Functional Assessment of the Dural Lymphatic Vessels Using Dynamic Contrast MRI in Multiple Sclerosis [PDF]
BACKGROUND AND PURPOSE: The discovery of glymphatic function in the human brain has generated interest in waste clearance mechanisms in neurological disorders such as multiple sclerosis (MS).
Gabr, Refaat E+3 more
core +5 more sources
Impaired meningeal lymphatic vessel development worsens stroke outcome [PDF]
The discovery of meningeal lymphatic vessels (LVs) has sparked interest in identifying their role in diseases of the central nervous system. Similar to peripheral LVs, meningeal LVs depend on vascular endothelial growth factor receptor-3 (VEGFR3) signaling for development.
Ann M. Stowe+9 more
openaire +3 more sources
Photobiomodulation of lymphatic drainage and clearance: perspective strategy for augmentation of meningeal lymphatic functions [PDF]
There is a hypothesis that augmentation of the drainage and clearing function of the meningeal lymphatic vessels (MLVs) might be a promising therapeutic target for preventing neurological diseases.
Abdurashitov, Arkady+14 more
core +2 more sources
Waste Clearance in the Brain [PDF]
Waste clearance (WC) is an essential process for brain homeostasis, which is required for the proper and healthy functioning of all cerebrovascular and parenchymal brain cells.
Chopp, Michael+8 more
core +2 more sources
Investigation of CSF outflow in mice by in vivo, dynamic magnetic resonance imaging [PDF]
The anatomical routes for the clearance of cerebrospinal fluid (CSF) remain incompletely understood. However, recent evidence has given strong support for routes leading to lymphatic vessels. A current debate centers upon the routes through which CSF can
Krämer, Jonas Uwe
core +1 more source
Dorsal skull meningeal lymphatic vessels drain blood-solutes after intracerebral hemorrhage [PDF]
AbstractDrainage of intraparenchymal hematoma is crucial for the treatment of intracerebral hemorrhage (ICH). We investigated here the possible function of the meningeal lymphatic vessels (mLVs) in ICH resolution. Meningeal lymphatics have been reported to be involved in cerebrospinal fluid drainage, but their role in the drainage and clearance of ...
Anaïs Virenque+2 more
openaire +2 more sources
Stimulation and Inhibition of Lymphangiogenesis Via Adeno-Associated Viral Gene Delivery [PDF]
The lymphatic vessels can be selectively stimulated to grow in adult mice, rats and pigs by application of viral vectors expressing the lymphangiogenic factors VEGF-C or VEGF-D.
A Anisimov+10 more
core +1 more source
Significance of developmental meningeal lymphatic dysfunction in experimental post-traumatic injury [PDF]
Publisher Copyright: © 2022 The AuthorsPeer ...
Alitalo, Kari+11 more
core +2 more sources
Central nervous system lymphatic unit, immunity, and epilepsy : Is there a link? [PDF]
Summary The recent definition of a network of lymphatic vessels in the meninges surrounding the brain and the spinal cord has advanced our knowledge on the functional anatomy of fluid movement within the central nervous system (CNS).
Abbott+108 more
core +2 more sources
Widespread distribution of lymphatic vessels in human dura mater remote from sinus veins [PDF]
Background and purpose: Previous experimental studies have shown that meningeal lymphatic vessels are located primarily along the walls of the dural sinus veins.
César Luis Vera Quesada+5 more
core +1 more source