Widespread distribution of lymphatic vessels in human dura mater remote from sinus veins
Frontiers in Cell and Developmental Biology, 2023 Background and purpose: Previous experimental studies have shown that meningeal lymphatic vessels are located primarily along the walls of the dural sinus veins.
César Luis Vera Quesada +5 more
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Research Progress on Intracranial Lymphatic Circulation and Its Involvement in Disorders
Frontiers in Neurology, 2022 The lymphatic system is an important part of the circulatory system, as an auxiliary system of the vein, which has the functions of immune defense, maintaining the stability of the internal environment, and regulating the pressure of the tissue.
Fan Chen, Xuan Xie, Liang Wang
doaj +1 more source
Photodynamic therapy of brain tumors and novel optical coherence tomography strategies for in vivo monitoring of cerebral fluid dynamics [PDF]
Journal of Innovative Optical Health Sciences, 2020 Photodynamic therapy (PDT) is a promising tool for least-invasive alternative methods for the treatment of brain tumors. The newly discovered PDT-induced opening of the blood–brain barrier (BBB) permeability open novel strategies for drug-brain delivery ...
A. Abdurashitov +2 more
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Characteristic Features of Deep Brain Lymphatic Vessels and Their Regulation by Chronic Stress
Research, 2023 Studies have demonstrated that a functional network of meningeal lymphatic vessels exists in the brain. However, it is unknown whether lymphatic vessels could also extend deep into the brain parenchyma and whether the vessels could be regulated by ...
Junzhuang Chang +6 more
doaj +1 more source
Tertiary lymphoid organs in central nervous system autoimmunity [PDF]
, 2016 Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation in the central nervous system (CNS), which results in permanent neuronal damage and substantial disability in patients.
Mitsdoerffer, M., Peters, A.
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Anatomic evidence shows that lymphatic drainage exists in the pituitary to loop the cerebral lymphatic circulation [PDF]
, 2020 Respiratory infections can result in intracranial infections and unknown neurological symptoms. The central nervous system lacks classical meningeal lymphatic (circulation) drainage, and the exact underlying mechanisms of how immune cells from the ...
Chen, Tao +5 more
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Meningeal lymphatics and their role in CNS disorder treatment: moving past misconceptions
Frontiers in Neuroscience, 2023 The central nervous system (CNS) was previously thought to lack lymphatics and shielded from the free diffusion of molecular and cellular components by the blood–brain barrier (BBB) and the blood–cerebrospinal fluid barrier (BCB).
Alexandra Melloni +8 more
doaj +1 more source
Development and Maintenance of the Brain’s Immune Toolkit: Microglia and Non-Parenchymal Brain Macrophages [PDF]
, 2017 Microglia and non-parenchymal macrophages located in the perivascular space, the meninges and the choroid plexus are independent immune populations that play vital roles in brain development, homeostasis, and tissue healing.
Askew, Katharine E. +3 more
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Pathogenetical significance of porencephalic lesions associated with intracerebral inoculation of sheep with the bovine spongiform encephalopathy (BSE) agent [PDF]
, 2009 Decreased rates of transmission of transmissible spongiform encephalopathies (TSEs) to sheep have been attributed to some polymorphisms of the prion protein (PrP) and to a ‘species barrier’ on interspecies experiments.
Card +21 more
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Impaired brain glymphatic flow in experimental hepatic encephalopathy [PDF]
, 2018 Background & Aims: Neuronal function is exquisitely sensitive to alterations in the extracellular environment. In patients with hepatic encephalopathy (HE), accumulation of metabolic waste products and noxious substances in the interstitial fluid of the ...
Arias, Natalia +13 more
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