Results 131 to 140 of about 4,490 (191)

Glymphatics and meningeal lymphatics unlock the brain-immune code

Immunity
The central nervous system (CNS) was once perceived as entirely shielded from the immune system, protected behind the blood-brain barrier and thought to lack lymphatic drainage. However, recent evidence has challenged many dogmas in neuroimmunology.
Min Woo Kim, Jonathan Kipnis
openaire   +2 more sources

LRP4+ Astrocytes: A Unique Subpopulation Crucial for Blood Vessel Maintenance and Function in the Somatosensory Cortex of Normal and 5xFAD Mice

Glia, Volume 74, Issue 2, February 2026.
Lrp4+ astrocytes, uniquely vessel‐associated and GFAP−, are enriched in the pia. They support laminin‐α5+ basement membrane assembly and regulate vessel diameter and blood flow. They are reduced in 5xFAD brains, and their ablation worsens both vascular and Aβ pathology.
Emily Arzola, Gefei Yu, Lei Xiong, Daehoon Lee, Anika Wu, Shriya Paruchuri, Jasmine Skinner, Minghui Wang, Bin Zhang, Lin Mei, Wen‐Cheng Xiong   +10 more
wiley   +1 more source

Neurofluids: A holistic approach to their physiology, interactive dynamics and clinical implications for neurological diseases

Veins and Lymphatics, 2019
There is increasing interest in understanding the physiology of the extracellular fluid compartments in the central nervous system and their dynamic interaction.
Nivedita Agarwal, Christian Contarino, Eleuterio F. Toro   +2 more
doaj   +1 more source

Postnatal meningeal CSF transport is primarily mediated by the arachnoid and pia maters and is not altered after intraventricular hemorrhage-posthemorrhagic hydrocephalus [PDF]

BACKGROUND: CSF has long been accepted to circulate throughout the subarachnoid space, which lies between the arachnoid and pia maters of the meninges. How the CSF interacts with the cellular components of the developing postnatal meninges including the ...
Alli, Abdul-Haq O, DeFreitas, Dakota, Halupnik, Grace L, Koleske, Joshua P, Koller, Gretchen M, Koneru, Shriya, Pan, Shelei, Ramagiri, Sruthi, Strahle, Jennifer M   +8 more
core   +2 more sources

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Cardiac lymphatic vessels, transport, and healing of the infarcted heart [PDF]

, 2017
Huang, Li-Hao, Lavine, Kory J, Randolph, Gwendalyn J   +2 more
core   +2 more sources

Clearance of erythrocytes from the subarachnoid space through cribriform plate lymphatics in female mice. [PDF]

BACKGROUND Atraumatic subarachnoid haemorrhage (SAH) is associated with high morbidity and mortality. Proposed mechanisms for red blood cell (RBC) clearance from the subarachnoid space (SAS) are erythrolysis, erythrophagocytosis or through efflux ...
Madarasz, Adrian, Proulx, Steven T, Xin, Li   +2 more
core   +1 more source

Assessment of Meningeal Lymphatics in the Parasagittal Dural Space: A Prospective Feasibility Study Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging. [PDF]

Korean J Radiol, 2023
Joo B, Park M, Ahn SJ, Suh SH.
europepmc   +1 more source

Promising Strategies to Reduce the SARS-CoV-2 Amyloid Deposition in the Brain and Prevent COVID-19-Exacerbated Dementia and Alzheimer’s Disease

Pharmaceuticals
The COVID-19 pandemic, caused by infection with the SARS-CoV-2 virus, is associated with cognitive impairment and Alzheimer’s disease (AD) progression. Once it enters the brain, the SARS-CoV-2 virus stimulates accumulation of amyloids in the brain that ...
Nikita Navolokin, Viktoria Adushkina, Daria Zlatogorskaya, Valeria Telnova, Arina Evsiukova, Elena Vodovozova, Anna Eroshova, Elina Dosadina, Sergey Diduk, Oxana Semyachkina-Glushkovskaya   +9 more
doaj   +1 more source

Thoracic combined spinal-epidural (CSE) anaesthesia [PDF]

, 2008
Lataster, L. M. A., Lee, R. A., van Zundert, A. A. J., Visser, W. A., Wieringa, P. A.   +4 more
core   +1 more source