Tertiary lymphoid organs in central nervous system autoimmunity [PDF]
, 2016 Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation in the central nervous system (CNS), which results in permanent neuronal damage and substantial disability in patients.
Mitsdoerffer, M., Peters, A.
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Cerebrospinal fluid outflow: a review of the historical and contemporary evidence for arachnoid villi, perineural routes, and dural lymphatics. [PDF]
, 2021 Cerebrospinal fluid (CSF) is produced by the choroid plexuses within the ventricles of the brain and circulates through the subarachnoid space of the skull and spinal column to provide buoyancy to and maintain fluid homeostasis of the brain and spinal ...
Proulx, Steven T.
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Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI [PDF]
eLife, 2017 Here, we report the existence of meningeal lymphatic vessels in human and nonhuman primates (common marmoset monkeys) and the feasibility of noninvasively imaging and mapping them in vivo with high-resolution, clinical MRI. On T2-FLAIR and T1-weighted black-blood imaging, lymphatic vessels enhance with gadobutrol, a gadolinium-based contrast agent with
Martina Absinta +10 more
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Open pathways for cerebrospinal fluid outflow at the cribriform plate along the olfactory nerves. [PDF]
, 2023 BACKGROUND Routes along the olfactory nerves crossing the cribriform plate that extend to lymphatic vessels within the nasal cavity have been identified as a critical cerebrospinal fluid (CSF) outflow pathway.
Aleandri, Simone +11 more
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Phototherapy of Alzheimer’s Disease: Photostimulation of Brain Lymphatics during Sleep: A Systematic Review [PDF]
, 2023 The global number of people with Alzheimer’s disease (AD) doubles every 5 years. It has been established that unless an effective treatment for AD is found, the incidence of AD will triple by 2060. However, pharmacological therapies for AD have failed to
Blokhina, Inna +8 more
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재발한 만성 경막하 혈종에서 혈관 구조 변화의 조직 병리학적 평가 [PDF]
, 2021 학위논문(석사) -- 서울대학교대학원 : 융합과학기술대학원 분자의학 및 바이오제약학과, 2021.8. 김현.Chronic subdural hematoma (cSDH) is a collection of blood in subdural space with encapsulated hematoma by neomembrane. The incidence of cSDH is increasing, especially in the aging population.
김현
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Age-related alterations in meningeal immunity drive impaired CNS lymphatic drainage [PDF]
, 2023 The meningeal lymphatic network enables the drainage of cerebrospinal fluid (CSF) and facilitates the removal of central nervous system (CNS) waste. During aging and in Alzheimer\u27s disease, impaired meningeal lymphatic drainage promotes the buildup of
Du, Siling +10 more
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Photodynamic Opening of the Blood–Brain Barrier and the Meningeal Lymphatic System: The New Niche in Immunotherapy for Brain Tumors [PDF]
, 2022 Photodynamic therapy (PDT) is a promising add-on therapy to the current standard of care for patients with glioblastoma (GBM). The traditional explanation of the anti-cancer PDT effects involves the PDT-induced generation of a singlet oxygen in the GBM ...
Blokhina, Inna +6 more
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Corpora amylacea act as containers that remove waste products from the brain [PDF]
, 2020 Corpora amylacea (CA) in the human brain are granular bodies formed by polyglucosan aggregates that amass waste products of different origins. They are generated by astrocytes, mainly during aging and neurodegenerative conditions, and are located ...
Augé Marí, Elisabet +9 more
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Impaired Meningeal Lymphatic Vessel Development Worsens Stroke Outcome [PDF]
, 2020 The discovery of meningeal lymphatic vessels (LVs) has sparked interest in identifying their role in diseases of the central nervous system. Similar to peripheral LVs, meningeal LVs depend on vascular endothelial growth factor receptor-3 (VEGFR3 ...
Berndt, Marcus +8 more
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