoid hemorrhage: from inflammatory response to tissue remodeling

Journal of Neuroinflammation
Background Meningeal lymphatic vessels (mLVs) play a critical role in clearing erythrocytes from the subarachnoid space and immune cells from the brain parenchyma following subarachnoid hemorrhage (SAH). However, the drainage function of mLVs is impaired
Bingrui Zhu, Changming Liu, Ming Luo, Jiarui Chen, Sixuan Tian, Tiantong Zhan, Yibo Liu, Haocheng Zhang, Zhen Wang, Jianmin Zhang, Yuanjian Fang, Sheng Chen, Xiaoyu Wang   +12 more
doaj   +2 more sources

Ultrasmall Inorganic Nanoparticles Repair Damaged Meningeal Lymphatic Vessels to Boost Parkinson’s Disease Therapy [PDF]

Proceedings of the National Academy of Sciences of the United States of America
Yaobao Han, Zhilin Jiang, Mengxiao Han
exaly   +2 more sources

Evaluation of meningeal lymphatic vessels with delayed contrast enhanced vessel-wall MRI in cerebral infarction. [PDF]

Jpn J Radiol
Abstract Purpose Observation of the clearance of gadolinium-based contrast agents (GBCA) in patients with cerebral infarction and Moyamoya disease (MMD) using vessel-wall MRI (VW-MRI). Methods This prospective study ...
Umehana M, Fushimi Y, Okuchi S, Otani S, Yamamoto T, Sakata A, Nakajima S, Ikeda S, Ito S, Grinstead J, Ahn S, Mitsumoto K, Ueno K, Wu CH, Miura S, Maki T, Chihara H, Funaki T, Arakawa Y, Nakamoto Y.   +19 more
europepmc   +6 more sources

The meningeal lymphatic vessels and the glymphatic system: Potential therapeutic targets in neurological disorders. [PDF]

J Cereb Blood Flow Metab, 2022
The recent discovery of the meningeal lymphatic vessels (mLVs) and glymphatic pathways has challenged the long-lasting dogma that the central nervous system (CNS) lacks a lymphatic system and therefore does not interact with peripheral immunity. This discovery has reshaped our understanding of mechanisms underlying CNS drainage. Under normal conditions,
Li G, Cao Y, Tang X, Huang J, Cai L, Zhou L.   +5 more
europepmc   +3 more sources

How Do Meningeal Lymphatic Vessels Drain the CNS? [PDF]

Trends Neurosci, 2016
The many interactions between the nervous and the immune systems, which are active in both physiological and pathological states, have recently become more clearly delineated with the discovery of a meningeal lymphatic system capable of carrying fluid, immune cells, and macromolecules from the central nervous system (CNS) to the draining deep cervical ...
Raper D, Louveau A, Kipnis J.
europepmc   +4 more sources

Gene expression in meningeal lymphatic endothelial cells following traumatic brain injury in mice.

PLoS ONE, 2022
Meningeal lymphatic vessels transport both the cerebrospinal fluid and interstitial fluid to the deep cervical lymph nodes. Traumatic brain injury (TBI) is accompanied by meningeal injury.
Ryo Shimada, Yuki Tatara, Kazuhiko Kibayashi   +2 more
doaj   +1 more source

Bidirectional roles of meningeal lymphatic vessels in brain metastases: friend and foe. [PDF]

Front Oncol
Brain metastases constitute the most prevalent intracranial malignancies. Despite recent therapeutic advances, patient prognoses remain poor, largely due to significant treatment resistance and a highly restrictive tumor microenvironment. The rediscovery of meningeal lymphatic vessels (MLVs) has provided new insights into how the brain interacts with ...
Shao W, Zhu E, Chen D, Lu H.
europepmc   +2 more sources

Immunohistochemical visualization of lymphatic vessels in human dura mater: methodological perspectives

Fluids and Barriers of the CNS, 2023
Background Despite greatly renewed interest concerning meningeal lymphatic function over recent years, the lymphatic structures of human dura mater have been less characterized. The available information derives exclusively from autopsy specimens.
César Luis Vera Quesada, Shreyas Balachandra Rao, Reidun Torp, Per Kristian Eide   +3 more
doaj   +1 more source

Additional file 2 of Immunohistochemical visualization of lymphatic vessels in human dura mater: methodological perspectives

, 2023
Supplementary movie 2. Meningeal lymphatic vessels in distance from blood vessels. Lymphatic vessels are visualized in green color.
Reidun Torp (608577), Shreyas Balachandra Rao (15263522), César Luis Vera Quesada (15263519), Per Kristian Eide (3211218)   +3 more
core   +1 more source

Research Progress on Intracranial Lymphatic Circulation and Its Involvement in Disorders

Frontiers in Neurology, 2022
The lymphatic system is an important part of the circulatory system, as an auxiliary system of the vein, which has the functions of immune defense, maintaining the stability of the internal environment, and regulating the pressure of the tissue.
Fan Chen, Xuan Xie, Liang Wang
doaj   +1 more source