Dorsal skull meningeal lymphatic vessels drain blood-solutes after intracerebral hemorrhage [PDF]
, 2021 AbstractDrainage of intraparenchymal hematoma is crucial for the treatment of intracerebral hemorrhage (ICH). We investigated here the possible function of the meningeal lymphatic vessels (mLVs) in ICH resolution. Meningeal lymphatics have been reported to be involved in cerebrospinal fluid drainage, but their role in the drainage and clearance of ...
Anaïs Virenque +2 more
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Influence of meningeal lymphatic vessels on brain mechanisms
Proceedings for Annual Meeting of The Japanese Pharmacological Society, 2019 Masashi Matsuoka +3 more
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Evaluation of meningeal lymphatic vessels with delayed contrast enhanced vessel-wall MRI in cerebral infarction [PDF]
Japanese Journal of RadiologyAbstract Purpose Observation of the clearance of gadolinium-based contrast agents (GBCA) in patients with cerebral infarction and Moyamoya disease (MMD) using vessel-wall MRI (VW-MRI). Methods This prospective study ...
Masaki Umehana +19 more
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Piezo1 regulates meningeal lymphatic vessel drainage and alleviates excessive CSF accumulation [PDF]
Nature NeuroscienceAbstract Piezo1 regulates multiple aspects of the vascular system by converting mechanical signals generated by fluid flow into biological processes. Here, we find that Piezo1 is necessary for the proper development and function of meningeal lymphatic vessels and that activating Piezo1 through transgenic overexpression or treatment ...
Dongwon Choi +15 more
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Publisher Correction: Piezo1 regulates meningeal lymphatic vessel drainage and alleviates excessive CSF accumulation [PDF]
Nature NeuroscienceDongwon Choi +15 more
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Gene expression in meningeal lymphatic endothelial cells following traumatic brain injury in mice.
PLoS ONE, 2022 Meningeal lymphatic vessels transport both the cerebrospinal fluid and interstitial fluid to the deep cervical lymph nodes. Traumatic brain injury (TBI) is accompanied by meningeal injury.
Ryo Shimada +2 more
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Cells with Many Talents: Lymphatic Endothelial Cells in the Brain Meninges
Cells, 2021 The lymphatic system serves key functions in maintaining fluid homeostasis, the uptake of dietary fats in the small intestine, and the trafficking of immune cells. Almost all vascularized peripheral tissues and organs contain lymphatic vessels. The brain
Irina Suárez, Stefan Schulte-Merker
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Fluids and Barriers of the CNS, 2023 Background Despite greatly renewed interest concerning meningeal lymphatic function over recent years, the lymphatic structures of human dura mater have been less characterized. The available information derives exclusively from autopsy specimens.
César Luis Vera Quesada +3 more
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Widespread distribution of lymphatic vessels in human dura mater remote from sinus veins
Frontiers in Cell and Developmental Biology, 2023 Background and purpose: Previous experimental studies have shown that meningeal lymphatic vessels are located primarily along the walls of the dural sinus veins.
César Luis Vera Quesada +5 more
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Sustained meningeal lymphatic vessel atrophy or expansion does not alter Alzheimer’s disease-related amyloid pathology [PDF]
Nature Cardiovascular ResearchAbstractDiscovery of meningeal lymphatic vessels (LVs) in the dura mater, also known as dural LVs (dLVs) that depend on vascular endothelial growth factor C expression, has raised interest in their possible involvement in Alzheimer’s disease (AD). Here we find that in the APdE9 and 5xFAD mouse models of AD, dural amyloid-β (Aβ) is confined to blood ...
Salli Antila +26 more
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