Results 21 to 30 of about 5,777 (152)

Impaired meningeal lymphatic vessel development worsens stroke outcome [PDF]

Journal of Cerebral Blood Flow & Metabolism, 2019
The discovery of meningeal lymphatic vessels (LVs) has sparked interest in identifying their role in diseases of the central nervous system. Similar to peripheral LVs, meningeal LVs depend on vascular endothelial growth factor receptor-3 (VEGFR3) signaling for development.
Pavel Yanev, Katherine Poinsatte, Devon Hominick, Noor Khurana, Kielen R. Zuurbier, Marcus Berndt, Erik J. Plautz, Michael T. Dellinger, Ann Stowe   +8 more
openalex   +3 more sources

Therapeutic Hypothermia Alleviates Hydrocephalus and Neurological Dysfunction Post Intraventricular Hemorrhage by Enhancing Drainage of Glymphatic-Meningeal Lymphatic-Deep Cervical Lymphatic System. [PDF]

CNS Neurosci Ther
TH is expected to be a novel therapeutic strategy for hydrocephalus and neurological dysfunction post IVH. TH alleviates hydrocephalus post IVH by enhancing drainage of the glymphatic‐meningeal lymphatic‐deep cervical lymphatic system, which is the connection between the central nervous system and peripheral lymphatic system.
Yang Y, Ouyang Q, Sun Y, Liang A, Wang J, Wang K, Yuan Y, Liu Z, Huang J, Zhang Z, Wang L, Yuan Y, Wang C, Su Z, Zhang Q, Zhang L, Xiao G.   +16 more
europepmc   +2 more sources

Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI

eLife, 2017
Here, we report the existence of meningeal lymphatic vessels in human and nonhuman primates (common marmoset monkeys) and the feasibility of noninvasively imaging and mapping them in vivo with high-resolution, clinical MRI.
Martina Absinta, Seung-Kwon Ha, Govind Nair, Pascal Sati, Nicholas J Luciano, Maryknoll Palisoc, Antoine Louveau, Kareem A Zaghloul, Stefania Pittaluga, Jonathan Kipnis, Daniel S Reich   +10 more
doaj   +3 more sources

Abstract 1122‐000183: Assessing Meningeal Lymphatic MRI Biomarkers in Acute Large Vessel Occlusion Stroke Treated with Thrombectomy

Stroke: Vascular and Interventional Neurology, 2021
Introduction: Until recently, there was very little known about the brain’s waste removal system. Unlike the peripheral organ systems, the CNS lacked a clearly defined lymphatic vasculature and waste clearance mechanism.
Richard Pham, Rano Chatterjee
doaj   +2 more sources

Morphology of the glymphatic and meningeal lymphatic structures of the bottlenose dolphin [PDF]

Scientific Reports
In humans and mice, the glymphatic system, critical for central nervous system (CNS) health, relies on cardiorespiratory coupling, but has not yet been investigated in a diving mammal that routinely experiences apnea, bradycardia, and peripheral ...
Tiffany F. Keenan, Olivia N. Jackson, Nathan P. Nelson-Maney, Sentiel A. Rommel, William A. McLellan, D. Ann Pabst, Alexander M. Costidis, Kathleen M. Caron, Dawn N. Kernagis, David S. Rotstein, Molly Braun, Michael S. Tift   +11 more
doaj   +2 more sources

Distinct Role of Dural and Leptomeningeal Macrophages in Maintaining Cerebrospinal Fluid Drainage to Meningeal Lymphatic Vessels. [PDF]

Am J Pathol
Lohat V, Ilyas R, Wei Q, Oo D, Xue J, Horsman I, Keane K, Stephens M, Weid PV, Liao S.   +9 more
europepmc   +3 more sources

Meningeal lymphatics as a therapeutic target for neurodegenerative disorders [PDF]

Translational Neurodegeneration
Advancements in visualization methods have brought the meningeal lymphatic system (MLS) into the spotlight. The meningeal lymphatic vessels (mLVs) play a vital role in draining cerebrospinal fluid and immune cells, acting as a central hub for immune ...
Yijia Feng, Shengya Wang, Huwei Xia, Xinyi Jiang, Mingming Wu, Sipei Pan, Weihong Song   +6 more
doaj   +2 more sources

Correction: Tian et al. The Underlying Role of the Glymphatic System and Meningeal Lymphatic Vessels in Cerebral Small Vessel Disease. Biomolecules 2022, 12, 748. [PDF]

Biomolecules, 2023
Tian Y, Zhao M, Chen Y, Yang M, Wang Y.
europepmc   +3 more sources

Incorporating meningeal immunity into vaccine development [PDF]

Nature Communications
Meningeal immunity, a less-studied aspect of neuroimmune interactions, has recently come under the spotlight owing to the characterization of meningeal lymphatic vessels draining of the central nervous system (CNS).
Manisha Menon, Colin N. Haile, David J. Dowling   +2 more
doaj   +2 more sources

Application of optical coherence tomography for in vivo monitoring of the meningeal lymphatic vessels during opening of blood-brain barrier: mechanisms of brain clearing. [PDF]

J Biomed Opt, 2017
Semyachkina-Glushkovskaya O, Abdurashitov A, Dubrovsky A, Bragin D, Bragina O, Shushunova N, Maslyakova G, Navolokin N, Bucharskaya A, Tuchin V, Kurths J, Shirokov A.   +11 more
europepmc   +3 more sources